GFRA4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GFRA4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GFRA4 at tissue level.

III. Associated gene sets

GO_0030279Biological processnegative regulation of ossification
GO_0001503Biological processossification
GO_0007399Biological processnervous system development
GO_0035860Biological processglial cell-derived neurotrophic factor receptor signaling pathway
GO_0009897Cellular componentexternal side of plasma membrane
GO_0043235Cellular componentreceptor complex
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0016167Molecular functionglial cell-derived neurotrophic factor receptor activity

IV. Literature review

[source]
Gene nameGFRA4
Protein nameGDNF family receptor alpha-4 (GDNF receptor alpha-4) (GDNFR-alpha-4) (GFR-alpha-4) (Persephin receptor)
Synonyms
DescriptionFUNCTION: Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.

AccessionsQ9GZZ7
ENST00000290417.7 [Q9GZZ7-2]
ENST00000319242.8 [Q9GZZ7-1]
ENST00000477160.1 [Q9GZZ7-3]