PDCD5 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	31 studies	30% ± 13%	Explore
endothelial cell	26 studies	29% ± 12%	Explore
smooth muscle cell	23 studies	28% ± 8%	Explore
CD4-positive, alpha-beta T cell	22 studies	32% ± 18%	Explore
pericyte	21 studies	29% ± 9%	Explore
natural killer cell	20 studies	24% ± 12%	Explore
basal cell	20 studies	32% ± 16%	Explore
T cell	19 studies	25% ± 8%	Explore
CD8-positive, alpha-beta T cell	19 studies	34% ± 17%	Explore
regulatory T cell	18 studies	30% ± 14%	Explore
B cell	16 studies	21% ± 5%	Explore
epithelial cell	16 studies	39% ± 19%	Explore
connective tissue cell	15 studies	31% ± 8%	Explore
endothelial cell of lymphatic vessel	14 studies	30% ± 10%	Explore
non-classical monocyte	14 studies	31% ± 14%	Explore
conventional dendritic cell	14 studies	28% ± 15%	Explore
macrophage	13 studies	24% ± 10%	Explore
plasma cell	12 studies	37% ± 14%	Explore
ciliated cell	12 studies	34% ± 17%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	24% ± 6%	Explore
mature NK T cell	12 studies	22% ± 6%	Explore
gamma-delta T cell	12 studies	24% ± 15%	Explore
classical monocyte	11 studies	25% ± 10%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	26% ± 8%	Explore
vein endothelial cell	11 studies	25% ± 6%	Explore
endothelial cell of vascular tree	11 studies	28% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	20% ± 4%	Explore
capillary endothelial cell	10 studies	22% ± 7%	Explore
myofibroblast cell	10 studies	30% ± 6%	Explore
endothelial cell of artery	10 studies	22% ± 3%	Explore
secretory cell	9 studies	30% ± 17%	Explore
mucosal invariant T cell	9 studies	22% ± 5%	Explore
plasmablast	8 studies	51% ± 23%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	30% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	28% ± 11%	Explore
monocyte	8 studies	22% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	27% ± 6%	Explore
progenitor cell	8 studies	32% ± 12%	Explore
memory B cell	8 studies	25% ± 11%	Explore
type I pneumocyte	7 studies	29% ± 13%	Explore
club cell	7 studies	28% ± 11%	Explore
naive B cell	7 studies	20% ± 4%	Explore
abnormal cell	7 studies	43% ± 15%	Explore
neuron	7 studies	35% ± 16%	Explore
myeloid cell	7 studies	29% ± 12%	Explore
plasmacytoid dendritic cell	7 studies	25% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	37% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	24% ± 4%	Explore
goblet cell	6 studies	23% ± 11%	Explore
mesothelial cell	6 studies	33% ± 17%	Explore
dendritic cell	6 studies	51% ± 24%	Explore
hematopoietic precursor cell	5 studies	36% ± 15%	Explore
leukocyte	5 studies	23% ± 8%	Explore
kidney loop of Henle epithelial cell	5 studies	22% ± 3%	Explore
epithelial cell of proximal tubule	5 studies	24% ± 8%	Explore
intestinal crypt stem cell	5 studies	25% ± 9%	Explore
transit amplifying cell	5 studies	23% ± 4%	Explore
hematopoietic stem cell	5 studies	27% ± 12%	Explore
type II pneumocyte	5 studies	36% ± 15%	Explore
astrocyte	5 studies	22% ± 10%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	37% ± 15%	Explore
pancreatic A cell	4 studies	45% ± 16%	Explore
type B pancreatic cell	4 studies	39% ± 15%	Explore
exhausted T cell	4 studies	33% ± 13%	Explore
enterocyte	4 studies	20% ± 2%	Explore
enteroendocrine cell	4 studies	36% ± 12%	Explore
retinal ganglion cell	4 studies	50% ± 29%	Explore
erythroblast	4 studies	34% ± 7%	Explore
adventitial cell	4 studies	25% ± 4%	Explore
T follicular helper cell	4 studies	21% ± 2%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	43% ± 7%	Explore
innate lymphoid cell	4 studies	19% ± 1%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	30% ± 8%	Explore
glutamatergic neuron	4 studies	37% ± 16%	Explore
oligodendrocyte precursor cell	4 studies	26% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	21% ± 6%	Explore
duct epithelial cell	3 studies	17% ± 3%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	30% ± 5%	Explore
renal alpha-intercalated cell	3 studies	29% ± 1%	Explore
neural crest cell	3 studies	34% ± 3%	Explore
extravillous trophoblast	3 studies	26% ± 3%	Explore
placental villous trophoblast	3 studies	42% ± 11%	Explore
common myeloid progenitor	3 studies	35% ± 12%	Explore
lymphocyte	3 studies	39% ± 7%	Explore
amacrine cell	3 studies	41% ± 12%	Explore
