CCT2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	30 studies	27% ± 7%	Explore
endothelial cell	27 studies	30% ± 11%	Explore
natural killer cell	26 studies	29% ± 11%	Explore
fibroblast	24 studies	31% ± 10%	Explore
CD4-positive, alpha-beta T cell	24 studies	29% ± 16%	Explore
T cell	22 studies	28% ± 11%	Explore
CD8-positive, alpha-beta T cell	22 studies	33% ± 14%	Explore
conventional dendritic cell	21 studies	29% ± 13%	Explore
smooth muscle cell	19 studies	31% ± 10%	Explore
pericyte	19 studies	30% ± 11%	Explore
regulatory T cell	19 studies	26% ± 12%	Explore
memory B cell	17 studies	27% ± 11%	Explore
basal cell	17 studies	33% ± 14%	Explore
naive B cell	17 studies	26% ± 7%	Explore
ciliated cell	16 studies	39% ± 16%	Explore
plasmacytoid dendritic cell	15 studies	28% ± 10%	Explore
epithelial cell	15 studies	38% ± 21%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	25% ± 7%	Explore
macrophage	14 studies	22% ± 8%	Explore
gamma-delta T cell	14 studies	30% ± 16%	Explore
mature NK T cell	13 studies	24% ± 8%	Explore
connective tissue cell	13 studies	36% ± 14%	Explore
endothelial cell of lymphatic vessel	12 studies	30% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	25% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	28% ± 8%	Explore
mast cell	11 studies	28% ± 15%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	29% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	29% ± 8%	Explore
abnormal cell	10 studies	36% ± 14%	Explore
endothelial cell of vascular tree	10 studies	30% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	27% ± 7%	Explore
myofibroblast cell	9 studies	38% ± 13%	Explore
mucosal invariant T cell	9 studies	28% ± 5%	Explore
plasmablast	8 studies	51% ± 22%	Explore
secretory cell	8 studies	28% ± 15%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	33% ± 16%	Explore
neuron	8 studies	45% ± 22%	Explore
vein endothelial cell	8 studies	26% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	27% ± 5%	Explore
progenitor cell	7 studies	47% ± 10%	Explore
endothelial cell of artery	7 studies	21% ± 4%	Explore
precursor B cell	7 studies	42% ± 11%	Explore
innate lymphoid cell	7 studies	25% ± 4%	Explore
non-classical monocyte	6 studies	25% ± 5%	Explore
epithelial cell of proximal tubule	6 studies	24% ± 12%	Explore
goblet cell	6 studies	23% ± 8%	Explore
mesothelial cell	6 studies	43% ± 14%	Explore
transit amplifying cell	6 studies	27% ± 6%	Explore
dendritic cell	6 studies	39% ± 19%	Explore
hematopoietic stem cell	6 studies	53% ± 9%	Explore
myeloid cell	6 studies	26% ± 13%	Explore
erythrocyte	6 studies	43% ± 26%	Explore
T follicular helper cell	6 studies	21% ± 4%	Explore
GABAergic neuron	6 studies	30% ± 12%	Explore
oligodendrocyte precursor cell	6 studies	34% ± 11%	Explore
type I pneumocyte	5 studies	27% ± 9%	Explore
hematopoietic precursor cell	5 studies	56% ± 22%	Explore
plasma cell	5 studies	45% ± 19%	Explore
classical monocyte	5 studies	23% ± 8%	Explore
enteroendocrine cell	5 studies	34% ± 11%	Explore
erythroblast	5 studies	56% ± 25%	Explore
pro-B cell	5 studies	44% ± 11%	Explore
capillary endothelial cell	5 studies	31% ± 13%	Explore
immature B cell	5 studies	39% ± 14%	Explore
astrocyte	5 studies	22% ± 7%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	32% ± 10%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	30% ± 6%	Explore
glutamatergic neuron	5 studies	40% ± 11%	Explore
interneuron	5 studies	29% ± 9%	Explore
deuterosomal cell	4 studies	32% ± 4%	Explore
leukocyte	4 studies	29% ± 7%	Explore
exhausted T cell	4 studies	29% ± 7%	Explore
kidney loop of Henle epithelial cell	4 studies	21% ± 5%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	47% ± 21%	Explore
