DDX18 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	37 studies	30% ± 11%	Explore
fibroblast	35 studies	25% ± 9%	Explore
natural killer cell	33 studies	28% ± 6%	Explore
CD8-positive, alpha-beta T cell	31 studies	28% ± 8%	Explore
B cell	30 studies	29% ± 5%	Explore
CD4-positive, alpha-beta T cell	30 studies	30% ± 10%	Explore
pericyte	29 studies	28% ± 7%	Explore
T cell	27 studies	26% ± 8%	Explore
macrophage	25 studies	25% ± 8%	Explore
smooth muscle cell	25 studies	25% ± 8%	Explore
regulatory T cell	22 studies	29% ± 7%	Explore
classical monocyte	20 studies	22% ± 6%	Explore
conventional dendritic cell	20 studies	24% ± 11%	Explore
naive B cell	19 studies	27% ± 5%	Explore
non-classical monocyte	18 studies	27% ± 10%	Explore
memory B cell	18 studies	27% ± 6%	Explore
plasmacytoid dendritic cell	17 studies	31% ± 12%	Explore
mature NK T cell	17 studies	27% ± 7%	Explore
gamma-delta T cell	17 studies	31% ± 12%	Explore
mast cell	16 studies	24% ± 7%	Explore
endothelial cell of lymphatic vessel	16 studies	27% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	16 studies	33% ± 9%	Explore
basal cell	15 studies	30% ± 13%	Explore
monocyte	14 studies	24% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	24% ± 5%	Explore
ciliated cell	14 studies	31% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	26% ± 6%	Explore
myofibroblast cell	14 studies	26% ± 7%	Explore
mucosal invariant T cell	13 studies	28% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	30% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	35% ± 7%	Explore
capillary endothelial cell	12 studies	28% ± 5%	Explore
vein endothelial cell	12 studies	26% ± 6%	Explore
epithelial cell	12 studies	35% ± 19%	Explore
plasma cell	11 studies	33% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	28% ± 9%	Explore
connective tissue cell	11 studies	26% ± 7%	Explore
abnormal cell	10 studies	29% ± 11%	Explore
endothelial cell of artery	10 studies	27% ± 6%	Explore
endothelial cell of vascular tree	10 studies	28% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	31% ± 7%	Explore
plasmablast	8 studies	34% ± 18%	Explore
oligodendrocyte	8 studies	24% ± 9%	Explore
astrocyte	8 studies	26% ± 9%	Explore
oligodendrocyte precursor cell	8 studies	29% ± 9%	Explore
secretory cell	7 studies	27% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	27% ± 7%	Explore
leukocyte	7 studies	29% ± 9%	Explore
neuron	7 studies	28% ± 11%	Explore
glutamatergic neuron	7 studies	31% ± 16%	Explore
myeloid cell	7 studies	27% ± 13%	Explore
T follicular helper cell	7 studies	30% ± 10%	Explore
hematopoietic precursor cell	6 studies	28% ± 12%	Explore
dendritic cell	6 studies	33% ± 20%	Explore
type II pneumocyte	6 studies	26% ± 15%	Explore
mesothelial cell	6 studies	23% ± 13%	Explore
type I pneumocyte	5 studies	29% ± 8%	Explore
club cell	5 studies	24% ± 12%	Explore
exhausted T cell	5 studies	26% ± 3%	Explore
progenitor cell	5 studies	20% ± 3%	Explore
transit amplifying cell	5 studies	27% ± 14%	Explore
erythroblast	5 studies	35% ± 14%	Explore
retinal rod cell	5 studies	26% ± 10%	Explore
microglial cell	5 studies	24% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	36% ± 10%	Explore
innate lymphoid cell	5 studies	32% ± 5%	Explore
GABAergic neuron	5 studies	30% ± 10%	Explore
interneuron	5 studies	29% ± 14%	Explore
pancreatic A cell	4 studies	27% ± 10%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	29% ± 7%	Explore
mononuclear phagocyte	4 studies	31% ± 11%	Explore
kidney loop of Henle epithelial cell	4 studies	19% ± 2%	Explore
epithelial cell of proximal tubule	4 studies	18% ± 2%	Explore
retinal bipolar neuron	4 studies	38% ± 12%	Explore
lymphocyte	4 studies	31% ± 12%	Explore
immature B cell	4 studies	27% ± 5%	Explore
precursor B cell	4 studies	36% ± 11%	Explore
pro-B cell	4 studies	26% ± 2%	Explore
amacrine cell	4 studies	37% ± 17%	Explore
alveolar macrophage	4 studies	18% ± 1%	Explore
adipocyte	4 studies	21% ± 4%	Explore
CD4-positive helper T cell	4 studies	32% ± 10%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	27% ± 8%	Explore
hematopoietic stem cell	4 studies	25% ± 6%	Explore
goblet cell	4 studies	29% ± 6%	Explore
T-helper 17 cell	4 studies	27% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	27% ± 5%	Explore
