SH3BGRL3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	45 studies	72% ± 24%	Explore
B cell	44 studies	68% ± 21%	Explore
natural killer cell	43 studies	78% ± 18%	Explore
T cell	39 studies	69% ± 24%	Explore
endothelial cell	39 studies	55% ± 23%	Explore
CD8-positive, alpha-beta T cell	39 studies	80% ± 19%	Explore
fibroblast	35 studies	45% ± 15%	Explore
CD4-positive, alpha-beta T cell	35 studies	76% ± 22%	Explore
conventional dendritic cell	30 studies	89% ± 13%	Explore
classical monocyte	29 studies	91% ± 16%	Explore
pericyte	28 studies	42% ± 18%	Explore
dendritic cell	27 studies	75% ± 22%	Explore
monocyte	27 studies	80% ± 24%	Explore
regulatory T cell	27 studies	85% ± 14%	Explore
plasmacytoid dendritic cell	26 studies	86% ± 12%	Explore
non-classical monocyte	25 studies	95% ± 9%	Explore
mast cell	24 studies	70% ± 24%	Explore
epithelial cell	23 studies	58% ± 27%	Explore
plasma cell	21 studies	55% ± 23%	Explore
smooth muscle cell	21 studies	37% ± 11%	Explore
mature NK T cell	21 studies	83% ± 17%	Explore
endothelial cell of lymphatic vessel	20 studies	77% ± 14%	Explore
gamma-delta T cell	20 studies	82% ± 20%	Explore
memory B cell	20 studies	80% ± 11%	Explore
basal cell	20 studies	61% ± 18%	Explore
naive B cell	19 studies	73% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	71% ± 19%	Explore
connective tissue cell	17 studies	52% ± 18%	Explore
mucosal invariant T cell	16 studies	86% ± 17%	Explore
neutrophil	16 studies	70% ± 21%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	78% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	89% ± 11%	Explore
ciliated cell	15 studies	44% ± 20%	Explore
capillary endothelial cell	15 studies	48% ± 20%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	88% ± 10%	Explore
endothelial cell of artery	14 studies	58% ± 21%	Explore
myeloid cell	14 studies	79% ± 24%	Explore
myofibroblast cell	13 studies	42% ± 14%	Explore
goblet cell	13 studies	64% ± 30%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	80% ± 21%	Explore
innate lymphoid cell	12 studies	75% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	86% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	88% ± 13%	Explore
vein endothelial cell	12 studies	63% ± 20%	Explore
plasmablast	11 studies	76% ± 21%	Explore
platelet	11 studies	85% ± 23%	Explore
secretory cell	11 studies	55% ± 27%	Explore
endothelial cell of vascular tree	11 studies	67% ± 22%	Explore
T follicular helper cell	10 studies	78% ± 16%	Explore
progenitor cell	9 studies	52% ± 24%	Explore
type I pneumocyte	8 studies	26% ± 7%	Explore
type II pneumocyte	8 studies	30% ± 9%	Explore
erythrocyte	8 studies	51% ± 25%	Explore
leukocyte	8 studies	81% ± 9%	Explore
mononuclear phagocyte	8 studies	71% ± 28%	Explore
abnormal cell	8 studies	62% ± 19%	Explore
mesothelial cell	8 studies	43% ± 16%	Explore
hematopoietic stem cell	8 studies	89% ± 8%	Explore
alveolar macrophage	7 studies	74% ± 31%	Explore
club cell	7 studies	43% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	7 studies	82% ± 23%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	91% ± 14%	Explore
neuron	7 studies	42% ± 19%	Explore
enterocyte	7 studies	50% ± 18%	Explore
IgG plasma cell	7 studies	34% ± 21%	Explore
hematopoietic precursor cell	6 studies	73% ± 21%	Explore
respiratory goblet cell	6 studies	43% ± 20%	Explore
epithelial cell of proximal tubule	6 studies	31% ± 9%	Explore
kidney loop of Henle epithelial cell	6 studies	26% ± 5%	Explore
megakaryocyte	6 studies	82% ± 27%	Explore
IgA plasma cell	6 studies	34% ± 23%	Explore
precursor B cell	6 studies	83% ± 9%	Explore
immature B cell	6 studies	82% ± 11%	Explore
intermediate monocyte	6 studies	93% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	89% ± 10%	Explore
CD4-positive helper T cell	5 studies	77% ± 11%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	90% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	92% ± 6%	Explore
exhausted T cell	5 studies	96% ± 3%	Explore
oligodendrocyte	5 studies	24% ± 4%	Explore
transit amplifying cell	5 studies	47% ± 16%	Explore
pro-B cell	5 studies	78% ± 25%	Explore
T-helper 17 cell	5 studies	91% ± 7%	Explore
group 3 innate lymphoid cell	5 studies	83% ± 8%	Explore
microglial cell	5 studies	53% ± 20%	Explore
double negative thymocyte	5 studies	91% ± 5%	Explore
granulocyte	5 studies	87% ± 8%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	82% ± 26%	Explore
squamous epithelial cell	4 studies	48% ± 23%	Explore
pancreatic A cell	4 studies	56% ± 21%	Explore
type B pancreatic cell	4 studies	41% ± 19%	Explore
glomerular endothelial cell	4 studies	48% ± 14%	Explore
enteroendocrine cell	4 studies	66% ± 7%	Explore
intestinal crypt stem cell	4 studies	41% ± 13%	Explore
retinal ganglion cell	4 studies	73% ± 26%	Explore
