DYNLRB1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	36 studies	39% ± 16%	Explore
natural killer cell	32 studies	30% ± 10%	Explore
fibroblast	32 studies	37% ± 13%	Explore
macrophage	28 studies	33% ± 13%	Explore
CD8-positive, alpha-beta T cell	28 studies	32% ± 12%	Explore
CD4-positive, alpha-beta T cell	27 studies	30% ± 11%	Explore
pericyte	26 studies	43% ± 14%	Explore
B cell	25 studies	27% ± 9%	Explore
T cell	24 studies	28% ± 8%	Explore
regulatory T cell	24 studies	35% ± 12%	Explore
smooth muscle cell	23 studies	43% ± 13%	Explore
conventional dendritic cell	20 studies	30% ± 15%	Explore
non-classical monocyte	19 studies	32% ± 16%	Explore
epithelial cell	19 studies	45% ± 24%	Explore
mast cell	17 studies	31% ± 12%	Explore
monocyte	17 studies	26% ± 7%	Explore
basal cell	17 studies	35% ± 17%	Explore
ciliated cell	17 studies	60% ± 22%	Explore
connective tissue cell	17 studies	36% ± 12%	Explore
endothelial cell of lymphatic vessel	16 studies	47% ± 13%	Explore
classical monocyte	16 studies	31% ± 13%	Explore
memory B cell	15 studies	24% ± 5%	Explore
gamma-delta T cell	15 studies	29% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	30% ± 10%	Explore
plasmacytoid dendritic cell	13 studies	30% ± 12%	Explore
mature NK T cell	13 studies	31% ± 7%	Explore
myofibroblast cell	13 studies	43% ± 13%	Explore
naive B cell	12 studies	22% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	26% ± 7%	Explore
capillary endothelial cell	12 studies	36% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	30% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	29% ± 10%	Explore
endothelial cell of artery	11 studies	40% ± 14%	Explore
vein endothelial cell	11 studies	36% ± 13%	Explore
dendritic cell	11 studies	37% ± 24%	Explore
plasma cell	10 studies	40% ± 12%	Explore
plasmablast	10 studies	40% ± 24%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	32% ± 13%	Explore
secretory cell	10 studies	34% ± 15%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	32% ± 9%	Explore
abnormal cell	10 studies	44% ± 19%	Explore
endothelial cell of vascular tree	10 studies	40% ± 8%	Explore
myeloid cell	10 studies	36% ± 13%	Explore
type I pneumocyte	9 studies	48% ± 16%	Explore
goblet cell	9 studies	35% ± 16%	Explore
platelet	8 studies	28% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	30% ± 13%	Explore
neuron	8 studies	53% ± 23%	Explore
oligodendrocyte	8 studies	26% ± 11%	Explore
mesothelial cell	8 studies	41% ± 18%	Explore
glutamatergic neuron	8 studies	31% ± 18%	Explore
mucosal invariant T cell	8 studies	24% ± 4%	Explore
type II pneumocyte	7 studies	43% ± 18%	Explore
epithelial cell of proximal tubule	7 studies	49% ± 14%	Explore
progenitor cell	7 studies	27% ± 11%	Explore
astrocyte	7 studies	32% ± 17%	Explore
enterocyte	7 studies	28% ± 10%	Explore
T follicular helper cell	7 studies	30% ± 7%	Explore
alveolar macrophage	6 studies	35% ± 13%	Explore
ionocyte	6 studies	41% ± 12%	Explore
leukocyte	6 studies	28% ± 7%	Explore
kidney loop of Henle epithelial cell	6 studies	43% ± 7%	Explore
renal alpha-intercalated cell	6 studies	58% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	34% ± 15%	Explore