retina horizontal cell	3 studies	32% ± 13%	Explore
mucus secreting cell	3 studies	22% ± 0%	Explore
serous secreting cell	3 studies	29% ± 6%	Explore
muscle cell	3 studies	32% ± 17%	Explore
intermediate monocyte	3 studies	36% ± 12%	Explore
GABAergic neuron	3 studies	36% ± 7%	Explore
granulocyte monocyte progenitor cell	3 studies	39% ± 8%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	50% ± 18%	Explore
keratinocyte	3 studies	24% ± 4%	Explore
T-helper 17 cell	3 studies	39% ± 30%	Explore
T-helper 1 cell	3 studies	35% ± 18%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	27% ± 8%	Explore
double negative thymocyte	3 studies	36% ± 17%	Explore
progenitor cell of mammary luminal epithelium	3 studies	26% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	13 studies	30% ± 14%	Explore
peripheral blood	13 studies	27% ± 8%	Explore
kidney	7 studies	23% ± 4%	Explore
intestine	7 studies	26% ± 11%	Explore
brain	7 studies	26% ± 10%	Explore
eye	6 studies	23% ± 10%	Explore
liver	5 studies	25% ± 13%	Explore
pancreas	4 studies	42% ± 15%	Explore
placenta	4 studies	29% ± 9%	Explore
bone marrow	4 studies	22% ± 6%	Explore
uterus	4 studies	36% ± 14%	Explore
prostate	4 studies	24% ± 8%	Explore
lymph node	4 studies	29% ± 13%	Explore
breast	4 studies	27% ± 3%	Explore
adrenal gland	3 studies	22% ± 2%	Explore
skin	3 studies	21% ± 3%	Explore
thymus	3 studies	37% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	3297.65	258 / 258	100%	89.01	230 / 230
bladder	100%	3352.90	21 / 21	100%	110.55	504 / 504
esophagus	100%	3367.07	1445 / 1445	100%	69.62	183 / 183
liver	100%	1875.83	226 / 226	100%	67.40	406 / 406
ovary	100%	3311.07	180 / 180	100%	105.26	430 / 430
pancreas	100%	1855.14	328 / 328	100%	67.70	178 / 178
uterus	100%	3260.12	170 / 170	100%	124.55	459 / 459
brain	100%	3090.64	2640 / 2642	100%	64.92	705 / 705
thymus	100%	2836.55	653 / 653	100%	57.80	604 / 605
intestine	100%	3053.92	966 / 966	100%	100.32	526 / 527
stomach	100%	2262.82	359 / 359	100%	92.29	285 / 286
breast	100%	3209.91	459 / 459	100%	79.99	1114 / 1118
prostate	100%	2810.99	245 / 245	100%	61.92	500 / 502
lung	99%	3073.93	575 / 578	100%	93.24	1154 / 1155
kidney	100%	2648.70	89 / 89	99%	59.16	893 / 901
skin	100%	3287.03	1809 / 1809	98%	66.01	463 / 472
adipose	100%	3260.31	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	93.69	29 / 29
muscle	100%	3398.07	803 / 803	0%	0	0 / 0
spleen	100%	2440.30	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	95.28	45 / 45
ureter	0%	0	0 / 0	100%	62.27	1 / 1
blood vessel	100%	3223.02	1333 / 1335	0%	0	0 / 0
heart	99%	3258.21	855 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	89%	34.37	71 / 80
peripheral blood	49%	1409.24	456 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0090200	Biological process	positive regulation of release of cytochrome c from mitochondria
GO_0006915	Biological process	apoptotic process
GO_0010628	Biological process	positive regulation of gene expression
GO_0008285	Biological process	negative regulation of cell population proliferation
GO_0071560	Biological process	cellular response to transforming growth factor beta stimulus
GO_0043065	Biological process	positive regulation of apoptotic process
GO_1903645	Biological process	negative regulation of chaperone-mediated protein folding
GO_0043280	Biological process	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO_1903638	Biological process	positive regulation of protein insertion into mitochondrial outer membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0010698	Molecular function	acetyltransferase activator activity
GO_0003677	Molecular function	DNA binding
GO_0008201	Molecular function	heparin binding
GO_0048487	Molecular function	beta-tubulin binding
GO_0005515	Molecular function	protein binding

Gene name	PDCD5
Protein name	Programmed cell death protein 5 (TF-1 cell apoptosis-related protein 19) (Protein TFAR19) Programmed cell death 5
Synonyms	TFAR19
Description	FUNCTION: May function in the process of apoptosis.
Accessions	K7ESJ4 ENST00000221784.8 ENST00000586035.1 ENST00000592786.5 ENST00000379316.3 ENST00000590247.7 [O14737-1] X6R2P6 O14737 K7EQA1 ENST00000419343.7 [O14737-2] Q3HM38

PDCD5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review