BBX | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	38 studies	30% ± 14%	Explore
fibroblast	37 studies	27% ± 13%	Explore
B cell	35 studies	30% ± 9%	Explore
pericyte	34 studies	32% ± 12%	Explore
natural killer cell	30 studies	23% ± 6%	Explore
smooth muscle cell	29 studies	28% ± 7%	Explore
CD4-positive, alpha-beta T cell	24 studies	23% ± 6%	Explore
CD8-positive, alpha-beta T cell	24 studies	23% ± 6%	Explore
T cell	20 studies	25% ± 7%	Explore
astrocyte	20 studies	40% ± 17%	Explore
macrophage	20 studies	29% ± 14%	Explore
naive B cell	19 studies	27% ± 5%	Explore
memory B cell	17 studies	28% ± 5%	Explore
regulatory T cell	17 studies	22% ± 5%	Explore
basal cell	16 studies	31% ± 16%	Explore
oligodendrocyte	16 studies	51% ± 17%	Explore
oligodendrocyte precursor cell	16 studies	38% ± 18%	Explore
gamma-delta T cell	16 studies	23% ± 6%	Explore
endothelial cell of lymphatic vessel	14 studies	26% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	23% ± 5%	Explore
microglial cell	14 studies	41% ± 15%	Explore
ciliated cell	13 studies	28% ± 13%	Explore
mature NK T cell	13 studies	22% ± 5%	Explore
mucosal invariant T cell	13 studies	22% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	23% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	23% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	23% ± 4%	Explore
plasmacytoid dendritic cell	12 studies	24% ± 8%	Explore
connective tissue cell	11 studies	27% ± 8%	Explore
epithelial cell	11 studies	41% ± 21%	Explore
type I pneumocyte	10 studies	28% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	28% ± 7%	Explore
myofibroblast cell	10 studies	27% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	25% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	21% ± 5%	Explore
non-classical monocyte	9 studies	22% ± 7%	Explore
GABAergic neuron	9 studies	38% ± 21%	Explore
glutamatergic neuron	9 studies	41% ± 25%	Explore
conventional dendritic cell	9 studies	26% ± 10%	Explore
capillary endothelial cell	9 studies	20% ± 5%	Explore
endothelial cell of artery	9 studies	21% ± 2%	Explore
mast cell	9 studies	24% ± 7%	Explore
neuron	8 studies	37% ± 23%	Explore
endothelial cell of vascular tree	8 studies	27% ± 14%	Explore
secretory cell	7 studies	24% ± 8%	Explore
leukocyte	7 studies	34% ± 16%	Explore
abnormal cell	7 studies	27% ± 10%	Explore
mesothelial cell	7 studies	27% ± 11%	Explore
myeloid cell	7 studies	25% ± 8%	Explore
club cell	7 studies	33% ± 9%	Explore
amacrine cell	7 studies	39% ± 15%	Explore
retinal rod cell	7 studies	27% ± 7%	Explore
monocyte	7 studies	29% ± 7%	Explore
adipocyte	7 studies	25% ± 6%	Explore
vein endothelial cell	7 studies	26% ± 16%	Explore
respiratory goblet cell	6 studies	31% ± 13%	Explore
glial cell	6 studies	31% ± 12%	Explore
interneuron	6 studies	40% ± 19%	Explore
precursor B cell	6 studies	34% ± 9%	Explore
retina horizontal cell	6 studies	50% ± 11%	Explore
dendritic cell	6 studies	38% ± 12%	Explore
Mueller cell	6 studies	47% ± 11%	Explore
type II pneumocyte	6 studies	30% ± 5%	Explore
goblet cell	6 studies	31% ± 22%	Explore
ionocyte	5 studies	34% ± 10%	Explore
progenitor cell	5 studies	31% ± 6%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	25% ± 4%	Explore
retinal bipolar neuron	5 studies	30% ± 9%	Explore
retinal ganglion cell	5 studies	38% ± 15%	Explore
kidney loop of Henle epithelial cell	5 studies	23% ± 5%	Explore
pro-B cell	5 studies	31% ± 6%	Explore
brush cell	5 studies	37% ± 14%	Explore
retinal cone cell	5 studies	29% ± 11%	Explore
cardiac muscle cell	5 studies	26% ± 5%	Explore
lymphocyte	5 studies	39% ± 17%	Explore
T follicular helper cell	5 studies	24% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	24% ± 10%	Explore
innate lymphoid cell	5 studies	22% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	22% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	20% ± 4%	Explore
mononuclear phagocyte	4 studies	22% ± 6%	Explore
hematopoietic precursor cell	4 studies	30% ± 10%	Explore
epithelial cell of proximal tubule	4 studies	20% ± 5%	Explore
renal alpha-intercalated cell	4 studies	28% ± 7%	Explore
granule cell	4 studies	25% ± 2%	Explore
plasma cell	4 studies	30% ± 5%	Explore
immature B cell	4 studies	32% ± 9%	Explore
retinal pigment epithelial cell	4 studies	34% ± 17%	Explore
hepatocyte	4 studies	36% ± 14%	Explore
hematopoietic stem cell	4 studies	23% ± 7%	Explore
enteroendocrine cell	4 studies	28% ± 10%	Explore
alveolar macrophage	4 studies	31% ± 11%	Explore
renal principal cell	4 studies	25% ± 4%	Explore