erythroblast	4 studies	42% ± 11%	Explore
lymphocyte	4 studies	84% ± 12%	Explore
adventitial cell	4 studies	61% ± 11%	Explore
mucus secreting cell	4 studies	35% ± 2%	Explore
inflammatory macrophage	4 studies	75% ± 13%	Explore
germinal center B cell	4 studies	65% ± 23%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	42% ± 2%	Explore
T-helper 1 cell	4 studies	95% ± 6%	Explore
duct epithelial cell	3 studies	33% ± 9%	Explore
ionocyte	3 studies	37% ± 4%	Explore
monocyte-derived dendritic cell	3 studies	84% ± 20%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	29% ± 1%	Explore
renal alpha-intercalated cell	3 studies	39% ± 6%	Explore
neural crest cell	3 studies	28% ± 2%	Explore
thymocyte	3 studies	70% ± 11%	Explore
extravillous trophoblast	3 studies	68% ± 8%	Explore
placental villous trophoblast	3 studies	24% ± 5%	Explore
brush cell	3 studies	41% ± 18%	Explore
neuroendocrine cell	3 studies	65% ± 22%	Explore
serous secreting cell	3 studies	54% ± 4%	Explore
tissue-resident macrophage	3 studies	58% ± 26%	Explore
intraepithelial lymphocyte	3 studies	90% ± 4%	Explore
muscle cell	3 studies	26% ± 11%	Explore
myoepithelial cell	3 studies	38% ± 6%	Explore
luminal cell of prostate epithelium	3 studies	61% ± 11%	Explore
IgM plasma cell	3 studies	53% ± 24%	Explore
pancreatic ductal cell	3 studies	72% ± 13%	Explore
oligodendrocyte precursor cell	3 studies	27% ± 6%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	96% ± 1%	Explore
glial cell	3 studies	40% ± 16%	Explore
keratinocyte	3 studies	70% ± 15%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	94% ± 0%	Explore
double-positive, alpha-beta thymocyte	3 studies	88% ± 9%	Explore
progenitor cell of mammary luminal epithelium	3 studies	50% ± 14%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	20 studies	85% ± 12%	Explore
lung	18 studies	64% ± 13%	Explore
intestine	13 studies	49% ± 17%	Explore
kidney	9 studies	49% ± 24%	Explore
brain	7 studies	41% ± 18%	Explore
liver	6 studies	52% ± 23%	Explore
bone marrow	6 studies	65% ± 25%	Explore
lymph node	6 studies	73% ± 13%	Explore
pancreas	5 studies	50% ± 18%	Explore
eye	5 studies	27% ± 7%	Explore
placenta	5 studies	46% ± 15%	Explore
uterus	5 studies	54% ± 26%	Explore
prostate	4 studies	63% ± 20%	Explore
breast	4 studies	58% ± 12%	Explore
heart	3 studies	27% ± 9%	Explore
adrenal gland	3 studies	62% ± 24%	Explore
esophagus	3 studies	64% ± 18%	Explore
skin	3 studies	55% ± 22%	Explore
stomach	3 studies	33% ± 19%	Explore
thymus	3 studies	62% ± 27%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6961.10	1443 / 1445	100%	924.63	183 / 183
stomach	100%	4392.00	359 / 359	100%	830.26	285 / 286
skin	100%	11608.00	1809 / 1809	100%	802.06	470 / 472
intestine	99%	5683.23	959 / 966	100%	812.69	527 / 527
bladder	100%	6172.00	21 / 21	99%	743.88	500 / 504
breast	100%	6037.49	459 / 459	99%	431.72	1103 / 1118
lung	100%	8859.77	577 / 578	99%	640.37	1141 / 1155
thymus	99%	3761.66	647 / 653	99%	492.48	601 / 605
prostate	99%	3655.73	242 / 245	99%	274.80	498 / 502
uterus	99%	3360.25	168 / 170	99%	684.71	454 / 459
adrenal gland	99%	3907.82	256 / 258	96%	275.45	221 / 230
brain	95%	3744.70	2498 / 2642	100%	335.25	702 / 705
ovary	94%	2489.13	169 / 180	100%	707.62	430 / 430
kidney	99%	4274.17	88 / 89	94%	362.52	844 / 901
pancreas	91%	2782.59	299 / 328	98%	802.45	175 / 178
liver	53%	1443.69	120 / 226	79%	211.93	319 / 406
adipose	100%	7792.49	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	934.92	29 / 29
peripheral blood	100%	35761.64	929 / 929	0%	0	0 / 0
spleen	100%	10826.04	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	802.53	45 / 45
ureter	0%	0	0 / 0	100%	748.70	1 / 1
blood vessel	99%	7312.97	1328 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	486.53	79 / 80
heart	84%	2704.09	724 / 861	0%	0	0 / 0
muscle	15%	275.13	121 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007010	Biological process	cytoskeleton organization
GO_0032587	Cellular component	ruffle membrane
GO_0005737	Cellular component	cytoplasm
GO_0070062	Cellular component	extracellular exosome
GO_0016604	Cellular component	nuclear body
GO_0005829	Cellular component	cytosol
GO_0005515	Molecular function	protein binding
GO_0004364	Molecular function	glutathione transferase activity

Gene name	SH3BGRL3
Protein name	SH3 domain-binding glutamic acid-rich-like protein 3 SH3 domain-binding glutamic acid-rich-like protein 3 (SH3 domain-binding protein 1) (SH3BP-1) (TNF inhibitory protein B1) (TIP-B1)
Synonyms	P1725
Description	FUNCTION: Could act as a modulator of glutaredoxin biological activity (Probable). May play a role in cytoskeleton organization . .
Accessions	Q9H299 Q5T123 ENST00000319041.6 ENST00000270792.10

SH3BGRL3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review