ALDOA | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	31 studies	63% ± 22%	Explore
natural killer cell	31 studies	53% ± 17%	Explore
T cell	30 studies	56% ± 21%	Explore
B cell	29 studies	49% ± 17%	Explore
CD8-positive, alpha-beta T cell	29 studies	55% ± 23%	Explore
endothelial cell	28 studies	58% ± 21%	Explore
fibroblast	27 studies	62% ± 19%	Explore
CD4-positive, alpha-beta T cell	27 studies	56% ± 23%	Explore
conventional dendritic cell	23 studies	70% ± 23%	Explore
regulatory T cell	23 studies	62% ± 20%	Explore
classical monocyte	22 studies	69% ± 20%	Explore
monocyte	21 studies	63% ± 25%	Explore
pericyte	21 studies	67% ± 24%	Explore
dendritic cell	20 studies	59% ± 22%	Explore
non-classical monocyte	20 studies	77% ± 21%	Explore
epithelial cell	20 studies	68% ± 27%	Explore
plasma cell	18 studies	54% ± 21%	Explore
smooth muscle cell	17 studies	62% ± 25%	Explore
endothelial cell of lymphatic vessel	16 studies	59% ± 17%	Explore
gamma-delta T cell	16 studies	48% ± 22%	Explore
memory B cell	16 studies	48% ± 17%	Explore
plasmacytoid dendritic cell	16 studies	58% ± 16%	Explore
connective tissue cell	15 studies	59% ± 20%	Explore
mast cell	13 studies	43% ± 24%	Explore
mature NK T cell	13 studies	50% ± 14%	Explore
mucosal invariant T cell	13 studies	50% ± 17%	Explore
basal cell	13 studies	72% ± 19%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	52% ± 18%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	49% ± 15%	Explore
ciliated cell	12 studies	51% ± 18%	Explore
astrocyte	12 studies	41% ± 25%	Explore
naive B cell	12 studies	44% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	46% ± 19%	Explore
myofibroblast cell	11 studies	64% ± 19%	Explore
innate lymphoid cell	10 studies	49% ± 22%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	61% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	55% ± 24%	Explore
myeloid cell	10 studies	65% ± 25%	Explore
plasmablast	9 studies	58% ± 25%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	64% ± 23%	Explore
neutrophil	9 studies	57% ± 24%	Explore
capillary endothelial cell	9 studies	42% ± 18%	Explore
abnormal cell	9 studies	72% ± 24%	Explore
goblet cell	9 studies	61% ± 22%	Explore
type I pneumocyte	8 studies	45% ± 7%	Explore
type II pneumocyte	8 studies	55% ± 17%	Explore
progenitor cell	8 studies	72% ± 22%	Explore
endothelial cell of artery	8 studies	47% ± 22%	Explore
enterocyte	8 studies	58% ± 29%	Explore
glutamatergic neuron	8 studies	35% ± 18%	Explore
secretory cell	7 studies	65% ± 22%	Explore
oligodendrocyte	7 studies	30% ± 12%	Explore
mesothelial cell	7 studies	69% ± 21%	Explore
vein endothelial cell	7 studies	50% ± 19%	Explore
T follicular helper cell	7 studies	48% ± 21%	Explore
microglial cell	7 studies	52% ± 27%	Explore
endothelial cell of vascular tree	7 studies	55% ± 13%	Explore
erythrocyte	7 studies	45% ± 20%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	48% ± 19%	Explore
platelet	6 studies	54% ± 14%	Explore
club cell	6 studies	62% ± 16%	Explore
epithelial cell of proximal tubule	6 studies	64% ± 24%	Explore
neuron	6 studies	50% ± 24%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	69% ± 25%	Explore
alveolar macrophage	5 studies	68% ± 28%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	44% ± 15%	Explore
ionocyte	5 studies	70% ± 14%	Explore
respiratory goblet cell	5 studies	63% ± 16%	Explore
mononuclear phagocyte	5 studies	70% ± 20%	Explore
kidney loop of Henle epithelial cell	5 studies	78% ± 20%	Explore
renal alpha-intercalated cell	5 studies	85% ± 5%	Explore
megakaryocyte	5 studies	75% ± 18%	Explore
erythroblast	5 studies	44% ± 25%	Explore
leukocyte	5 studies	55% ± 23%	Explore
