negative regulation of ossification

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1CALCA-CALCRCALC_HUMAN - CALCR_HUMANLigand-ReceptorSignaling by Calcitonin
2DKK1-KREMEN1+LRP6DKK1_HUMAN - Ligand-ReceptorSignaling by WNT inhibition
3DKK1-KREMEN2+LRP6DKK1_HUMAN - Ligand-ReceptorSignaling by WNT inhibition

II. Literature review

[source]
Namenegative regulation of ossification
IDGO_0030279
collection_id

Biological process

Exact synonym

down regulation of ossification, down-regulation of ossification, downregulation of ossification, negative regulation of bone biosynthesis, negative regulation of bone formation

Description

Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.

External URL
Genes
TMEM53CHSY1TPH1SFRP1BCL2GFRA4LRP4DKK1SOX9TGFB1NOTCH1MDKMEF2CCALCRRBPJSMAD6KREMEN2KREMEN1SMAD7CALCASOST