SLIRP | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	34 studies	35% ± 18%	Explore
fibroblast	32 studies	31% ± 15%	Explore
macrophage	28 studies	29% ± 13%	Explore
pericyte	25 studies	36% ± 14%	Explore
smooth muscle cell	24 studies	35% ± 11%	Explore
epithelial cell	22 studies	40% ± 21%	Explore
conventional dendritic cell	22 studies	29% ± 12%	Explore
natural killer cell	21 studies	21% ± 7%	Explore
basal cell	20 studies	37% ± 14%	Explore
non-classical monocyte	20 studies	32% ± 11%	Explore
classical monocyte	19 studies	27% ± 8%	Explore
CD8-positive, alpha-beta T cell	18 studies	25% ± 11%	Explore
regulatory T cell	18 studies	23% ± 8%	Explore
B cell	17 studies	24% ± 10%	Explore
monocyte	17 studies	30% ± 12%	Explore
endothelial cell of lymphatic vessel	16 studies	39% ± 13%	Explore
ciliated cell	16 studies	47% ± 17%	Explore
connective tissue cell	16 studies	34% ± 11%	Explore
CD4-positive, alpha-beta T cell	15 studies	27% ± 12%	Explore
T cell	15 studies	26% ± 15%	Explore
mast cell	14 studies	24% ± 4%	Explore
myofibroblast cell	13 studies	33% ± 13%	Explore
plasma cell	12 studies	33% ± 14%	Explore
capillary endothelial cell	12 studies	29% ± 7%	Explore
vein endothelial cell	12 studies	31% ± 10%	Explore
dendritic cell	11 studies	34% ± 23%	Explore
endothelial cell of vascular tree	11 studies	33% ± 8%	Explore
myeloid cell	11 studies	29% ± 13%	Explore
secretory cell	10 studies	35% ± 12%	Explore
progenitor cell	10 studies	47% ± 15%	Explore
abnormal cell	10 studies	34% ± 16%	Explore
endothelial cell of artery	10 studies	29% ± 9%	Explore
gamma-delta T cell	10 studies	26% ± 16%	Explore
plasmablast	9 studies	38% ± 20%	Explore
goblet cell	9 studies	39% ± 18%	Explore
memory B cell	9 studies	23% ± 9%	Explore
type I pneumocyte	8 studies	28% ± 15%	Explore
neuron	8 studies	42% ± 19%	Explore
mesothelial cell	8 studies	37% ± 18%	Explore
astrocyte	8 studies	33% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	21% ± 6%	Explore
club cell	7 studies	40% ± 10%	Explore
naive B cell	7 studies	21% ± 5%	Explore
epithelial cell of proximal tubule	7 studies	51% ± 14%	Explore
type II pneumocyte	7 studies	37% ± 21%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	24% ± 5%	Explore
plasmacytoid dendritic cell	7 studies	27% ± 12%	Explore
hematopoietic precursor cell	6 studies	32% ± 15%	Explore
respiratory goblet cell	6 studies	32% ± 17%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	27% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	18% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	21% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	20% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	19% ± 3%	Explore
kidney loop of Henle epithelial cell	6 studies	45% ± 9%	Explore
renal alpha-intercalated cell	6 studies	60% ± 6%	Explore
enterocyte	6 studies	45% ± 10%	Explore
transit amplifying cell	6 studies	44% ± 23%	Explore
retinal cone cell	6 studies	52% ± 30%	Explore
retinal rod cell	6 studies	39% ± 21%	Explore
oligodendrocyte	6 studies	32% ± 8%	Explore
T follicular helper cell	6 studies	21% ± 4%	Explore
alveolar macrophage	5 studies	25% ± 7%	Explore
ionocyte	5 studies	40% ± 9%	Explore
mononuclear phagocyte	5 studies	32% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	19% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	55% ± 15%	Explore
mature NK T cell	5 studies	20% ± 4%	Explore
enteroendocrine cell	5 studies	48% ± 20%	Explore
retinal ganglion cell	5 studies	52% ± 31%	Explore
erythroblast	5 studies	62% ± 15%	Explore
mucosal invariant T cell	5 studies	18% ± 1%	Explore
brush cell	5 studies	33% ± 19%	Explore
microglial cell	5 studies	31% ± 13%	Explore
erythrocyte	5 studies	50% ± 23%	Explore
oligodendrocyte precursor cell	5 studies	34% ± 11%	Explore
deuterosomal cell	4 studies	45% ± 16%	Explore
pancreatic A cell	4 studies	63% ± 13%	Explore
type B pancreatic cell	4 studies	62% ± 15%	Explore
leukocyte	4 studies	29% ± 11%	Explore
intestinal crypt stem cell	4 studies	48% ± 16%	Explore
innate lymphoid cell	4 studies	23% ± 7%	Explore
amacrine cell	4 studies	44% ± 20%	Explore
muscle cell	4 studies	36% ± 19%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	38% ± 10%	Explore
GABAergic neuron	4 studies	31% ± 8%	Explore
glutamatergic neuron	4 studies	40% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	22% ± 6%	Explore
hepatocyte	4 studies	55% ± 29%	Explore
T-helper 17 cell	4 studies	27% ± 11%	Explore
duct epithelial cell	3 studies	37% ± 4%	Explore
precursor cell	3 studies	42% ± 11%	Explore
pancreatic D cell	3 studies	62% ± 17%	Explore
glomerular endothelial cell	3 studies	28% ± 8%	Explore
neural crest cell	3 studies	44% ± 9%	Explore
