ZFAND6 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	34 studies	29% ± 12%	Explore
B cell	31 studies	26% ± 7%	Explore
natural killer cell	26 studies	21% ± 5%	Explore
fibroblast	26 studies	25% ± 10%	Explore
macrophage	23 studies	29% ± 13%	Explore
pericyte	20 studies	25% ± 16%	Explore
smooth muscle cell	20 studies	21% ± 5%	Explore
memory B cell	17 studies	24% ± 6%	Explore
astrocyte	17 studies	35% ± 14%	Explore
ciliated cell	16 studies	37% ± 16%	Explore
mast cell	15 studies	22% ± 9%	Explore
epithelial cell	15 studies	37% ± 23%	Explore
microglial cell	14 studies	34% ± 13%	Explore
T cell	13 studies	22% ± 6%	Explore
non-classical monocyte	13 studies	29% ± 13%	Explore
capillary endothelial cell	13 studies	19% ± 3%	Explore
conventional dendritic cell	12 studies	25% ± 11%	Explore
basal cell	12 studies	34% ± 20%	Explore
endothelial cell of lymphatic vessel	12 studies	26% ± 7%	Explore
classical monocyte	11 studies	24% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	20% ± 4%	Explore
CD8-positive, alpha-beta T cell	11 studies	20% ± 5%	Explore
connective tissue cell	11 studies	23% ± 7%	Explore
monocyte	10 studies	30% ± 9%	Explore
type II pneumocyte	10 studies	35% ± 14%	Explore
mature NK T cell	10 studies	20% ± 4%	Explore
oligodendrocyte precursor cell	10 studies	29% ± 10%	Explore
myeloid cell	10 studies	31% ± 11%	Explore
gamma-delta T cell	10 studies	22% ± 9%	Explore
type I pneumocyte	9 studies	29% ± 9%	Explore
naive B cell	9 studies	20% ± 4%	Explore
myofibroblast cell	9 studies	23% ± 7%	Explore
endothelial cell of artery	9 studies	20% ± 2%	Explore
adipocyte	9 studies	44% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	21% ± 4%	Explore
CD4-positive, alpha-beta T cell	8 studies	20% ± 5%	Explore
mesothelial cell	8 studies	35% ± 14%	Explore
vein endothelial cell	8 studies	22% ± 12%	Explore
endothelial cell of vascular tree	8 studies	24% ± 11%	Explore
dendritic cell	8 studies	38% ± 15%	Explore
regulatory T cell	8 studies	18% ± 3%	Explore
oligodendrocyte	8 studies	23% ± 7%	Explore
plasma cell	7 studies	29% ± 11%	Explore
leukocyte	7 studies	26% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	21% ± 4%	Explore
club cell	7 studies	32% ± 7%	Explore
retinal cone cell	7 studies	41% ± 21%	Explore
retinal rod cell	7 studies	35% ± 10%	Explore
plasmacytoid dendritic cell	7 studies	24% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	17% ± 2%	Explore
mononuclear phagocyte	6 studies	29% ± 13%	Explore
GABAergic neuron	6 studies	27% ± 10%	Explore
alveolar macrophage	6 studies	29% ± 14%	Explore
Mueller cell	6 studies	30% ± 10%	Explore
secretory cell	6 studies	32% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	22% ± 5%	Explore
neuron	6 studies	40% ± 17%	Explore
goblet cell	6 studies	40% ± 23%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	21% ± 4%	Explore
kidney loop of Henle epithelial cell	5 studies	19% ± 3%	Explore
epithelial cell of proximal tubule	5 studies	22% ± 5%	Explore
abnormal cell	5 studies	27% ± 11%	Explore
cardiac muscle cell	5 studies	19% ± 1%	Explore
lymphocyte	5 studies	29% ± 14%	Explore
hepatocyte	5 studies	52% ± 21%	Explore
squamous epithelial cell	4 studies	46% ± 20%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	23% ± 4%	Explore
renal alpha-intercalated cell	4 studies	25% ± 5%	Explore
glial cell	4 studies	33% ± 15%	Explore
retinal pigment epithelial cell	4 studies	36% ± 17%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	33% ± 3%	Explore
glutamatergic neuron	4 studies	35% ± 11%	Explore
platelet	4 studies	19% ± 2%	Explore
enteroendocrine cell	4 studies	28% ± 15%	Explore
respiratory goblet cell	4 studies	36% ± 10%	Explore
interneuron	4 studies	30% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	20% ± 4%	Explore
pancreatic A cell	3 studies	26% ± 4%	Explore
type B pancreatic cell	3 studies	32% ± 7%	Explore
exhausted T cell	3 studies	27% ± 11%	Explore
hematopoietic precursor cell	3 studies	40% ± 14%	Explore
plasmablast	3 studies	37% ± 17%	Explore
podocyte	3 studies	29% ± 2%	Explore
neural crest cell	3 studies	27% ± 2%	Explore
placental villous trophoblast	3 studies	34% ± 8%	Explore
retinal bipolar neuron	3 studies	27% ± 8%	Explore
mucosal invariant T cell	3 studies	19% ± 2%	Explore
rod bipolar cell	3 studies	25% ± 4%	Explore
chondrocyte	3 studies	26% ± 3%	Explore
T follicular helper cell	3 studies	18% ± 1%	Explore
germinal center B cell	3 studies	33% ± 4%	Explore
myoepithelial cell	3 studies	29% ± 11%	Explore
pancreatic ductal cell	3 studies	46% ± 15%	Explore
ependymal cell	3 studies	34% ± 13%	Explore
hematopoietic stem cell	3 studies	20% ± 6%	Explore
Schwann cell	3 studies	27% ± 12%	Explore
double negative thymocyte	3 studies	22% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	20% ± 1%	Explore
mural cell	3 studies	30% ± 12%	Explore
luminal cell of prostate epithelium	3 studies	27% ± 7%	Explore
mucus secreting cell	3 studies	25% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	13 studies	33% ± 12%	Explore
brain	12 studies	25% ± 9%	Explore
peripheral blood	8 studies	24% ± 7%	Explore
kidney	7 studies	20% ± 3%	Explore
intestine	7 studies	21% ± 10%	Explore
eye	7 studies	36% ± 14%	Explore
heart	5 studies	19% ± 2%	Explore
liver	5 studies	37% ± 18%	Explore
placenta	4 studies	23% ± 7%	Explore
breast	4 studies	18% ± 1%	Explore
adipose	4 studies	26% ± 8%	Explore
pancreas	3 studies	32% ± 6%	Explore
skin	3 studies	20% ± 3%	Explore
lymph node	3 studies	17% ± 2%	Explore
prostate	3 studies	22% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3100.09	1445 / 1445	100%	30.69	183 / 183
ovary	100%	2598.66	180 / 180	100%	35.14	430 / 430
prostate	100%	3001.79	245 / 245	100%	43.28	502 / 502
breast	100%	3651.26	459 / 459	100%	60.78	1117 / 1118
thymus	100%	4169.96	653 / 653	100%	66.52	604 / 605
lung	100%	3299.54	577 / 578	100%	45.97	1155 / 1155
bladder	100%	2839.57	21 / 21	100%	38.12	503 / 504
brain	100%	2224.05	2635 / 2642	100%	47.28	704 / 705
uterus	100%	3404.48	170 / 170	100%	44.67	457 / 459
kidney	100%	3186.10	89 / 89	99%	36.32	896 / 901
intestine	100%	3428.19	966 / 966	99%	35.82	524 / 527
stomach	100%	2445.70	359 / 359	99%	31.24	284 / 286
liver	100%	3334.96	226 / 226	99%	35.00	403 / 406
pancreas	99%	1329.37	326 / 328	99%	41.66	176 / 178
adrenal gland	100%	4434.60	258 / 258	97%	39.84	224 / 230
skin	100%	2954.01	1809 / 1809	97%	46.81	458 / 472
adipose	100%	3728.62	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	52.23	29 / 29
muscle	100%	4482.81	803 / 803	0%	0	0 / 0
spleen	100%	3852.33	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	35.44	45 / 45
ureter	0%	0	0 / 0	100%	23.36	1 / 1
blood vessel	100%	3443.81	1334 / 1335	0%	0	0 / 0
heart	98%	2412.75	847 / 861	0%	0	0 / 0
peripheral blood	95%	2440.74	880 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	90%	22.19	72 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006915	Biological process	apoptotic process
GO_0006625	Biological process	protein targeting to peroxisome
GO_0015031	Biological process	protein transport
GO_0071356	Biological process	cellular response to tumor necrosis factor
GO_0043122	Biological process	regulation of canonical NF-kappaB signal transduction
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0005575	Cellular component	cellular_component
GO_0005829	Cellular component	cytosol
GO_0003677	Molecular function	DNA binding
GO_0031593	Molecular function	polyubiquitin modification-dependent protein binding
GO_0005515	Molecular function	protein binding
GO_0008270	Molecular function	zinc ion binding
GO_0003674	Molecular function	molecular_function

