Insufficient scRNA-seq data for expression of TPH1 at single-cell level.
Insufficient scRNA-seq data for expression of TPH1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 96% | 239.72 | 236 / 245 | 39% | 1.24 | 195 / 502 |
breast | 97% | 190.17 | 445 / 459 | 19% | 3.34 | 211 / 1118 |
thymus | 93% | 136.63 | 607 / 653 | 20% | 0.42 | 118 / 605 |
stomach | 95% | 587.58 | 341 / 359 | 14% | 0.54 | 39 / 286 |
intestine | 92% | 399.33 | 886 / 966 | 12% | 2.45 | 61 / 527 |
uterus | 95% | 168.72 | 162 / 170 | 3% | 0.31 | 16 / 459 |
blood vessel | 99% | 1595.39 | 1316 / 1335 | 0% | 0 | 0 / 0 |
spleen | 97% | 185.54 | 234 / 241 | 0% | 0 | 0 / 0 |
ovary | 92% | 175.97 | 166 / 180 | 3% | 0.05 | 12 / 430 |
lung | 85% | 105.28 | 489 / 578 | 9% | 0.41 | 108 / 1155 |
adipose | 90% | 130.12 | 1080 / 1204 | 0% | 0 | 0 / 0 |
pancreas | 74% | 70.89 | 244 / 328 | 13% | 1.06 | 23 / 178 |
skin | 82% | 142.84 | 1486 / 1809 | 4% | 0.06 | 18 / 472 |
bladder | 76% | 100.14 | 16 / 21 | 5% | 2.55 | 27 / 504 |
esophagus | 62% | 55.83 | 892 / 1445 | 15% | 3.55 | 28 / 183 |
brain | 52% | 45.01 | 1367 / 2642 | 22% | 0.47 | 153 / 705 |
kidney | 64% | 69.39 | 57 / 89 | 7% | 0.11 | 61 / 901 |
adrenal gland | 37% | 26.05 | 96 / 258 | 19% | 3.24 | 43 / 230 |
muscle | 56% | 51.42 | 448 / 803 | 0% | 0 | 0 / 0 |
heart | 45% | 36.24 | 388 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 19% | 17.57 | 177 / 929 | 0% | 0 | 0 / 0 |
liver | 14% | 8.49 | 32 / 226 | 3% | 0.09 | 14 / 406 |
tonsil | 0% | 0 | 0 / 0 | 4% | 0.06 | 2 / 45 |
eye | 0% | 0 | 0 / 0 | 4% | 0.05 | 3 / 80 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.05 | 1 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030279 | Biological process | negative regulation of ossification |
GO_0002576 | Biological process | platelet degranulation |
GO_0035902 | Biological process | response to immobilization stress |
GO_0046849 | Biological process | bone remodeling |
GO_0042427 | Biological process | serotonin biosynthetic process |
GO_1900046 | Biological process | regulation of hemostasis |
GO_0060749 | Biological process | mammary gland alveolus development |
GO_0009072 | Biological process | aromatic amino acid metabolic process |
GO_0045600 | Biological process | positive regulation of fat cell differentiation |
GO_0007623 | Biological process | circadian rhythm |
GO_0005829 | Cellular component | cytosol |
GO_0043005 | Cellular component | neuron projection |
GO_0005506 | Molecular function | iron ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0004510 | Molecular function | tryptophan 5-monooxygenase activity |
Gene name | TPH1 |
Protein name | TPH1 protein Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1) Tryptophan hydroxylase 1 |
Synonyms | TPH TRPH TPRH |
Description | FUNCTION: Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. . FUNCTION: Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. . FUNCTION: Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. . FUNCTION: Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. . |
Accessions | ENST00000528338.1 ENST00000250018.6 [P17752-1] E7EMX4 B3VRX5 B3VRY5 B3VRZ0 P17752 B3VRY0 Q08EN2 B3VRW5 B3VS05 ENST00000682019.1 [P17752-1] B3VS10 B3VRX0 B3VS00 E9PR49 B3VRZ5 ENST00000417164.5 |