retinal bipolar neuron	3 studies	51% ± 25%	Explore
extravillous trophoblast	3 studies	37% ± 15%	Explore
placental villous trophoblast	3 studies	64% ± 16%	Explore
common myeloid progenitor	3 studies	29% ± 11%	Explore
lymphocyte	3 studies	34% ± 7%	Explore
megakaryocyte	3 studies	26% ± 3%	Explore
neuroendocrine cell	3 studies	60% ± 16%	Explore
precursor B cell	3 studies	36% ± 11%	Explore
pro-B cell	3 studies	30% ± 6%	Explore
retina horizontal cell	3 studies	39% ± 19%	Explore
retinal pigment epithelial cell	3 studies	44% ± 29%	Explore
mucus secreting cell	3 studies	54% ± 17%	Explore
serous secreting cell	3 studies	54% ± 16%	Explore
Mueller cell	3 studies	39% ± 8%	Explore
acinar cell	3 studies	31% ± 6%	Explore
cardiac muscle cell	3 studies	29% ± 12%	Explore
germinal center B cell	3 studies	34% ± 2%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	24% ± 4%	Explore
exhausted T cell	3 studies	23% ± 7%	Explore
intermediate monocyte	3 studies	38% ± 8%	Explore
granulocyte monocyte progenitor cell	3 studies	38% ± 12%	Explore
hematopoietic stem cell	3 studies	31% ± 14%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	49% ± 14%	Explore
glial cell	3 studies	38% ± 22%	Explore
keratinocyte	3 studies	35% ± 7%	Explore
interneuron	3 studies	36% ± 9%	Explore
progenitor cell of mammary luminal epithelium	3 studies	21% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	35% ± 11%	Explore
peripheral blood	13 studies	24% ± 5%	Explore
intestine	11 studies	32% ± 17%	Explore
kidney	9 studies	35% ± 12%	Explore
eye	9 studies	36% ± 18%	Explore
brain	9 studies	34% ± 7%	Explore
liver	7 studies	38% ± 21%	Explore
pancreas	5 studies	51% ± 20%	Explore
bone marrow	5 studies	26% ± 9%	Explore
uterus	5 studies	37% ± 14%	Explore
lymph node	5 studies	25% ± 12%	Explore
placenta	4 studies	39% ± 20%	Explore
prostate	4 studies	27% ± 7%	Explore
breast	4 studies	27% ± 6%	Explore
adrenal gland	3 studies	33% ± 9%	Explore
esophagus	3 studies	44% ± 23%	Explore
skin	3 studies	24% ± 4%	Explore
thymus	3 studies	42% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	1435.61	258 / 258	100%	42.10	230 / 230
bladder	100%	1318.48	21 / 21	100%	48.36	504 / 504
brain	100%	1850.03	2642 / 2642	100%	35.13	705 / 705
esophagus	100%	1461.91	1445 / 1445	100%	41.37	183 / 183
intestine	100%	1485.97	966 / 966	100%	47.94	527 / 527
ovary	100%	944.18	180 / 180	100%	52.36	430 / 430
stomach	100%	1247.00	359 / 359	100%	46.23	286 / 286
uterus	100%	1078.55	170 / 170	100%	57.59	459 / 459
breast	100%	1295.41	459 / 459	100%	43.28	1117 / 1118
kidney	100%	1855.56	89 / 89	100%	28.84	900 / 901
thymus	100%	1205.72	652 / 653	100%	41.65	605 / 605
prostate	100%	1173.82	245 / 245	100%	44.88	501 / 502
skin	100%	1360.56	1806 / 1809	100%	42.58	471 / 472
liver	100%	1283.00	225 / 226	100%	37.29	406 / 406
lung	99%	974.24	574 / 578	100%	36.68	1154 / 1155
pancreas	99%	711.52	325 / 328	100%	37.58	178 / 178
adipose	100%	1272.73	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	48.13	80 / 80
lymph node	0%	0	0 / 0	100%	58.37	29 / 29
muscle	100%	2237.22	803 / 803	0%	0	0 / 0
spleen	100%	1109.35	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	44.84	45 / 45
ureter	0%	0	0 / 0	100%	58.65	1 / 1
blood vessel	100%	1406.33	1332 / 1335	0%	0	0 / 0
heart	99%	2094.26	850 / 861	0%	0	0 / 0
peripheral blood	26%	565.51	241 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007005	Biological process	mitochondrion organization
GO_0007338	Biological process	single fertilization
GO_0030317	Biological process	flagellated sperm motility
GO_0007286	Biological process	spermatid development
GO_0000961	Biological process	negative regulation of mitochondrial RNA catabolic process
GO_0001669	Cellular component	acrosomal vesicle
GO_0036126	Cellular component	sperm flagellum
GO_1990904	Cellular component	ribonucleoprotein complex
GO_0005759	Cellular component	mitochondrial matrix
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005739	Cellular component	mitochondrion
GO_0005634	Cellular component	nucleus
GO_0003723	Molecular function	RNA binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	SLIRP
Protein name	SRA stem-loop interacting RNA binding protein SRA stem-loop-interacting RNA-binding protein, mitochondrial
Synonyms	PD04872 C14orf156 DC50 DC23
Description	FUNCTION: RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation. .
Accessions	ENST00000556375.5 ENST00000613856.4 H0YJ40 H0YJI1 ENST00000556831.5 H0YJW7 A0A087WUN7 H0YJ07 ENST00000555890.5 ENST00000553981.1 ENST00000238688.9 [Q9GZT3-2] ENST00000557342.6 [Q9GZT3-1] G3V2S9 H0YJU7 G3V4X6 ENST00000557623.5 Q9GZT3 ENST00000556310.1 ENST00000557431.5

SLIRP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review