hematopoietic precursor cell	5 studies	38% ± 16%	Explore
club cell	5 studies	41% ± 15%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	39% ± 8%	Explore
mononuclear phagocyte	5 studies	29% ± 16%	Explore
enteroendocrine cell	5 studies	47% ± 19%	Explore
retinal ganglion cell	5 studies	71% ± 31%	Explore
microglial cell	5 studies	26% ± 9%	Explore
retinal rod cell	5 studies	38% ± 18%	Explore
brush cell	5 studies	37% ± 13%	Explore
immature B cell	5 studies	30% ± 15%	Explore
innate lymphoid cell	5 studies	29% ± 3%	Explore
hematopoietic stem cell	5 studies	25% ± 7%	Explore
deuterosomal cell	4 studies	27% ± 5%	Explore
pancreatic A cell	4 studies	79% ± 10%	Explore
type B pancreatic cell	4 studies	68% ± 13%	Explore
exhausted T cell	4 studies	53% ± 6%	Explore
glomerular endothelial cell	4 studies	37% ± 11%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	52% ± 3%	Explore
retinal cone cell	4 studies	59% ± 25%	Explore
erythroblast	4 studies	37% ± 16%	Explore
precursor B cell	4 studies	29% ± 9%	Explore
pro-B cell	4 studies	27% ± 6%	Explore
amacrine cell	4 studies	52% ± 19%	Explore
retina horizontal cell	4 studies	46% ± 21%	Explore
adventitial cell	4 studies	27% ± 9%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	38% ± 2%	Explore
GABAergic neuron	4 studies	30% ± 12%	Explore
oligodendrocyte precursor cell	4 studies	38% ± 8%	Explore
T-helper 17 cell	4 studies	33% ± 15%	Explore
duct epithelial cell	3 studies	18% ± 3%	Explore
respiratory goblet cell	3 studies	37% ± 25%	Explore
squamous epithelial cell	3 studies	44% ± 23%	Explore
pancreatic D cell	3 studies	75% ± 15%	Explore
podocyte	3 studies	65% ± 2%	Explore
intestinal crypt stem cell	3 studies	23% ± 8%	Explore
neural crest cell	3 studies	29% ± 6%	Explore
retinal bipolar neuron	3 studies	53% ± 23%	Explore
OFF-bipolar cell	3 studies	57% ± 31%	Explore
ON-bipolar cell	3 studies	56% ± 32%	Explore
GABAergic amacrine cell	3 studies	25% ± 10%	Explore
lymphocyte	3 studies	43% ± 15%	Explore
megakaryocyte	3 studies	35% ± 13%	Explore
neuroendocrine cell	3 studies	60% ± 22%	Explore
mucus secreting cell	3 studies	24% ± 5%	Explore
serous secreting cell	3 studies	19% ± 2%	Explore
intraepithelial lymphocyte	3 studies	36% ± 12%	Explore
Mueller cell	3 studies	55% ± 13%	Explore
rod bipolar cell	3 studies	43% ± 18%	Explore
muscle cell	3 studies	34% ± 24%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	49% ± 8%	Explore
intermediate monocyte	3 studies	48% ± 19%	Explore
myoepithelial cell	3 studies	31% ± 7%	Explore
luminal cell of prostate epithelium	3 studies	34% ± 8%	Explore
pancreatic ductal cell	3 studies	67% ± 7%	Explore
granulocyte	3 studies	36% ± 15%	Explore
glial cell	3 studies	45% ± 19%	Explore
hepatocyte	3 studies	43% ± 32%	Explore
group 3 innate lymphoid cell	3 studies	31% ± 16%	Explore
keratinocyte	3 studies	24% ± 4%	Explore
interneuron	3 studies	43% ± 28%	Explore
T-helper 1 cell	3 studies	34% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	26% ± 4%	Explore
progenitor cell of mammary luminal epithelium	3 studies	25% ± 5%	Explore
transit amplifying cell	3 studies	17% ± 2%	Explore
erythrocyte	3 studies	36% ± 21%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	17 studies	39% ± 13%	Explore
