RSL1D1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	36 studies	36% ± 10%	Explore
fibroblast	32 studies	36% ± 13%	Explore
CD4-positive, alpha-beta T cell	31 studies	40% ± 14%	Explore
natural killer cell	30 studies	28% ± 9%	Explore
CD8-positive, alpha-beta T cell	30 studies	34% ± 13%	Explore
T cell	28 studies	31% ± 11%	Explore
conventional dendritic cell	28 studies	43% ± 17%	Explore
macrophage	26 studies	27% ± 10%	Explore
classical monocyte	25 studies	34% ± 15%	Explore
regulatory T cell	24 studies	36% ± 10%	Explore
non-classical monocyte	23 studies	36% ± 17%	Explore
endothelial cell	22 studies	31% ± 12%	Explore
smooth muscle cell	22 studies	36% ± 12%	Explore
memory B cell	20 studies	42% ± 10%	Explore
plasmacytoid dendritic cell	20 studies	38% ± 13%	Explore
basal cell	20 studies	41% ± 15%	Explore
naive B cell	19 studies	37% ± 9%	Explore
pericyte	19 studies	37% ± 10%	Explore
mature NK T cell	18 studies	30% ± 12%	Explore
epithelial cell	17 studies	40% ± 22%	Explore
gamma-delta T cell	17 studies	36% ± 16%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	16 studies	46% ± 13%	Explore
dendritic cell	15 studies	45% ± 24%	Explore
monocyte	15 studies	33% ± 10%	Explore
connective tissue cell	15 studies	41% ± 13%	Explore
mast cell	14 studies	25% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	46% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	35% ± 11%	Explore
plasma cell	12 studies	35% ± 18%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	28% ± 14%	Explore
myofibroblast cell	12 studies	40% ± 14%	Explore
mucosal invariant T cell	12 studies	36% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	36% ± 13%	Explore
endothelial cell of vascular tree	11 studies	36% ± 11%	Explore
plasmablast	10 studies	38% ± 20%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	40% ± 16%	Explore
abnormal cell	10 studies	36% ± 12%	Explore
vein endothelial cell	10 studies	28% ± 11%	Explore
endothelial cell of lymphatic vessel	9 studies	30% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	38% ± 16%	Explore
progenitor cell	9 studies	49% ± 19%	Explore
myeloid cell	9 studies	35% ± 17%	Explore
secretory cell	8 studies	38% ± 16%	Explore
leukocyte	8 studies	30% ± 10%	Explore
hematopoietic stem cell	8 studies	61% ± 22%	Explore
club cell	7 studies	26% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	31% ± 9%	Explore
endothelial cell of artery	7 studies	21% ± 6%	Explore
mesothelial cell	7 studies	46% ± 18%	Explore
precursor B cell	7 studies	45% ± 17%	Explore
innate lymphoid cell	7 studies	31% ± 5%	Explore
immature B cell	7 studies	44% ± 14%	Explore
ciliated cell	7 studies	33% ± 14%	Explore
T follicular helper cell	7 studies	37% ± 8%	Explore
type II pneumocyte	6 studies	36% ± 18%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	38% ± 10%	Explore
goblet cell	6 studies	26% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	40% ± 13%	Explore
erythrocyte	6 studies	35% ± 19%	Explore
alveolar macrophage	5 studies	30% ± 4%	Explore
CD4-positive helper T cell	5 studies	27% ± 9%	Explore
hematopoietic precursor cell	5 studies	67% ± 25%	Explore
mononuclear phagocyte	5 studies	38% ± 16%	Explore
capillary endothelial cell	5 studies	30% ± 12%	Explore
intestinal crypt stem cell	5 studies	40% ± 10%	Explore
transit amplifying cell	5 studies	21% ± 3%	Explore
erythroblast	5 studies	48% ± 28%	Explore
pro-B cell	5 studies	40% ± 17%	Explore
neuron	5 studies	34% ± 13%	Explore
granulocyte	5 studies	28% ± 12%	Explore
type I pneumocyte	4 studies	39% ± 13%	Explore
pancreatic A cell	4 studies	37% ± 12%	Explore
exhausted T cell	4 studies	33% ± 6%	Explore
epithelial cell of proximal tubule	4 studies	29% ± 12%	Explore
enteroendocrine cell	4 studies	37% ± 15%	Explore
adventitial cell	4 studies	25% ± 12%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	41% ± 3%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	64% ± 28%	Explore
T-helper 17 cell	4 studies	38% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	26% ± 8%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	43% ± 14%	Explore
duct epithelial cell	3 studies	20% ± 3%	Explore
precursor cell	3 studies	53% ± 11%	Explore
type B pancreatic cell	3 studies	45% ± 13%	Explore
kidney loop of Henle epithelial cell	3 studies	20% ± 2%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	46% ± 22%	Explore
enterocyte	3 studies	33% ± 15%	Explore