GABAergic neuron	5 studies	36% ± 17%	Explore
hematopoietic stem cell	5 studies	74% ± 15%	Explore
intermediate monocyte	5 studies	78% ± 20%	Explore
oligodendrocyte precursor cell	5 studies	38% ± 18%	Explore
CD4-positive helper T cell	4 studies	36% ± 10%	Explore
hematopoietic precursor cell	4 studies	53% ± 32%	Explore
duct epithelial cell	4 studies	81% ± 4%	Explore
exhausted T cell	4 studies	74% ± 20%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	87% ± 8%	Explore
enteroendocrine cell	4 studies	62% ± 23%	Explore
intestinal crypt stem cell	4 studies	75% ± 16%	Explore
IgG plasma cell	4 studies	28% ± 9%	Explore
transit amplifying cell	4 studies	66% ± 31%	Explore
amacrine cell	4 studies	61% ± 34%	Explore
retina horizontal cell	4 studies	60% ± 31%	Explore
retinal bipolar neuron	4 studies	61% ± 31%	Explore
retinal rod cell	4 studies	60% ± 24%	Explore
precursor B cell	4 studies	48% ± 20%	Explore
immature B cell	4 studies	55% ± 18%	Explore
neuroendocrine cell	4 studies	57% ± 16%	Explore
adventitial cell	4 studies	57% ± 18%	Explore
brush cell	4 studies	43% ± 19%	Explore
mucus secreting cell	4 studies	72% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	86% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	60% ± 29%	Explore
group 3 innate lymphoid cell	4 studies	57% ± 23%	Explore
melanocyte	4 studies	67% ± 14%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	68% ± 27%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	52% ± 18%	Explore
deuterosomal cell	3 studies	74% ± 9%	Explore
hillock cell	3 studies	67% ± 32%	Explore
precursor cell	3 studies	82% ± 12%	Explore
squamous epithelial cell	3 studies	61% ± 18%	Explore
pancreatic A cell	3 studies	64% ± 28%	Explore
type B pancreatic cell	3 studies	71% ± 19%	Explore
glomerular endothelial cell	3 studies	44% ± 16%	Explore
podocyte	3 studies	79% ± 9%	Explore
renal beta-intercalated cell	3 studies	83% ± 9%	Explore
IgA plasma cell	3 studies	34% ± 6%	Explore
retinal ganglion cell	3 studies	82% ± 25%	Explore
retinal cone cell	3 studies	90% ± 7%	Explore
common myeloid progenitor	3 studies	56% ± 30%	Explore
pro-B cell	3 studies	49% ± 11%	Explore
T-helper 17 cell	3 studies	63% ± 29%	Explore
serous secreting cell	3 studies	61% ± 3%	Explore
intraepithelial lymphocyte	3 studies	68% ± 11%	Explore
endothelial cell of sinusoid	3 studies	23% ± 7%	Explore
muscle cell	3 studies	42% ± 24%	Explore
glial cell	3 studies	49% ± 23%	Explore
granulocyte	3 studies	68% ± 17%	Explore
keratinocyte	3 studies	65% ± 25%	Explore
interneuron	3 studies	22% ± 2%	Explore
T-helper 1 cell	3 studies	60% ± 28%	Explore
double negative thymocyte	3 studies	70% ± 13%	Explore
double-positive, alpha-beta thymocyte	3 studies	71% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	55% ± 20%	Explore
lung	16 studies	56% ± 16%	Explore
brain	14 studies	35% ± 17%	Explore
intestine	11 studies	48% ± 26%	Explore
kidney	7 studies	67% ± 18%	Explore
eye	6 studies	61% ± 27%	Explore
lymph node	6 studies	60% ± 20%	Explore
liver	6 studies	46% ± 23%	Explore
pancreas	4 studies	54% ± 30%	Explore
bone marrow	4 studies	39% ± 20%	Explore
skin	4 studies	53% ± 19%	Explore
uterus	3 studies	65% ± 31%	Explore
adrenal gland	3 studies	59% ± 14%	Explore
esophagus	3 studies	70% ± 26%	Explore
prostate	3 studies	40% ± 27%	Explore
thymus	3 studies	67% ± 29%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	36642.44	180 / 180	100%	40.55	430 / 430
esophagus	100%	76091.58	1445 / 1445	98%	15.86	179 / 183
stomach	100%	38307.35	358 / 359	98%	23.79	279 / 286
intestine	100%	54978.54	966 / 966	97%	26.11	511 / 527
bladder	100%	60694.81	21 / 21	95%	18.41	479 / 504
kidney	100%	49403.34	89 / 89	95%	11.36	852 / 901