respiratory goblet cell	3 studies	29% ± 16%	Explore
type B pancreatic cell	3 studies	28% ± 8%	Explore
glomerular endothelial cell	3 studies	25% ± 3%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	27% ± 8%	Explore
neural crest cell	3 studies	26% ± 4%	Explore
IgG plasma cell	3 studies	16% ± 1%	Explore
placental villous trophoblast	3 studies	18% ± 2%	Explore
megakaryocyte	3 studies	20% ± 5%	Explore
retina horizontal cell	3 studies	37% ± 14%	Explore
retinal cone cell	3 studies	39% ± 14%	Explore
Mueller cell	3 studies	25% ± 4%	Explore
rod bipolar cell	3 studies	30% ± 12%	Explore
germinal center B cell	3 studies	28% ± 1%	Explore
intermediate monocyte	3 studies	36% ± 18%	Explore
muscle cell	3 studies	32% ± 10%	Explore
pancreatic ductal cell	3 studies	38% ± 10%	Explore
granulocyte monocyte progenitor cell	3 studies	25% ± 3%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	41% ± 17%	Explore
enteroendocrine cell	3 studies	26% ± 6%	Explore
intestinal crypt stem cell	3 studies	29% ± 7%	Explore
glial cell	3 studies	29% ± 15%	Explore
erythrocyte	3 studies	38% ± 15%	Explore
group 3 innate lymphoid cell	3 studies	37% ± 12%	Explore
T-helper 1 cell	3 studies	30% ± 11%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	35% ± 3%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	34% ± 7%	Explore
double negative thymocyte	3 studies	40% ± 15%	Explore
hepatocyte	3 studies	47% ± 17%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	29% ± 8%	Explore
lung	16 studies	28% ± 11%	Explore
brain	12 studies	28% ± 10%	Explore
kidney	8 studies	21% ± 4%	Explore
intestine	8 studies	25% ± 9%	Explore
eye	8 studies	27% ± 10%	Explore
liver	7 studies	32% ± 14%	Explore
bone marrow	5 studies	21% ± 2%	Explore
lymph node	5 studies	28% ± 7%	Explore
uterus	4 studies	35% ± 13%	Explore
breast	4 studies	25% ± 6%	Explore
pancreas	3 studies	31% ± 9%	Explore
placenta	3 studies	20% ± 4%	Explore
thymus	3 studies	34% ± 12%	Explore
adipose	3 studies	23% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3600.67	1445 / 1445	100%	47.66	183 / 183
intestine	100%	3886.41	966 / 966	100%	47.39	527 / 527
lung	100%	3506.56	578 / 578	100%	45.72	1155 / 1155
ovary	100%	3949.62	180 / 180	100%	28.49	430 / 430
breast	100%	4161.81	459 / 459	100%	43.20	1117 / 1118
stomach	100%	2893.35	359 / 359	100%	43.70	285 / 286
brain	100%	2120.66	2632 / 2642	100%	35.18	705 / 705
bladder	100%	3957.52	21 / 21	100%	36.85	502 / 504
prostate	100%	2971.69	245 / 245	100%	27.29	500 / 502
uterus	100%	4124.91	170 / 170	99%	37.59	456 / 459
thymus	100%	3721.21	653 / 653	99%	31.40	599 / 605
pancreas	100%	2257.47	328 / 328	99%	29.71	176 / 178
kidney	100%	2426.67	89 / 89	98%	30.88	885 / 901
skin	100%	4476.20	1809 / 1809	98%	39.24	461 / 472
liver	100%	2015.07	226 / 226	96%	19.36	388 / 406
adrenal gland	100%	2754.69	258 / 258	93%	16.68	214 / 230
adipose	100%	4250.41	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4203.76	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	37.86	29 / 29
spleen	100%	3786.01	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	36.79	45 / 45
ureter	0%	0	0 / 0	100%	11.00	1 / 1
muscle	100%	2022.93	800 / 803	0%	0	0 / 0
heart	97%	1972.60	839 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	91%	17.33	73 / 80
peripheral blood	83%	3057.81	770 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0000463	Biological process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0005730	Cellular component	nucleolus
GO_0005694	Cellular component	chromosome
GO_0016020	Cellular component	membrane
GO_0005515	Molecular function	protein binding
GO_0003724	Molecular function	RNA helicase activity
GO_0016887	Molecular function	ATP hydrolysis activity
GO_0005524	Molecular function	ATP binding
GO_0003723	Molecular function	RNA binding

Gene name	DDX18
Protein name	ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb) ATP-dependent RNA helicase (EC 3.6.4.13) Uncharacterized protein DDX18
Synonyms	cPERP-D
Description	FUNCTION: Probable RNA-dependent helicase. FUNCTION: RNA helicase. . FUNCTION: RNA helicase. .
Accessions	H7C452 Q4ZG72 Q9NVP1 ENST00000263239.7 Q53TI6 ENST00000415038.1

DDX18 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review