TSTD1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	34 studies	35% ± 13%	Explore
natural killer cell	33 studies	30% ± 9%	Explore
CD8-positive, alpha-beta T cell	31 studies	32% ± 11%	Explore
CD4-positive, alpha-beta T cell	29 studies	34% ± 11%	Explore
T cell	21 studies	30% ± 9%	Explore
epithelial cell	21 studies	47% ± 20%	Explore
regulatory T cell	21 studies	38% ± 12%	Explore
naive B cell	20 studies	35% ± 10%	Explore
memory B cell	19 studies	32% ± 9%	Explore
basal cell	17 studies	44% ± 18%	Explore
ciliated cell	16 studies	75% ± 17%	Explore
mature NK T cell	16 studies	33% ± 9%	Explore
gamma-delta T cell	16 studies	33% ± 10%	Explore
mast cell	14 studies	29% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	37% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	35% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	37% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	34% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	30% ± 11%	Explore
secretory cell	11 studies	52% ± 16%	Explore
mucosal invariant T cell	11 studies	30% ± 7%	Explore
plasma cell	10 studies	35% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	35% ± 10%	Explore
goblet cell	10 studies	44% ± 17%	Explore
plasmacytoid dendritic cell	10 studies	30% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	34% ± 13%	Explore
T follicular helper cell	8 studies	38% ± 6%	Explore
abnormal cell	8 studies	43% ± 20%	Explore
type I pneumocyte	7 studies	54% ± 11%	Explore
type II pneumocyte	7 studies	62% ± 20%	Explore
club cell	7 studies	52% ± 14%	Explore
innate lymphoid cell	6 studies	31% ± 7%	Explore
respiratory goblet cell	6 studies	37% ± 22%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	30% ± 8%	Explore
conventional dendritic cell	6 studies	22% ± 4%	Explore
epithelial cell of proximal tubule	6 studies	40% ± 11%	Explore
kidney loop of Henle epithelial cell	6 studies	47% ± 11%	Explore
enterocyte	6 studies	34% ± 13%	Explore
progenitor cell	6 studies	36% ± 15%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	37% ± 12%	Explore
CD4-positive helper T cell	5 studies	21% ± 7%	Explore
exhausted T cell	5 studies	42% ± 5%	Explore
ionocyte	5 studies	56% ± 9%	Explore
leukocyte	5 studies	23% ± 6%	Explore
renal alpha-intercalated cell	5 studies	53% ± 6%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	47% ± 11%	Explore
enteroendocrine cell	5 studies	36% ± 23%	Explore
mesothelial cell	5 studies	35% ± 17%	Explore
transit amplifying cell	5 studies	29% ± 14%	Explore
hematopoietic stem cell	5 studies	31% ± 10%	Explore
hematopoietic precursor cell	4 studies	41% ± 22%	Explore
duct epithelial cell	4 studies	60% ± 6%	Explore
pancreatic A cell	4 studies	42% ± 11%	Explore
type B pancreatic cell	4 studies	46% ± 10%	Explore
non-classical monocyte	4 studies	29% ± 6%	Explore
plasmablast	4 studies	36% ± 16%	Explore
intestinal crypt stem cell	4 studies	37% ± 11%	Explore
brush cell	4 studies	32% ± 18%	Explore
immature B cell	4 studies	41% ± 7%	Explore
mucus secreting cell	4 studies	47% ± 22%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	48% ± 4%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	72% ± 13%	Explore
T-helper 17 cell	4 studies	28% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	26% ± 8%	Explore
double negative thymocyte	4 studies	41% ± 13%	Explore
deuterosomal cell	3 studies	46% ± 1%	Explore
IgG plasma cell	3 studies	16% ± 1%	Explore
renal principal cell	3 studies	57% ± 11%	Explore
neuroendocrine cell	3 studies	49% ± 17%	Explore
retinal cone cell	3 studies	34% ± 19%	Explore
serous secreting cell	3 studies	53% ± 19%	Explore
intraepithelial lymphocyte	3 studies	35% ± 8%	Explore
myoepithelial cell	3 studies	36% ± 5%	Explore
luminal cell of prostate epithelium	3 studies	71% ± 7%	Explore
dendritic cell	3 studies	35% ± 6%	Explore
granulocyte	3 studies	28% ± 10%	Explore
hepatocyte	3 studies	43% ± 32%	Explore