neural crest cell	3 studies	57% ± 5%	Explore
extravillous trophoblast	3 studies	49% ± 6%	Explore
placental villous trophoblast	3 studies	41% ± 6%	Explore
common myeloid progenitor	3 studies	51% ± 24%	Explore
lymphocyte	3 studies	38% ± 11%	Explore
microglial cell	3 studies	23% ± 6%	Explore
serous secreting cell	3 studies	37% ± 6%	Explore
muscle cell	3 studies	30% ± 12%	Explore
germinal center B cell	3 studies	35% ± 1%	Explore
intermediate monocyte	3 studies	51% ± 16%	Explore
myoepithelial cell	3 studies	52% ± 12%	Explore
GABAergic neuron	3 studies	25% ± 6%	Explore
glutamatergic neuron	3 studies	33% ± 10%	Explore
pancreatic ductal cell	3 studies	39% ± 14%	Explore
granulocyte monocyte progenitor cell	3 studies	43% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	46% ± 13%	Explore
keratinocyte	3 studies	37% ± 7%	Explore
T-helper 1 cell	3 studies	47% ± 4%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	45% ± 11%	Explore
double negative thymocyte	3 studies	51% ± 21%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	43% ± 20%	Explore
progenitor cell of mammary luminal epithelium	3 studies	62% ± 18%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	19 studies	41% ± 17%	Explore
lung	16 studies	31% ± 12%	Explore
intestine	10 studies	31% ± 15%	Explore
kidney	6 studies	31% ± 9%	Explore
brain	6 studies	23% ± 3%	Explore
uterus	5 studies	39% ± 14%	Explore
lymph node	5 studies	38% ± 8%	Explore
liver	5 studies	30% ± 15%	Explore
pancreas	4 studies	38% ± 15%	Explore
bone marrow	4 studies	38% ± 22%	Explore
breast	4 studies	43% ± 8%	Explore
placenta	3 studies	38% ± 5%	Explore
eye	3 studies	30% ± 5%	Explore
skin	3 studies	27% ± 5%	Explore
prostate	3 studies	36% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	8847.04	459 / 459	100%	133.30	1118 / 1118
ovary	100%	14761.18	180 / 180	100%	96.06	430 / 430
pancreas	100%	6698.78	328 / 328	100%	76.98	178 / 178
prostate	100%	6230.62	245 / 245	100%	109.09	502 / 502
stomach	100%	5263.33	359 / 359	100%	99.16	286 / 286
esophagus	100%	5918.59	1444 / 1445	100%	79.42	183 / 183
bladder	100%	7451.29	21 / 21	100%	96.53	503 / 504
uterus	100%	7927.90	170 / 170	100%	98.37	458 / 459
intestine	100%	6376.30	965 / 966	100%	108.45	526 / 527
thymus	100%	4998.43	653 / 653	100%	84.37	603 / 605
lung	99%	5200.02	575 / 578	100%	93.97	1155 / 1155
kidney	100%	4357.38	89 / 89	99%	79.24	895 / 901
skin	100%	9577.29	1809 / 1809	99%	110.19	468 / 472
liver	100%	3188.88	225 / 226	99%	51.98	403 / 406
adrenal gland	100%	5768.32	258 / 258	98%	66.15	226 / 230
brain	98%	3595.99	2587 / 2642	100%	73.29	705 / 705
adipose	100%	9230.56	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	133.48	29 / 29
muscle	100%	13874.59	803 / 803	0%	0	0 / 0
spleen	100%	5326.76	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	80.33	45 / 45
ureter	0%	0	0 / 0	100%	46.38	1 / 1
blood vessel	100%	6109.44	1334 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	98%	116.41	78 / 80
heart	96%	4201.78	824 / 861	0%	0	0 / 0
peripheral blood	93%	5887.89	866 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0032880	Biological process	regulation of protein localization
GO_0001649	Biological process	osteoblast differentiation
GO_0042981	Biological process	regulation of apoptotic process
GO_2000772	Biological process	regulation of cellular senescence
GO_0000462	Biological process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0005730	Cellular component	nucleolus
GO_0005694	Cellular component	chromosome
GO_0016020	Cellular component	membrane
GO_0045296	Molecular function	cadherin binding
GO_0003730	Molecular function	mRNA 3'-UTR binding
GO_0048027	Molecular function	mRNA 5'-UTR binding
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	RSL1D1
Protein name	Ribosomal L1 domain containing 1 Large ribosomal subunit protein uL1 Ribosomal L1 domain-containing protein 1 (CATX-11) (Cellular senescence-inhibited gene protein) (Protein PBK1) RSL1D1 protein
Synonyms	CSIG PBK1 L12 CATX11
Description	FUNCTION: Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage. .
Accessions	A0PJ61 ENST00000571988.5 I3L3U9 Q32Q62 ENST00000572090.5 ENST00000573791.1 ENST00000573251.5 ENST00000396503.7 I3L1Y4 J3QSV6 I3L4T8 ENST00000571133.6 [O76021-1] ENST00000573029.1 A0PJ87 O76021 I3L234 J3KPU7 ENST00000355674.9 ENST00000573618.5 ENST00000570767.5 I3L3C4 I3L2F2 I3L1A3

RSL1D1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review