TMEM14B | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
CD8-positive, alpha-beta T cell	28 studies	27% ± 9%	Explore
CD4-positive, alpha-beta T cell	27 studies	30% ± 11%	Explore
B cell	25 studies	26% ± 8%	Explore
macrophage	25 studies	25% ± 9%	Explore
conventional dendritic cell	23 studies	29% ± 13%	Explore
fibroblast	23 studies	26% ± 10%	Explore
natural killer cell	21 studies	21% ± 7%	Explore
endothelial cell	21 studies	27% ± 12%	Explore
regulatory T cell	21 studies	30% ± 8%	Explore
T cell	19 studies	27% ± 7%	Explore
smooth muscle cell	19 studies	24% ± 5%	Explore
ciliated cell	17 studies	55% ± 19%	Explore
classical monocyte	17 studies	25% ± 9%	Explore
pericyte	17 studies	23% ± 5%	Explore
epithelial cell	16 studies	35% ± 21%	Explore
memory B cell	15 studies	24% ± 5%	Explore
plasmacytoid dendritic cell	15 studies	38% ± 11%	Explore
non-classical monocyte	15 studies	28% ± 13%	Explore
endothelial cell of lymphatic vessel	14 studies	25% ± 8%	Explore
naive B cell	14 studies	23% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	27% ± 7%	Explore
gamma-delta T cell	14 studies	28% ± 13%	Explore
monocyte	13 studies	25% ± 9%	Explore
mast cell	12 studies	20% ± 4%	Explore
basal cell	12 studies	33% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	31% ± 9%	Explore
connective tissue cell	12 studies	24% ± 8%	Explore
mature NK T cell	12 studies	23% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	28% ± 10%	Explore
mucosal invariant T cell	11 studies	26% ± 6%	Explore
plasma cell	10 studies	27% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	25% ± 7%	Explore
myofibroblast cell	10 studies	25% ± 5%	Explore
dendritic cell	10 studies	41% ± 26%	Explore
astrocyte	10 studies	41% ± 18%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	31% ± 10%	Explore
capillary endothelial cell	9 studies	18% ± 2%	Explore
progenitor cell	9 studies	29% ± 8%	Explore
glutamatergic neuron	8 studies	44% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	18% ± 2%	Explore
abnormal cell	8 studies	33% ± 9%	Explore
retinal rod cell	8 studies	52% ± 21%	Explore
endothelial cell of vascular tree	8 studies	23% ± 4%	Explore
myeloid cell	8 studies	29% ± 13%	Explore
type I pneumocyte	7 studies	27% ± 12%	Explore
GABAergic neuron	7 studies	39% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	28% ± 8%	Explore
epithelial cell of proximal tubule	7 studies	28% ± 7%	Explore
kidney loop of Henle epithelial cell	7 studies	31% ± 8%	Explore
endothelial cell of artery	7 studies	19% ± 4%	Explore
mesothelial cell	7 studies	34% ± 16%	Explore
retinal cone cell	7 studies	72% ± 15%	Explore
erythrocyte	7 studies	48% ± 27%	Explore
microglial cell	7 studies	25% ± 8%	Explore
T follicular helper cell	7 studies	28% ± 3%	Explore
oligodendrocyte precursor cell	7 studies	38% ± 16%	Explore
club cell	6 studies	29% ± 12%	Explore
secretory cell	6 studies	36% ± 15%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	31% ± 7%	Explore
leukocyte	6 studies	28% ± 8%	Explore
renal alpha-intercalated cell	6 studies	46% ± 13%	Explore
erythroblast	6 studies	51% ± 21%	Explore
innate lymphoid cell	6 studies	23% ± 4%	Explore
plasmablast	5 studies	42% ± 22%	Explore
ionocyte	5 studies	27% ± 9%	Explore
mononuclear phagocyte	5 studies	30% ± 15%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	31% ± 11%	Explore
goblet cell	5 studies	28% ± 13%	Explore
intestinal crypt stem cell	5 studies	27% ± 7%	Explore
vein endothelial cell	5 studies	19% ± 3%	Explore
transit amplifying cell	5 studies	24% ± 8%	Explore
retinal ganglion cell	5 studies	48% ± 20%	Explore
lymphocyte	5 studies	25% ± 11%	Explore
type II pneumocyte	5 studies	37% ± 16%	Explore
amacrine cell	5 studies	40% ± 12%	Explore
retina horizontal cell	5 studies	48% ± 16%	Explore
Mueller cell	5 studies	35% ± 10%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	35% ± 14%	Explore
oligodendrocyte	5 studies	32% ± 7%	Explore
deuterosomal cell	4 studies	53% ± 17%	Explore
respiratory goblet cell	4 studies	30% ± 18%	Explore
pancreatic A cell	4 studies	53% ± 6%	Explore
type B pancreatic cell	4 studies	46% ± 17%	Explore
exhausted T cell	4 studies	34% ± 10%	Explore
retinal bipolar neuron	4 studies	37% ± 18%	Explore
hematopoietic stem cell	4 studies	36% ± 6%	Explore
precursor B cell	4 studies	31% ± 7%	Explore
pro-B cell	4 studies	27% ± 5%	Explore
OFF-bipolar cell	4 studies	31% ± 10%	Explore
ON-bipolar cell	4 studies	32% ± 6%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	41% ± 6%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	30% ± 5%	Explore
neuron	4 studies	34% ± 19%	Explore