peripheral blood	15 studies	32% ± 11%	Explore
intestine	11 studies	30% ± 14%	Explore
brain	10 studies	31% ± 11%	Explore
kidney	9 studies	38% ± 9%	Explore
eye	8 studies	39% ± 18%	Explore
liver	6 studies	30% ± 16%	Explore
bone marrow	5 studies	23% ± 7%	Explore
lymph node	5 studies	41% ± 17%	Explore
pancreas	4 studies	65% ± 19%	Explore
uterus	4 studies	51% ± 16%	Explore
breast	4 studies	32% ± 4%	Explore
placenta	3 studies	38% ± 17%	Explore
adrenal gland	3 studies	33% ± 10%	Explore
prostate	3 studies	27% ± 6%	Explore
thymus	3 studies	40% ± 16%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4828.44	1445 / 1445	100%	18.64	183 / 183
ovary	100%	3646.15	180 / 180	100%	24.49	430 / 430
uterus	100%	4573.36	170 / 170	100%	16.87	459 / 459
brain	100%	7707.15	2641 / 2642	100%	13.35	704 / 705
intestine	100%	4715.07	966 / 966	100%	20.11	525 / 527
prostate	100%	4719.96	245 / 245	100%	16.72	500 / 502
bladder	100%	4788.76	21 / 21	99%	19.30	501 / 504
stomach	100%	3353.55	359 / 359	99%	21.54	284 / 286
skin	100%	4979.73	1808 / 1809	99%	13.35	467 / 472
kidney	100%	5811.04	89 / 89	99%	14.65	889 / 901
breast	100%	4176.32	459 / 459	98%	13.44	1101 / 1118
thymus	100%	4303.23	652 / 653	98%	13.85	595 / 605
lung	100%	4372.86	576 / 578	97%	11.13	1116 / 1155
adrenal gland	100%	4989.00	258 / 258	96%	18.82	220 / 230
pancreas	92%	1466.19	302 / 328	98%	15.15	175 / 178
liver	95%	1534.65	215 / 226	87%	10.57	354 / 406
adipose	100%	4166.61	1204 / 1204	0%	0	0 / 0
blood vessel	100%	6329.00	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	21.01	80 / 80
lymph node	0%	0	0 / 0	100%	18.69	29 / 29
spleen	100%	3501.46	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	12.76	45 / 45
ureter	0%	0	0 / 0	100%	32.45	1 / 1
muscle	99%	3256.18	796 / 803	0%	0	0 / 0
heart	98%	3981.21	848 / 861	0%	0	0 / 0
peripheral blood	98%	3396.78	911 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	DYNLRB1
Protein name	Dynein light chain roadblock-type 1 (Bithoraxoid-like protein) (BLP) (Dynein light chain 2A, cytoplasmic) (Dynein-associated protein Km23) (Roadblock domain-containing protein 1) Dynein light chain roadblock-type 1
Synonyms	BITH DNLC2A HSPC162 DNCL2A ROBLD1
Description	FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. . FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. .
Accessions	ENST00000374846.3 B1AKR6 ENST00000480759.1 [Q9NP97-2] ENST00000300469.13 [Q9NP97-2] A0A8V8TKK9 ENST00000357156.7 [Q9NP97-1] Q9NP97 ENST00000696986.1

GO_0007632	Biological process	visual behavior
GO_0007018	Biological process	microtubule-based movement
GO_0097542	Cellular component	ciliary tip
GO_0005874	Cellular component	microtubule
GO_0005813	Cellular component	centrosome
GO_0005929	Cellular component	cilium
GO_0005868	Cellular component	cytoplasmic dynein complex
GO_0030286	Cellular component	dynein complex
GO_0016020	Cellular component	membrane
GO_0005737	Cellular component	cytoplasm
GO_0045505	Molecular function	dynein intermediate chain binding
GO_0005515	Molecular function	protein binding
GO_0003777	Molecular function	microtubule motor activity

DYNLRB1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review