IV. Literature review

[source]

Gene name	ZFAND6
Protein name	AN1-type zinc finger protein 6 (Associated with PRK1 protein) (Zinc finger A20 domain-containing protein 3) Zinc finger AN1-type containing 6 AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3)
Synonyms	HT032 AWP1 ZA20D3
Description	FUNCTION: Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity). .
Accessions	ENST00000560228.5 ENST00000558087.5 [Q6FIF0-1] H0YME2 H3BMJ5 ENST00000558997.5 Q6FIF0 H3BPX9 ENST00000561060.5 [Q6FIF0-1] ENST00000261749.11 [Q6FIF0-1] ENST00000560392.5 ENST00000561012.5 ENST00000560470.5 ENST00000558390.5 H0YLR2 H3BM82 ENST00000564367.5 ENST00000558272.5 ENST00000559775.5 [Q6FIF0-1] ENST00000560976.5 ENST00000558688.5 H0YMG0 ENST00000613266.4 [Q6FIF0-1] ENST00000559835.5 [Q6FIF0-1] H3BP46 H0YMR5 ENST00000558494.5 [Q6FIF0-1] ENST00000616533.4 [Q6FIF0-1] ENST00000618205.4 [Q6FIF0-1] H0YK54 ENST00000558724.1 H3BT16 H0YK21 ENST00000559157.5 [Q6FIF0-2]

ZFAND6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review