COX17 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	34 studies	30% ± 10%	Explore
natural killer cell	33 studies	27% ± 7%	Explore
endothelial cell	30 studies	36% ± 14%	Explore
macrophage	28 studies	34% ± 13%	Explore
CD8-positive, alpha-beta T cell	28 studies	27% ± 12%	Explore
T cell	27 studies	25% ± 8%	Explore
CD4-positive, alpha-beta T cell	24 studies	27% ± 12%	Explore
pericyte	24 studies	30% ± 15%	Explore
conventional dendritic cell	23 studies	35% ± 11%	Explore
non-classical monocyte	23 studies	37% ± 13%	Explore
classical monocyte	22 studies	31% ± 9%	Explore
mast cell	21 studies	40% ± 13%	Explore
smooth muscle cell	21 studies	29% ± 11%	Explore
fibroblast	19 studies	25% ± 11%	Explore
regulatory T cell	19 studies	32% ± 7%	Explore
dendritic cell	18 studies	37% ± 19%	Explore
plasmacytoid dendritic cell	18 studies	32% ± 12%	Explore
memory B cell	17 studies	30% ± 8%	Explore
epithelial cell	17 studies	41% ± 21%	Explore
naive B cell	17 studies	24% ± 7%	Explore
plasma cell	16 studies	41% ± 13%	Explore
monocyte	16 studies	36% ± 10%	Explore
endothelial cell of lymphatic vessel	15 studies	39% ± 10%	Explore
ciliated cell	15 studies	59% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	26% ± 6%	Explore
mature NK T cell	14 studies	24% ± 4%	Explore
gamma-delta T cell	14 studies	29% ± 13%	Explore
basal cell	13 studies	33% ± 16%	Explore
capillary endothelial cell	12 studies	32% ± 6%	Explore
endothelial cell of vascular tree	12 studies	36% ± 12%	Explore
myeloid cell	12 studies	34% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	25% ± 5%	Explore
goblet cell	11 studies	35% ± 16%	Explore
plasmablast	10 studies	41% ± 21%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	27% ± 6%	Explore
endothelial cell of artery	10 studies	39% ± 8%	Explore
vein endothelial cell	10 studies	24% ± 5%	Explore
mucosal invariant T cell	10 studies	23% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	24% ± 8%	Explore
secretory cell	9 studies	37% ± 16%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	24% ± 6%	Explore
type I pneumocyte	8 studies	36% ± 13%	Explore
leukocyte	8 studies	29% ± 11%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	22% ± 3%	Explore
enterocyte	8 studies	32% ± 14%	Explore
abnormal cell	8 studies	34% ± 10%	Explore
type II pneumocyte	7 studies	44% ± 23%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	26% ± 5%	Explore
epithelial cell of proximal tubule	7 studies	35% ± 10%	Explore
connective tissue cell	7 studies	22% ± 4%	Explore
progenitor cell	7 studies	26% ± 15%	Explore
T follicular helper cell	7 studies	24% ± 3%	Explore
club cell	6 studies	36% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	35% ± 8%	Explore
kidney loop of Henle epithelial cell	6 studies	40% ± 5%	Explore
renal alpha-intercalated cell	6 studies	58% ± 18%	Explore
retinal rod cell	6 studies	47% ± 24%	Explore
retinal cone cell	6 studies	60% ± 32%	Explore
innate lymphoid cell	6 studies	26% ± 2%	Explore
neuron	6 studies	36% ± 19%	Explore
alveolar macrophage	5 studies	44% ± 14%	Explore
ionocyte	5 studies	41% ± 10%	Explore
respiratory goblet cell	5 studies	37% ± 13%	Explore
mononuclear phagocyte	5 studies	36% ± 12%	Explore
myofibroblast cell	5 studies	25% ± 7%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	39% ± 12%	Explore
enteroendocrine cell	5 studies	46% ± 21%	Explore
retinal ganglion cell	5 studies	63% ± 29%	Explore
brush cell	5 studies	34% ± 11%	Explore
neuroendocrine cell	5 studies	67% ± 21%	Explore
cardiac muscle cell	5 studies	21% ± 6%	Explore
erythrocyte	5 studies	30% ± 20%	Explore
intermediate monocyte	5 studies	49% ± 14%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	28% ± 9%	Explore
platelet	4 studies	22% ± 3%	Explore
pancreatic A cell	4 studies	84% ± 12%	Explore
type B pancreatic cell	4 studies	81% ± 11%	Explore
exhausted T cell	4 studies	35% ± 4%	Explore
hematopoietic precursor cell	4 studies	36% ± 11%	Explore
glomerular endothelial cell	4 studies	44% ± 9%	Explore
transit amplifying cell	4 studies	27% ± 6%	Explore
OFF-bipolar cell	4 studies	50% ± 30%	Explore
ON-bipolar cell	4 studies	50% ± 30%	Explore
erythroblast	4 studies	39% ± 26%	Explore
precursor B cell	4 studies	30% ± 9%	Explore
amacrine cell	4 studies	47% ± 18%	Explore
astrocyte	4 studies	31% ± 13%	Explore
retina horizontal cell	4 studies	45% ± 19%	Explore
microglial cell	4 studies	31% ± 15%	Explore
germinal center B cell	4 studies	37% ± 14%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	31% ± 8%	Explore
CD4-positive helper T cell	4 studies	21% ± 7%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	35% ± 9%	Explore
