Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 30 studies | 28% ± 11% | |
| pericyte | 15 studies | 28% ± 12% | |
| macrophage | 11 studies | 30% ± 14% | |
| fibroblast | 11 studies | 24% ± 7% | |
| smooth muscle cell | 10 studies | 23% ± 5% | |
| microglial cell | 10 studies | 33% ± 11% | |
| endothelial cell of artery | 8 studies | 24% ± 6% | |
| myeloid cell | 7 studies | 24% ± 7% | |
| astrocyte | 7 studies | 29% ± 13% | |
| mast cell | 6 studies | 21% ± 3% | |
| endothelial cell of vascular tree | 6 studies | 28% ± 16% | |
| endothelial cell of lymphatic vessel | 5 studies | 20% ± 2% | |
| vein endothelial cell | 5 studies | 32% ± 12% | |
| monocyte | 4 studies | 23% ± 6% | |
| classical monocyte | 4 studies | 22% ± 1% | |
| lymphocyte | 4 studies | 18% ± 4% | |
| hematopoietic precursor cell | 3 studies | 22% ± 9% | |
| dendritic cell | 3 studies | 22% ± 3% | |
| endocardial cell | 3 studies | 44% ± 9% | |
| non-classical monocyte | 3 studies | 20% ± 0% | |
| epithelial cell | 3 studies | 27% ± 6% | |
| GABAergic neuron | 3 studies | 44% ± 7% | |
| glutamatergic neuron | 3 studies | 51% ± 10% | |
| connective tissue cell | 3 studies | 23% ± 4% | |
| oligodendrocyte | 3 studies | 21% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 7 studies | 31% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 3478.36 | 245 / 245 | 100% | 40.22 | 501 / 502 |
| breast | 100% | 4687.62 | 459 / 459 | 100% | 57.00 | 1115 / 1118 |
| lung | 100% | 5381.86 | 577 / 578 | 99% | 35.21 | 1142 / 1155 |
| esophagus | 100% | 1844.93 | 1443 / 1445 | 98% | 32.68 | 180 / 183 |
| skin | 100% | 3502.91 | 1808 / 1809 | 98% | 50.94 | 461 / 472 |
| uterus | 100% | 3149.92 | 170 / 170 | 97% | 33.84 | 446 / 459 |
| bladder | 100% | 2424.19 | 21 / 21 | 97% | 24.74 | 488 / 504 |
| thymus | 100% | 2564.00 | 650 / 653 | 96% | 20.72 | 582 / 605 |
| kidney | 100% | 2097.94 | 89 / 89 | 95% | 38.27 | 860 / 901 |
| adrenal gland | 100% | 3688.15 | 258 / 258 | 95% | 30.02 | 219 / 230 |
| ovary | 100% | 4479.24 | 180 / 180 | 95% | 22.63 | 409 / 430 |
| stomach | 100% | 1892.34 | 358 / 359 | 94% | 23.22 | 270 / 286 |
| brain | 93% | 1270.13 | 2468 / 2642 | 100% | 27.02 | 704 / 705 |
| intestine | 99% | 1738.94 | 953 / 966 | 94% | 21.74 | 497 / 527 |
| pancreas | 55% | 487.93 | 181 / 328 | 98% | 34.94 | 174 / 178 |
| liver | 61% | 624.25 | 137 / 226 | 46% | 7.63 | 188 / 406 |
| adipose | 100% | 5292.93 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 5830.95 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2773.70 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.90 | 1 / 1 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 26.06 | 44 / 45 |
| heart | 96% | 2436.24 | 828 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 93% | 2642.62 | 867 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 16.71 | 27 / 29 |
| muscle | 75% | 777.81 | 599 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 70% | 9.62 | 56 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0045880 | Biological process | positive regulation of smoothened signaling pathway |
| GO_0030279 | Biological process | negative regulation of ossification |
| GO_0031667 | Biological process | response to nutrient levels |
| GO_0009954 | Biological process | proximal/distal pattern formation |
| GO_0060349 | Biological process | bone morphogenesis |
| GO_0030206 | Biological process | chondroitin sulfate biosynthetic process |
| GO_0051923 | Biological process | sulfation |
| GO_0002063 | Biological process | chondrocyte development |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0032580 | Cellular component | Golgi cisterna membrane |
| GO_0005576 | Cellular component | extracellular region |
| GO_0016020 | Cellular component | membrane |
| GO_0050510 | Molecular function | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0047238 | Molecular function | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity |
| Gene name | CHSY1 |
| Protein name | Alternative protein CHSY1 Hexosyltransferase (EC 2.4.1.-) Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1) |
| Synonyms | CHSY UNQ756/PRO1487 CSS1 KIAA0990 |
| Description | FUNCTION: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling. . |
| Accessions | A0A2R8Y7B7 L8E844 ENST00000254190.4 ENST00000543813.2 Q86X52 |