skin	100%	56544.17	1807 / 1809	92%	10.48	436 / 472
lung	99%	34305.08	573 / 578	93%	9.64	1070 / 1155
breast	100%	41662.37	459 / 459	90%	9.58	1007 / 1118
uterus	100%	35407.85	170 / 170	88%	10.48	405 / 459
brain	99%	53268.24	2604 / 2642	88%	7.33	623 / 705
adrenal gland	100%	52761.39	258 / 258	86%	8.60	197 / 230
prostate	100%	39732.50	244 / 245	78%	5.12	390 / 502
pancreas	71%	14250.22	232 / 328	88%	9.46	157 / 178
thymus	100%	37931.52	650 / 653	53%	3.10	318 / 605
adipose	100%	43859.01	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	24.33	80 / 80
muscle	100%	436640.01	803 / 803	0%	0	0 / 0
spleen	100%	33323.12	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	6.97	1 / 1
blood vessel	100%	51744.40	1333 / 1335	0%	0	0 / 0
peripheral blood	99%	84701.21	921 / 929	0%	0	0 / 0
heart	98%	115259.00	840 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	10.11	43 / 45
lymph node	0%	0	0 / 0	83%	6.03	24 / 29
liver	27%	5952.88	62 / 226	25%	1.66	102 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007339	Biological process	binding of sperm to zona pellucida
GO_0006941	Biological process	striated muscle contraction
GO_0046716	Biological process	muscle cell cellular homeostasis
GO_0006096	Biological process	glycolytic process
GO_0006754	Biological process	ATP biosynthetic process
GO_0006000	Biological process	fructose metabolic process
GO_0051289	Biological process	protein homotetramerization
GO_0030388	Biological process	fructose 1,6-bisphosphate metabolic process
GO_0007015	Biological process	actin filament organization
GO_0008360	Biological process	regulation of cell shape
GO_0005615	Cellular component	extracellular space
GO_0061827	Cellular component	sperm head
GO_0005576	Cellular component	extracellular region
GO_0016020	Cellular component	membrane
GO_0070062	Cellular component	extracellular exosome
GO_0034774	Cellular component	secretory granule lumen
GO_0015629	Cellular component	actin cytoskeleton
GO_0031674	Cellular component	I band
GO_1904724	Cellular component	tertiary granule lumen
GO_1904813	Cellular component	ficolin-1-rich granule lumen
GO_0005829	Cellular component	cytosol
GO_0031093	Cellular component	platelet alpha granule lumen
GO_0031430	Cellular component	M band
GO_0005634	Cellular component	nucleus
GO_0004332	Molecular function	fructose-bisphosphate aldolase activity
GO_0015631	Molecular function	tubulin binding
GO_0045296	Molecular function	cadherin binding
GO_0042802	Molecular function	identical protein binding
GO_0003723	Molecular function	RNA binding
GO_0070061	Molecular function	fructose binding
GO_0008092	Molecular function	cytoskeletal protein binding
GO_0005515	Molecular function	protein binding
GO_0003779	Molecular function	actin binding

IV. Literature review

[source]

Gene name	ALDOA
Protein name	Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Muscle-type aldolase) Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Lung cancer antigen NY-LU-1) (Muscle-type aldolase) Fructose-bisphosphate aldolase (EC 4.1.2.13)
Synonyms	ALDA hCG_1811258
Description	FUNCTION: Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis . In addition, may also function as scaffolding protein (By similarity). .
Accessions	ENST00000562168.5 ENST00000565355.1 ENST00000643777.4 [P04075-1] ENST00000563060.6 [P04075-1] P04075 ENST00000569545.5 [P04075-1] ENST00000564688.1 ENST00000642816.3 [P04075-2] H3BR68 ENST00000569798.5 ENST00000412304.6 [P04075-1] A0A0M4FNU3 H3BQN4 H3BU78 H3BUH7 H3BMQ8 ENST00000395240.7 H3BR04 ENST00000562679.5 ENST00000566846.5 J3KPS3 ENST00000563987.5 H3BPS8

ALDOA report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review