T-helper 17 cell	4 studies	37% ± 18%	Explore
interneuron	4 studies	64% ± 19%	Explore
hematopoietic precursor cell	3 studies	55% ± 12%	Explore
duct epithelial cell	3 studies	27% ± 8%	Explore
pancreatic D cell	3 studies	48% ± 14%	Explore
enterocyte	3 studies	18% ± 3%	Explore
neural crest cell	3 studies	30% ± 4%	Explore
placental villous trophoblast	3 studies	30% ± 10%	Explore
neuroendocrine cell	3 studies	37% ± 12%	Explore
alveolar macrophage	3 studies	24% ± 2%	Explore
intraepithelial lymphocyte	3 studies	29% ± 8%	Explore
GABAergic amacrine cell	3 studies	30% ± 9%	Explore
glycinergic amacrine cell	3 studies	29% ± 5%	Explore
rod bipolar cell	3 studies	40% ± 3%	Explore
germinal center B cell	3 studies	25% ± 2%	Explore
intermediate monocyte	3 studies	39% ± 15%	Explore
CD4-positive helper T cell	3 studies	22% ± 8%	Explore
luminal cell of prostate epithelium	3 studies	29% ± 8%	Explore
pancreatic ductal cell	3 studies	58% ± 5%	Explore
granulocyte	3 studies	23% ± 6%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	44% ± 28%	Explore
enteroendocrine cell	3 studies	34% ± 18%	Explore
group 3 innate lymphoid cell	3 studies	33% ± 13%	Explore
T-helper 1 cell	3 studies	36% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	28% ± 3%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	28% ± 8%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	26% ± 8%	Explore
double negative thymocyte	3 studies	37% ± 19%	Explore
progenitor cell of mammary luminal epithelium	3 studies	20% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	29% ± 8%	Explore
lung	13 studies	33% ± 12%	Explore
brain	11 studies	35% ± 17%	Explore
intestine	9 studies	24% ± 10%	Explore
kidney	8 studies	24% ± 4%	Explore
eye	8 studies	41% ± 20%	Explore
liver	6 studies	33% ± 25%	Explore
bone marrow	5 studies	21% ± 4%	Explore
lymph node	5 studies	27% ± 8%	Explore
pancreas	4 studies	48% ± 12%	Explore
uterus	4 studies	35% ± 16%	Explore
breast	4 studies	22% ± 4%	Explore
placenta	3 studies	23% ± 8%	Explore
adrenal gland	3 studies	23% ± 4%	Explore
thymus	3 studies	45% ± 17%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1764.06	1445 / 1445	100%	24.23	183 / 183
ovary	100%	2064.04	180 / 180	100%	51.72	430 / 430
thymus	100%	3580.99	653 / 653	100%	35.88	605 / 605
brain	100%	2032.59	2640 / 2642	100%	22.84	705 / 705
breast	100%	2489.00	459 / 459	100%	28.66	1117 / 1118
prostate	100%	2407.51	245 / 245	100%	27.77	501 / 502
uterus	100%	1951.48	170 / 170	100%	28.27	458 / 459
stomach	100%	1987.67	359 / 359	100%	25.17	285 / 286
intestine	100%	2044.49	966 / 966	100%	25.29	525 / 527
bladder	100%	1789.19	21 / 21	100%	25.71	502 / 504
liver	100%	1437.03	225 / 226	100%	24.22	406 / 406
lung	99%	1756.61	575 / 578	100%	30.49	1155 / 1155
kidney	100%	2554.00	89 / 89	99%	19.63	896 / 901
pancreas	100%	1312.62	328 / 328	99%	18.34	177 / 178
skin	100%	2192.04	1806 / 1809	100%	28.44	470 / 472
adrenal gland	100%	3947.14	258 / 258	97%	18.73	223 / 230
adipose	100%	2468.17	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	27.56	29 / 29
muscle	100%	3016.56	803 / 803	0%	0	0 / 0
spleen	100%	1679.97	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	18.77	45 / 45
ureter	0%	0	0 / 0	100%	11.78	1 / 1
blood vessel	100%	1957.10	1333 / 1335	0%	0	0 / 0
heart	99%	2576.49	851 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	98%	18.47	78 / 80
peripheral blood	83%	1299.22	771 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	TMEM14B
Protein name	Transmembrane protein 14B
Synonyms	hCG_1782975
Description	FUNCTION: Primate-specific protein involved in cortical expansion and folding in the developing neocortex. May drive neural progenitor proliferation through nuclear translocation of IQGAP1, which in turn promotes G1/S cell cycle transitions. .
Accessions	ENST00000473276.5 ENST00000481240.5 ENST00000379542.10 [Q9NUH8-1] ENST00000460341.5 C9J786 ENST00000473807.5 F2Z2F8 ENST00000478732.1 ENST00000379530.7 [Q9NUH8-2] ENST00000473166.5 ENST00000467229.1 H7C5F1 ENST00000463448.5 C9JDJ4 ENST00000467317.5 Q9NUH8 ENST00000463100.5 A0A087WU83 ENST00000475942.5 ENST00000612333.4 C9JQS0 B4DFL6 C9JCY4 ENST00000461342.5 H7C541

GO_0070453	Biological process	regulation of heme biosynthetic process
GO_0021987	Biological process	cerebral cortex development
GO_2000045	Biological process	regulation of G1/S transition of mitotic cell cycle
GO_0061351	Biological process	neural precursor cell proliferation
GO_0031966	Cellular component	mitochondrial membrane
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

TMEM14B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review