NDUFA5 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	29 studies	22% ± 6%	Explore
fibroblast	29 studies	28% ± 12%	Explore
B cell	25 studies	22% ± 8%	Explore
endothelial cell	24 studies	28% ± 11%	Explore
pericyte	23 studies	30% ± 10%	Explore
smooth muscle cell	22 studies	32% ± 9%	Explore
CD4-positive, alpha-beta T cell	21 studies	22% ± 7%	Explore
T cell	19 studies	23% ± 10%	Explore
CD8-positive, alpha-beta T cell	18 studies	23% ± 7%	Explore
epithelial cell	18 studies	38% ± 21%	Explore
regulatory T cell	17 studies	22% ± 4%	Explore
naive B cell	15 studies	20% ± 5%	Explore
basal cell	14 studies	32% ± 17%	Explore
ciliated cell	14 studies	39% ± 16%	Explore
memory B cell	14 studies	20% ± 4%	Explore
myofibroblast cell	13 studies	28% ± 9%	Explore
gamma-delta T cell	13 studies	26% ± 13%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	21% ± 4%	Explore
mature NK T cell	12 studies	23% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	23% ± 5%	Explore
connective tissue cell	11 studies	32% ± 11%	Explore
endothelial cell of lymphatic vessel	10 studies	27% ± 7%	Explore
secretory cell	10 studies	27% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	24% ± 5%	Explore
non-classical monocyte	9 studies	29% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	24% ± 6%	Explore
capillary endothelial cell	9 studies	20% ± 3%	Explore
mucosal invariant T cell	9 studies	23% ± 5%	Explore
astrocyte	9 studies	33% ± 16%	Explore
mast cell	8 studies	20% ± 4%	Explore
abnormal cell	8 studies	34% ± 15%	Explore
neuron	8 studies	41% ± 18%	Explore
mesothelial cell	8 studies	33% ± 15%	Explore
glutamatergic neuron	8 studies	38% ± 23%	Explore
endothelial cell of vascular tree	8 studies	22% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	26% ± 6%	Explore
platelet	7 studies	23% ± 5%	Explore
conventional dendritic cell	7 studies	28% ± 16%	Explore
epithelial cell of proximal tubule	7 studies	48% ± 11%	Explore
progenitor cell	7 studies	33% ± 6%	Explore
endothelial cell of artery	7 studies	22% ± 4%	Explore
goblet cell	7 studies	28% ± 14%	Explore
retinal rod cell	7 studies	41% ± 21%	Explore
plasmacytoid dendritic cell	7 studies	25% ± 10%	Explore
type I pneumocyte	6 studies	29% ± 10%	Explore
plasma cell	6 studies	31% ± 12%	Explore
club cell	6 studies	28% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	29% ± 9%	Explore
kidney loop of Henle epithelial cell	6 studies	56% ± 11%	Explore
renal alpha-intercalated cell	6 studies	70% ± 17%	Explore
macrophage	6 studies	24% ± 9%	Explore
enterocyte	6 studies	28% ± 5%	Explore
retinal cone cell	6 studies	56% ± 29%	Explore
innate lymphoid cell	6 studies	23% ± 3%	Explore
T follicular helper cell	6 studies	22% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	23% ± 7%	Explore
GABAergic neuron	6 studies	35% ± 14%	Explore
ionocyte	5 studies	36% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	21% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	60% ± 8%	Explore
retinal ganglion cell	5 studies	65% ± 30%	Explore
precursor B cell	5 studies	32% ± 12%	Explore
pro-B cell	5 studies	30% ± 5%	Explore
type II pneumocyte	5 studies	30% ± 15%	Explore
cardiac muscle cell	5 studies	28% ± 7%	Explore
oligodendrocyte precursor cell	5 studies	26% ± 5%	Explore
pancreatic A cell	4 studies	62% ± 8%	Explore
type B pancreatic cell	4 studies	59% ± 19%	Explore
classical monocyte	4 studies	27% ± 9%	Explore
leukocyte	4 studies	23% ± 5%	Explore
exhausted T cell	4 studies	23% ± 5%	Explore
enteroendocrine cell	4 studies	40% ± 19%	Explore
intestinal crypt stem cell	4 studies	29% ± 7%	Explore
vein endothelial cell	4 studies	21% ± 1%	Explore
OFF-bipolar cell	4 studies	47% ± 28%	Explore
ON-bipolar cell	4 studies	46% ± 28%	Explore
myeloid cell	4 studies	24% ± 10%	Explore
brush cell	4 studies	33% ± 18%	Explore
immature B cell	4 studies	21% ± 5%	Explore
amacrine cell	4 studies	58% ± 21%	Explore
retina horizontal cell	4 studies	49% ± 19%	Explore
monocyte	4 studies	20% ± 4%	Explore
Mueller cell	4 studies	43% ± 18%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	27% ± 11%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	38% ± 3%	Explore
transit amplifying cell	4 studies	20% ± 3%	Explore
interneuron	4 studies	36% ± 16%	Explore
hematopoietic stem cell	4 studies	19% ± 1%	Explore
hematopoietic precursor cell	3 studies	32% ± 15%	Explore
plasmablast	3 studies	56% ± 6%	Explore
duct epithelial cell	3 studies	24% ± 0%	Explore
