TPH1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TPH1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TPH1 at tissue level.

III. Associated gene sets

GO_0030279Biological processnegative regulation of ossification
GO_0002576Biological processplatelet degranulation
GO_0035902Biological processresponse to immobilization stress
GO_0046849Biological processbone remodeling
GO_0042427Biological processserotonin biosynthetic process
GO_1900046Biological processregulation of hemostasis
GO_0060749Biological processmammary gland alveolus development
GO_0009072Biological processaromatic amino acid metabolic process
GO_0045600Biological processpositive regulation of fat cell differentiation
GO_0007623Biological processcircadian rhythm
GO_0005829Cellular componentcytosol
GO_0043005Cellular componentneuron projection
GO_0005506Molecular functioniron ion binding
GO_0005515Molecular functionprotein binding
GO_0004510Molecular functiontryptophan 5-monooxygenase activity

IV. Literature review

[source]
Gene nameTPH1
Protein nameTPH1 protein
Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1)
Tryptophan hydroxylase 1
SynonymsTPH
TRPH
TPRH
DescriptionFUNCTION: Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. .

FUNCTION: Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. .

FUNCTION: Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. .

FUNCTION: Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. .

AccessionsENST00000528338.1
ENST00000250018.6 [P17752-1]
E7EMX4
B3VRX5
B3VRY5
B3VRZ0
P17752
B3VRY0
Q08EN2
B3VRW5
B3VS05
ENST00000682019.1 [P17752-1]
B3VS10
B3VRX0
B3VS00
E9PR49
B3VRZ5
ENST00000417164.5