intestinal crypt stem cell	4 studies	33% ± 5%	Explore
retinal ganglion cell	4 studies	46% ± 27%	Explore
club cell	4 studies	27% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	29% ± 10%	Explore
granulocyte	4 studies	24% ± 9%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	64% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	20% ± 5%	Explore
precursor cell	3 studies	64% ± 16%	Explore
respiratory goblet cell	3 studies	31% ± 21%	Explore
pancreatic A cell	3 studies	53% ± 10%	Explore
type B pancreatic cell	3 studies	44% ± 19%	Explore
mononuclear phagocyte	3 studies	29% ± 13%	Explore
renal alpha-intercalated cell	3 studies	32% ± 14%	Explore
neural crest cell	3 studies	52% ± 6%	Explore
extravillous trophoblast	3 studies	22% ± 2%	Explore
placental villous trophoblast	3 studies	35% ± 8%	Explore
common myeloid progenitor	3 studies	42% ± 22%	Explore
lymphocyte	3 studies	39% ± 7%	Explore
brush cell	3 studies	37% ± 18%	Explore
neuroendocrine cell	3 studies	37% ± 13%	Explore
type II pneumocyte	3 studies	32% ± 9%	Explore
retinal cone cell	3 studies	30% ± 14%	Explore
monocyte	3 studies	25% ± 3%	Explore
acinar cell	3 studies	46% ± 23%	Explore
muscle cell	3 studies	29% ± 13%	Explore
germinal center B cell	3 studies	33% ± 8%	Explore
pancreatic ductal cell	3 studies	57% ± 21%	Explore
granulocyte monocyte progenitor cell	3 studies	42% ± 27%	Explore
group 3 innate lymphoid cell	3 studies	42% ± 15%	Explore
keratinocyte	3 studies	19% ± 1%	Explore
oligodendrocyte	3 studies	22% ± 3%	Explore
T-helper 1 cell	3 studies	33% ± 11%	Explore
double negative thymocyte	3 studies	47% ± 23%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	24% ± 9%	Explore
progenitor cell of mammary luminal epithelium	3 studies	29% ± 8%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	27% ± 10%	Explore
lung	12 studies	32% ± 14%	Explore
brain	9 studies	27% ± 9%	Explore
kidney	8 studies	24% ± 9%	Explore
intestine	7 studies	29% ± 12%	Explore
liver	6 studies	32% ± 23%	Explore
bone marrow	5 studies	25% ± 6%	Explore
eye	5 studies	25% ± 9%	Explore
uterus	5 studies	29% ± 15%	Explore
lymph node	5 studies	33% ± 17%	Explore
breast	4 studies	26% ± 7%	Explore
pancreas	3 studies	51% ± 14%	Explore
placenta	3 studies	28% ± 6%	Explore
prostate	3 studies	26% ± 6%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	5168.83	180 / 180	100%	122.77	430 / 430
stomach	100%	4282.74	359 / 359	100%	153.52	286 / 286
lung	100%	4966.64	577 / 578	100%	142.53	1155 / 1155
breast	100%	5444.39	459 / 459	100%	171.27	1116 / 1118
intestine	100%	5352.95	966 / 966	100%	175.29	526 / 527
bladder	100%	5832.29	21 / 21	100%	203.91	502 / 504
uterus	100%	5090.08	170 / 170	100%	149.37	457 / 459
esophagus	100%	5345.42	1445 / 1445	99%	131.09	182 / 183
brain	99%	4664.65	2627 / 2642	100%	154.86	704 / 705
prostate	100%	4243.30	245 / 245	99%	116.46	497 / 502
thymus	100%	4172.26	652 / 653	99%	83.06	599 / 605
skin	100%	6995.74	1809 / 1809	99%	157.03	465 / 472
pancreas	99%	3090.97	324 / 328	99%	90.67	177 / 178
kidney	100%	4670.02	89 / 89	98%	88.95	882 / 901
adrenal gland	100%	6139.23	258 / 258	95%	85.49	219 / 230
liver	97%	2640.83	219 / 226	97%	68.04	392 / 406
adipose	100%	5626.15	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	167.25	29 / 29
muscle	100%	5871.73	803 / 803	0%	0	0 / 0
spleen	100%	4759.07	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	168.46	45 / 45
ureter	0%	0	0 / 0	100%	55.69	1 / 1
blood vessel	100%	4957.31	1333 / 1335	0%	0	0 / 0
heart	95%	4481.35	817 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	94%	85.41	75 / 80
peripheral blood	67%	4182.04	622 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0