group 3 innate lymphoid cell	3 studies	35% ± 12%	Explore
keratinocyte	3 studies	23% ± 2%	Explore
T-helper 1 cell	3 studies	40% ± 6%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	41% ± 9%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	36% ± 12%	Explore
progenitor cell of mammary luminal epithelium	3 studies	45% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	27% ± 8%	Explore
lung	14 studies	32% ± 17%	Explore
kidney	8 studies	26% ± 9%	Explore
intestine	8 studies	26% ± 12%	Explore
lymph node	5 studies	30% ± 5%	Explore
pancreas	4 studies	39% ± 9%	Explore
prostate	4 studies	36% ± 12%	Explore
breast	4 studies	31% ± 8%	Explore
placenta	3 studies	32% ± 7%	Explore
uterus	3 studies	38% ± 17%	Explore
thymus	3 studies	41% ± 15%	Explore
brain	3 studies	18% ± 2%	Explore
liver	3 studies	28% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	3340.92	653 / 653	100%	220.05	604 / 605
prostate	99%	2296.48	243 / 245	100%	194.68	501 / 502
pancreas	100%	1108.14	328 / 328	98%	73.05	174 / 178
ovary	97%	1123.31	174 / 180	99%	118.34	427 / 430
breast	96%	1303.93	440 / 459	99%	167.18	1106 / 1118
lung	99%	1093.07	570 / 578	95%	71.12	1102 / 1155
kidney	100%	2196.72	89 / 89	92%	49.57	830 / 901
liver	99%	834.31	224 / 226	92%	64.52	374 / 406
stomach	96%	953.47	346 / 359	86%	52.16	247 / 286
esophagus	90%	849.28	1307 / 1445	89%	42.15	162 / 183
intestine	82%	848.71	792 / 966	95%	73.02	502 / 527
adrenal gland	100%	1473.74	258 / 258	63%	30.45	144 / 230
bladder	57%	586.43	12 / 21	96%	111.41	484 / 504
uterus	27%	130.89	46 / 170	90%	86.76	414 / 459
spleen	100%	909.88	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	86.30	1 / 1
lymph node	0%	0	0 / 0	97%	95.92	28 / 29
skin	75%	1041.36	1355 / 1809	21%	9.78	99 / 472
brain	74%	520.39	1953 / 2642	22%	9.95	153 / 705
tonsil	0%	0	0 / 0	96%	58.57	43 / 45
peripheral blood	93%	925.01	864 / 929	0%	0	0 / 0
adipose	79%	484.21	950 / 1204	0%	0	0 / 0
blood vessel	78%	479.65	1047 / 1335	0%	0	0 / 0
muscle	74%	381.80	595 / 803	0%	0	0 / 0
heart	72%	465.88	620 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	4%	1.18	3 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0070221	Biological process	sulfide oxidation, using sulfide:quinone oxidoreductase
GO_0006006	Biological process	glucose metabolic process
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005829	Cellular component	cytosol
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005737	Cellular component	cytoplasm
GO_0036464	Cellular component	cytoplasmic ribonucleoprotein granule
GO_0044877	Molecular function	protein-containing complex binding
GO_0003690	Molecular function	double-stranded DNA binding
GO_0042802	Molecular function	identical protein binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0050337	Molecular function	thiosulfate-thiol sulfurtransferase activity
GO_0043565	Molecular function	sequence-specific DNA binding

IV. Literature review

[source]

Gene name	TSTD1
Protein name	Thiosulfate sulfurtransferase like domain containing 1 Thiosulfate:glutathione sulfurtransferase (TST) (EC 2.8.1.-)
Synonyms	KAT
Description	FUNCTION: Thiosulfate:glutathione sulfurtransferase (TST) required to produce S-sulfanylglutathione (GSS(-)), a central intermediate in hydrogen sulfide metabolism . Provides the link between the first step in mammalian H(2)S metabolism performed by the sulfide:quinone oxidoreductase (SQOR) which catalyzes the conversion of H(2)S to thiosulfate, and the sulfur dioxygenase (SDO) which uses GSS(-) as substrate . The thermodynamic coupling of the irreversible SDO and reversible TST reactions provides a model for the physiologically relevant reaction with thiosulfate as the sulfane donor . .
Accessions	R4GNF9 ENST00000466967.1 ENST00000368023.7 [Q8NFU3-4] Q8NFU3 ENST00000318289.14 [Q8NFU3-3] ENST00000423014.3 [Q8NFU3-1] ENST00000368024.5 [Q8NFU3-2]

TSTD1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review