Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 16 studies | 38% ± 13% | |
| peripheral blood | 15 studies | 33% ± 10% | |
| intestine | 12 studies | 33% ± 18% | |
| kidney | 9 studies | 37% ± 11% | |
| eye | 7 studies | 36% ± 18% | |
| brain | 7 studies | 26% ± 7% | |
| liver | 7 studies | 36% ± 21% | |
| bone marrow | 5 studies | 26% ± 9% | |
| lymph node | 5 studies | 36% ± 19% | |
| pancreas | 4 studies | 50% ± 20% | |
| uterus | 4 studies | 41% ± 15% | |
| breast | 4 studies | 30% ± 4% | |
| placenta | 3 studies | 41% ± 18% | |
| adrenal gland | 3 studies | 29% ± 9% | |
| prostate | 3 studies | 22% ± 5% | |
| thymus | 3 studies | 50% ± 24% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2320.19 | 1445 / 1445 | 100% | 190.26 | 183 / 183 |
| liver | 100% | 2045.40 | 226 / 226 | 100% | 297.45 | 406 / 406 |
| ovary | 100% | 1237.82 | 180 / 180 | 100% | 265.49 | 430 / 430 |
| pancreas | 100% | 1212.42 | 328 / 328 | 100% | 212.28 | 178 / 178 |
| brain | 100% | 1916.38 | 2637 / 2642 | 100% | 202.00 | 705 / 705 |
| uterus | 100% | 1640.68 | 170 / 170 | 100% | 393.40 | 458 / 459 |
| skin | 100% | 1951.20 | 1808 / 1809 | 100% | 234.93 | 471 / 472 |
| thymus | 100% | 1896.78 | 652 / 653 | 100% | 218.32 | 604 / 605 |
| stomach | 100% | 1889.38 | 359 / 359 | 99% | 237.75 | 284 / 286 |
| intestine | 100% | 2405.67 | 966 / 966 | 99% | 280.74 | 523 / 527 |
| prostate | 100% | 1962.60 | 245 / 245 | 99% | 271.78 | 498 / 502 |
| adrenal gland | 100% | 2099.18 | 258 / 258 | 99% | 229.60 | 228 / 230 |
| kidney | 100% | 2774.11 | 89 / 89 | 99% | 169.04 | 891 / 901 |
| lung | 100% | 1671.94 | 576 / 578 | 99% | 265.02 | 1141 / 1155 |
| bladder | 100% | 1915.29 | 21 / 21 | 98% | 316.25 | 496 / 504 |
| breast | 100% | 1901.65 | 459 / 459 | 98% | 212.69 | 1092 / 1118 |
| adipose | 100% | 1884.37 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 294.39 | 80 / 80 |
| heart | 100% | 4931.29 | 861 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 432.24 | 29 / 29 |
| muscle | 100% | 3877.63 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1911.53 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 335.37 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 350.98 | 1 / 1 |
| blood vessel | 100% | 1829.19 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 90% | 1214.02 | 840 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0009060 | Biological process | aerobic respiration |
| GO_0006120 | Biological process | mitochondrial electron transport, NADH to ubiquinone |
| GO_0042776 | Biological process | proton motive force-driven mitochondrial ATP synthesis |
| GO_0055085 | Biological process | transmembrane transport |
| GO_0045271 | Cellular component | respiratory chain complex I |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0008137 | Molecular function | NADH dehydrogenase (ubiquinone) activity |
| GO_0009055 | Molecular function | electron transfer activity |
| Gene name | NDUFS6 |
| Protein name | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NADH:ubiquinone oxidoreductase subunit S6 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Complex I-13kD-A) (CI-13kD-A) (NADH-ubiquinone oxidoreductase 13 kDa-A subunit) |
| Synonyms | hCG_21432 |
| Description | FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . |
| Accessions | D6RBT3 ENST00000274137.10 Q6IBC4 O75380 ENST00000469176.1 |