T-helper 17 cell	4 studies	33% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	23% ± 4%	Explore
deuterosomal cell	3 studies	55% ± 5%	Explore
duct epithelial cell	3 studies	32% ± 9%	Explore
pancreatic D cell	3 studies	81% ± 17%	Explore
podocyte	3 studies	40% ± 3%	Explore
IgG plasma cell	3 studies	24% ± 2%	Explore
retinal bipolar neuron	3 studies	61% ± 28%	Explore
renal principal cell	3 studies	52% ± 0%	Explore
extravillous trophoblast	3 studies	26% ± 4%	Explore
placental villous trophoblast	3 studies	21% ± 6%	Explore
lymphocyte	3 studies	42% ± 4%	Explore
megakaryocyte	3 studies	32% ± 5%	Explore
immature B cell	3 studies	22% ± 4%	Explore
retinal pigment epithelial cell	3 studies	48% ± 28%	Explore
mucus secreting cell	3 studies	47% ± 17%	Explore
serous secreting cell	3 studies	44% ± 20%	Explore
intraepithelial lymphocyte	3 studies	28% ± 9%	Explore
Mueller cell	3 studies	40% ± 10%	Explore
rod bipolar cell	3 studies	53% ± 22%	Explore
oligodendrocyte	3 studies	21% ± 3%	Explore
inflammatory macrophage	3 studies	24% ± 6%	Explore
granulocyte	3 studies	41% ± 11%	Explore
luminal cell of prostate epithelium	3 studies	46% ± 9%	Explore
pancreatic ductal cell	3 studies	59% ± 9%	Explore
neutrophil	3 studies	25% ± 6%	Explore
glial cell	3 studies	22% ± 8%	Explore
hepatocyte	3 studies	62% ± 32%	Explore
group 3 innate lymphoid cell	3 studies	30% ± 11%	Explore
T-helper 1 cell	3 studies	32% ± 9%	Explore
double negative thymocyte	3 studies	36% ± 16%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	17 studies	37% ± 13%	Explore
peripheral blood	16 studies	27% ± 8%	Explore
intestine	11 studies	24% ± 8%	Explore
kidney	9 studies	31% ± 9%	Explore
eye	9 studies	37% ± 22%	Explore
brain	6 studies	24% ± 6%	Explore
liver	6 studies	37% ± 22%	Explore
lymph node	5 studies	32% ± 8%	Explore
pancreas	4 studies	70% ± 20%	Explore
bone marrow	4 studies	22% ± 3%	Explore
uterus	4 studies	35% ± 15%	Explore
prostate	4 studies	26% ± 6%	Explore
breast	4 studies	25% ± 2%	Explore
placenta	3 studies	26% ± 4%	Explore
heart	3 studies	19% ± 3%	Explore
adrenal gland	3 studies	35% ± 4%	Explore
thymus	3 studies	36% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	2951.63	258 / 258	100%	113.64	230 / 230
esophagus	100%	1280.21	1445 / 1445	100%	43.04	183 / 183
kidney	100%	1781.17	89 / 89	100%	44.69	901 / 901
uterus	100%	1033.45	170 / 170	100%	64.27	459 / 459
intestine	100%	1325.97	966 / 966	100%	44.67	526 / 527
bladder	100%	1122.48	21 / 21	100%	53.16	503 / 504
thymus	100%	1413.84	652 / 653	100%	55.29	604 / 605
stomach	100%	1302.25	359 / 359	100%	43.78	285 / 286
liver	100%	1436.69	225 / 226	100%	59.61	406 / 406
lung	99%	1348.52	575 / 578	100%	48.80	1155 / 1155
ovary	99%	655.38	179 / 180	100%	47.24	430 / 430
brain	99%	1269.97	2627 / 2642	100%	34.62	705 / 705
prostate	100%	1340.60	244 / 245	100%	69.83	501 / 502
pancreas	99%	756.74	326 / 328	100%	57.18	178 / 178
breast	100%	1163.29	459 / 459	99%	57.15	1107 / 1118
skin	98%	662.30	1767 / 1809	100%	47.80	471 / 472
eye	0%	0	0 / 0	100%	33.45	80 / 80
lymph node	0%	0	0 / 0	100%	97.88	29 / 29
muscle	100%	3352.22	803 / 803	0%	0	0 / 0
spleen	100%	1239.23	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	58.19	45 / 45
ureter	0%	0	0 / 0	100%	45.78	1 / 1
adipose	100%	1204.64	1202 / 1204	0%	0	0 / 0
heart	100%	2836.49	857 / 861	0%	0	0 / 0
blood vessel	99%	1249.43	1328 / 1335	0%	0	0 / 0
peripheral blood	69%	1123.45	637 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0006091	Biological process	generation of precursor metabolites and energy
GO_0033617	Biological process	mitochondrial cytochrome c oxidase assembly
GO_0006825	Biological process	copper ion transport
GO_1904960	Biological process	positive regulation of cytochrome-c oxidase activity
GO_0005758	Cellular component	mitochondrial intermembrane space
GO_0005737	Cellular component	cytoplasm
GO_0008047	Molecular function	enzyme activator activity
GO_1903136	Molecular function	cuprous ion binding
GO_0005507	Molecular function	copper ion binding
GO_0005515	Molecular function	protein binding
GO_0016531	Molecular function	copper chaperone activity

IV. Literature review

[source]

Gene name	COX17
Protein name	Cytochrome c oxidase copper chaperone COX17 Cytochrome c oxidase copper chaperone COX17 (HCG2022684, isoform CRA_b) Cytochrome c oxidase copper chaperone
Synonyms	hCG_2022684
Description	FUNCTION: Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2). .
Accessions	C9J8T6 ENST00000497116.1 Q14061 ENST00000261070.7 H7C4E5 H7C5P5 ENST00000490145.1 ENST00000484810.5 ENST00000486606.5 ENST00000468918.5

COX17 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review