TOMM20 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030150Biological processprotein import into mitochondrial matrix
GO_0006626Biological processprotein targeting to mitochondrion
GO_0016031Biological processtRNA import into mitochondrion
GO_0045040Biological processprotein insertion into mitochondrial outer membrane
GO_0005741Cellular componentmitochondrial outer membrane
GO_0097225Cellular componentsperm midpiece
GO_0140596Cellular componentTOM complex
GO_0005742Cellular componentmitochondrial outer membrane translocase complex
GO_0071944Cellular componentcell periphery
GO_0044233Cellular componentmitochondria-associated endoplasmic reticulum membrane contact site
GO_0140494Cellular componentmigrasome
GO_0005739Cellular componentmitochondrion
GO_0008320Molecular functionprotein transmembrane transporter activity
GO_0030943Molecular functionmitochondrion targeting sequence binding
GO_0015450Molecular functionprotein-transporting ATPase activity
GO_0005515Molecular functionprotein binding
GO_0051082Molecular functionunfolded protein binding

IV. Literature review

[source]
Gene nameTOMM20
Protein nameMitochondrial import receptor subunit TOM20 homolog (Mitochondrial 20 kDa outer membrane protein) (Outer mitochondrial membrane receptor Tom20)
SynonymsKIAA0016
DescriptionFUNCTION: Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity). Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases. .

AccessionsQ15388
ENST00000366607.5