pancreatic A cell	3 studies	42% ± 12%	Explore
type B pancreatic cell	3 studies	52% ± 18%	Explore
exhausted T cell	3 studies	25% ± 8%	Explore
glomerular endothelial cell	3 studies	19% ± 2%	Explore
podocyte	3 studies	40% ± 7%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	38% ± 13%	Explore
neural crest cell	3 studies	23% ± 2%	Explore
placental villous trophoblast	3 studies	54% ± 3%	Explore
GABAergic amacrine cell	3 studies	33% ± 10%	Explore
OFF-bipolar cell	3 studies	29% ± 8%	Explore
ON-bipolar cell	3 studies	33% ± 8%	Explore
glycinergic amacrine cell	3 studies	30% ± 5%	Explore
rod bipolar cell	3 studies	42% ± 5%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	22% ± 3%	Explore
muscle cell	3 studies	46% ± 25%	Explore
neural progenitor cell	3 studies	40% ± 13%	Explore
ependymal cell	3 studies	45% ± 19%	Explore
granulocyte	3 studies	21% ± 7%	Explore
intestinal crypt stem cell	3 studies	19% ± 4%	Explore
adventitial cell	3 studies	25% ± 4%	Explore
chondrocyte	3 studies	30% ± 7%	Explore
group 3 innate lymphoid cell	3 studies	27% ± 8%	Explore
transit amplifying cell	3 studies	40% ± 33%	Explore
T-helper 17 cell	3 studies	19% ± 3%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	20% ± 3%	Explore
double negative thymocyte	3 studies	31% ± 8%	Explore
myoepithelial cell	3 studies	29% ± 6%	Explore
mural cell	3 studies	45% ± 14%	Explore
mucus secreting cell	3 studies	32% ± 11%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	19 studies	36% ± 21%	Explore
lung	15 studies	27% ± 9%	Explore
peripheral blood	14 studies	23% ± 9%	Explore
eye	10 studies	34% ± 13%	Explore
kidney	9 studies	23% ± 6%	Explore
intestine	6 studies	19% ± 7%	Explore
heart	5 studies	24% ± 5%	Explore
lymph node	5 studies	21% ± 4%	Explore
liver	5 studies	26% ± 11%	Explore
bone marrow	4 studies	23% ± 8%	Explore
breast	4 studies	17% ± 2%	Explore
adipose	4 studies	28% ± 5%	Explore
pancreas	3 studies	45% ± 13%	Explore
placenta	3 studies	35% ± 3%	Explore
uterus	3 studies	29% ± 12%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	2995.95	2636 / 2642	100%	28.87	703 / 705
lung	100%	3535.12	577 / 578	100%	19.47	1150 / 1155
esophagus	100%	3405.35	1443 / 1445	99%	23.63	182 / 183
ovary	100%	5159.98	180 / 180	99%	17.76	427 / 430
breast	100%	3466.93	459 / 459	99%	26.66	1109 / 1118
adrenal gland	100%	6699.50	258 / 258	99%	24.90	228 / 230
prostate	100%	4667.09	245 / 245	99%	23.74	497 / 502
thymus	100%	4431.29	653 / 653	99%	25.31	598 / 605
kidney	100%	2987.84	89 / 89	98%	22.02	881 / 901
uterus	100%	4335.12	170 / 170	97%	17.69	446 / 459
pancreas	96%	1514.13	316 / 328	99%	18.64	176 / 178
stomach	100%	2417.50	359 / 359	95%	14.99	272 / 286
bladder	100%	4340.95	21 / 21	94%	15.35	475 / 504
intestine	100%	3814.11	965 / 966	94%	12.50	496 / 527
skin	100%	3573.56	1803 / 1809	92%	20.04	432 / 472
liver	81%	883.04	183 / 226	62%	5.91	253 / 406
adipose	100%	3367.97	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5573.37	1335 / 1335	0%	0	0 / 0
spleen	100%	3094.76	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	6.56	1 / 1
muscle	98%	1455.95	784 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	12.36	28 / 29
tonsil	0%	0	0 / 0	96%	20.32	43 / 45
heart	93%	2277.95	804 / 861	0%	0	0 / 0
peripheral blood	74%	1821.75	690 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	66%	7.22	53 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	BBX
Protein name	HMG box transcription factor BBX (Bobby sox homolog) (HMG box-containing protein 2) BBX high mobility group box domain containing
Synonyms	HBP2
Description	FUNCTION: Transcription factor that is necessary for cell cycle progression from G1 to S phase. .
Accessions	C9J8D0 C9JC04 ENST00000449213.5 C9JD74 Q8WY36 ENST00000457496.5 ENST00000325805.13 [Q8WY36-1] H7C1Q0 C9IYS9 C9JYU6 ENST00000458347.1 ENST00000406780.5 [Q8WY36-2] C9JE62 C9JZA0 C9J067 ENST00000456419.5 ENST00000415149.6 [Q8WY36-2] ENST00000443253.1 C9JSH4 ENST00000425868.5 C9J0J4 ENST00000413213.5 C9K0D1 ENST00000429270.1 ENST00000431630.5 ENST00000402543.5 ENST00000458458.5 ENST00000416476.6 [Q8WY36-3] C9IYG9 C9JNU3 ENST00000449335.5 ENST00000456817.5 ENST00000454540.5 H7C1U1 ENST00000449271.5 ENST00000402163.6 C9JA69 C9JIZ2 ENST00000427402.5

GO_0060348	Biological process	bone development
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0000977	Molecular function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific

BBX report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review