respiratory goblet cell	3 studies	28% ± 17%	Explore
pancreatic D cell	3 studies	59% ± 16%	Explore
neural crest cell	3 studies	28% ± 0%	Explore
retinal bipolar neuron	3 studies	64% ± 21%	Explore
microglial cell	3 studies	17% ± 1%	Explore
GABAergic amacrine cell	3 studies	36% ± 13%	Explore
glycinergic amacrine cell	3 studies	29% ± 11%	Explore
renal principal cell	3 studies	64% ± 7%	Explore
neuroendocrine cell	3 studies	36% ± 16%	Explore
retinal pigment epithelial cell	3 studies	38% ± 22%	Explore
rod bipolar cell	3 studies	46% ± 17%	Explore
erythroblast	3 studies	37% ± 23%	Explore
myoepithelial cell	3 studies	30% ± 8%	Explore
pancreatic ductal cell	3 studies	54% ± 11%	Explore
glial cell	3 studies	29% ± 19%	Explore
group 3 innate lymphoid cell	3 studies	29% ± 10%	Explore
keratinocyte	3 studies	19% ± 2%	Explore
T-helper 17 cell	3 studies	24% ± 6%	Explore
oligodendrocyte	3 studies	21% ± 1%	Explore
erythrocyte	3 studies	32% ± 22%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	22% ± 4%	Explore
double negative thymocyte	3 studies	36% ± 16%	Explore
hepatocyte	3 studies	39% ± 28%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	15 studies	28% ± 13%	Explore
peripheral blood	13 studies	25% ± 9%	Explore
intestine	10 studies	26% ± 12%	Explore
eye	10 studies	38% ± 20%	Explore
kidney	9 studies	33% ± 9%	Explore
brain	7 studies	35% ± 15%	Explore
lymph node	5 studies	24% ± 6%	Explore
pancreas	4 studies	53% ± 17%	Explore
bone marrow	4 studies	17% ± 1%	Explore
uterus	4 studies	35% ± 15%	Explore
breast	4 studies	22% ± 2%	Explore
liver	4 studies	30% ± 23%	Explore
placenta	3 studies	22% ± 5%	Explore
adrenal gland	3 studies	23% ± 2%	Explore
thymus	3 studies	38% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	5854.09	258 / 258	100%	34.89	230 / 230
kidney	100%	5429.54	89 / 89	100%	26.48	901 / 901
ovary	100%	2651.43	180 / 180	100%	17.24	430 / 430
uterus	100%	2946.10	170 / 170	100%	15.22	459 / 459
brain	100%	7172.84	2640 / 2642	100%	25.95	705 / 705
esophagus	100%	3986.07	1443 / 1445	100%	13.42	183 / 183
thymus	100%	5019.15	652 / 653	100%	27.26	604 / 605
prostate	100%	3490.40	244 / 245	100%	22.80	502 / 502
breast	100%	2825.59	459 / 459	99%	20.64	1112 / 1118
bladder	100%	3021.52	21 / 21	99%	13.60	498 / 504
lung	99%	2411.05	570 / 578	100%	14.42	1154 / 1155
liver	100%	2583.64	226 / 226	98%	11.21	397 / 406
stomach	100%	3438.01	359 / 359	97%	14.45	277 / 286
intestine	100%	4150.48	965 / 966	96%	13.99	505 / 527
skin	97%	1963.01	1758 / 1809	96%	14.66	453 / 472
pancreas	93%	1461.50	306 / 328	99%	13.59	176 / 178
lymph node	0%	0	0 / 0	100%	10.99	29 / 29
muscle	100%	8224.83	803 / 803	0%	0	0 / 0
spleen	100%	1960.17	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	5.57	1 / 1
blood vessel	100%	3198.64	1330 / 1335	0%	0	0 / 0
adipose	100%	2515.28	1198 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	11.66	44 / 45
heart	97%	7478.17	835 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	85%	9.32	68 / 80
peripheral blood	21%	750.57	191 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0009060	Biological process	aerobic respiration
GO_0022904	Biological process	respiratory electron transport chain
GO_0006120	Biological process	mitochondrial electron transport, NADH to ubiquinone
GO_0042776	Biological process	proton motive force-driven mitochondrial ATP synthesis
GO_0055085	Biological process	transmembrane transport
GO_0032981	Biological process	mitochondrial respiratory chain complex I assembly
GO_0045271	Cellular component	respiratory chain complex I
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0008137	Molecular function	NADH dehydrogenase (ubiquinone) activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	NDUFA5
Protein name	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (CI-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit)
Synonyms	hCG_1778942
Description	FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. .
Accessions	ENST00000677251.1 ENST00000471770.5 [Q16718-2] A0A087X1G1 A0A7I2V2W4 ENST00000678090.1 A0A7I2V3L8 ENST00000677391.1 ENST00000466896.5 A0A087WXR5 ENST00000676516.1 ENST00000679052.1 ENST00000679163.1 ENST00000470123.2 ENST00000677264.1 ENST00000676730.1 H7BYD0 Q16718 ENST00000355749.7 [Q16718-1] ENST00000676614.1 A0A024R772 ENST00000611607.4 ENST00000378795.9 ENST00000618945.4 C9IZN5 F8WAS3

NDUFA5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review