TOMM22 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	31 studies	27% ± 10%	Explore
B cell	29 studies	28% ± 9%	Explore
CD4-positive, alpha-beta T cell	25 studies	31% ± 14%	Explore
T cell	24 studies	27% ± 9%	Explore
conventional dendritic cell	24 studies	33% ± 16%	Explore
CD8-positive, alpha-beta T cell	24 studies	32% ± 13%	Explore
regulatory T cell	20 studies	30% ± 11%	Explore
memory B cell	19 studies	28% ± 10%	Explore
classical monocyte	19 studies	28% ± 11%	Explore
non-classical monocyte	17 studies	30% ± 15%	Explore
naive B cell	17 studies	26% ± 6%	Explore
endothelial cell	17 studies	29% ± 12%	Explore
fibroblast	17 studies	26% ± 11%	Explore
macrophage	17 studies	23% ± 9%	Explore
basal cell	14 studies	29% ± 16%	Explore
pericyte	14 studies	26% ± 9%	Explore
gamma-delta T cell	14 studies	31% ± 14%	Explore
plasmacytoid dendritic cell	14 studies	32% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	27% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	27% ± 7%	Explore
mature NK T cell	13 studies	27% ± 7%	Explore
epithelial cell	13 studies	39% ± 20%	Explore
plasma cell	12 studies	32% ± 16%	Explore
connective tissue cell	12 studies	28% ± 11%	Explore
monocyte	12 studies	27% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	28% ± 13%	Explore
dendritic cell	11 studies	43% ± 24%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	33% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	32% ± 8%	Explore
smooth muscle cell	11 studies	29% ± 8%	Explore
mast cell	9 studies	20% ± 2%	Explore
plasmablast	9 studies	42% ± 22%	Explore
mucosal invariant T cell	9 studies	32% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	32% ± 9%	Explore
progenitor cell	8 studies	36% ± 8%	Explore
abnormal cell	8 studies	27% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	30% ± 10%	Explore
myofibroblast cell	7 studies	33% ± 3%	Explore
goblet cell	7 studies	24% ± 13%	Explore
vein endothelial cell	7 studies	24% ± 6%	Explore
ciliated cell	7 studies	35% ± 15%	Explore
endothelial cell of lymphatic vessel	7 studies	29% ± 9%	Explore
T follicular helper cell	7 studies	24% ± 5%	Explore
endothelial cell of vascular tree	7 studies	24% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	36% ± 15%	Explore
epithelial cell of proximal tubule	6 studies	23% ± 7%	Explore
endothelial cell of artery	6 studies	21% ± 4%	Explore
hematopoietic stem cell	6 studies	31% ± 12%	Explore
precursor B cell	6 studies	38% ± 10%	Explore
innate lymphoid cell	6 studies	25% ± 6%	Explore
hematopoietic precursor cell	5 studies	45% ± 19%	Explore
enteroendocrine cell	5 studies	30% ± 13%	Explore
intestinal crypt stem cell	5 studies	29% ± 7%	Explore
mesothelial cell	5 studies	37% ± 16%	Explore
transit amplifying cell	5 studies	26% ± 6%	Explore
erythroblast	5 studies	39% ± 16%	Explore
pro-B cell	5 studies	37% ± 6%	Explore
capillary endothelial cell	5 studies	24% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	33% ± 12%	Explore
leukocyte	4 studies	29% ± 7%	Explore
mononuclear phagocyte	4 studies	31% ± 14%	Explore
exhausted T cell	4 studies	35% ± 9%	Explore
myeloid cell	4 studies	31% ± 11%	Explore
immature B cell	4 studies	42% ± 13%	Explore
neuron	4 studies	44% ± 15%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	42% ± 6%	Explore
intermediate monocyte	4 studies	39% ± 18%	Explore
erythrocyte	4 studies	40% ± 21%	Explore
secretory cell	4 studies	30% ± 17%	Explore
T-helper 17 cell	4 studies	33% ± 22%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	25% ± 7%	Explore
precursor cell	3 studies	46% ± 10%	Explore
pancreatic A cell	3 studies	32% ± 10%	Explore
kidney loop of Henle epithelial cell	3 studies	23% ± 2%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	38% ± 16%	Explore
renal alpha-intercalated cell	3 studies	28% ± 7%	Explore
enterocyte	3 studies	21% ± 1%	Explore
neural crest cell	3 studies	39% ± 5%	Explore
common myeloid progenitor	3 studies	40% ± 19%	Explore
lymphocyte	3 studies	31% ± 10%	Explore
club cell	3 studies	24% ± 9%	Explore
type I pneumocyte	3 studies	31% ± 8%	Explore
type II pneumocyte	3 studies	34% ± 15%	Explore
serous secreting cell	3 studies	21% ± 1%	Explore
germinal center B cell	3 studies	35% ± 2%	Explore
myoepithelial cell	3 studies	27% ± 4%	Explore
pancreatic ductal cell	3 studies	38% ± 9%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	46% ± 28%	Explore
group 3 innate lymphoid cell	3 studies	34% ± 13%	Explore
keratinocyte	3 studies	24% ± 7%	Explore
T-helper 1 cell	3 studies	36% ± 8%	Explore
double negative thymocyte	3 studies	47% ± 18%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	24% ± 3%	Explore
progenitor cell of mammary luminal epithelium	3 studies	18% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	32% ± 9%	Explore
lung	10 studies	31% ± 13%	Explore
intestine	9 studies	27% ± 12%	Explore
kidney	6 studies	25% ± 5%	Explore
lymph node	5 studies	27% ± 7%	Explore
pancreas	3 studies	34% ± 7%	Explore
bone marrow	3 studies	24% ± 4%	Explore
liver	3 studies	33% ± 23%	Explore
brain	3 studies	16% ± 1%	Explore
breast	3 studies	20% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2377.25	1445 / 1445	100%	71.11	183 / 183
kidney	100%	2365.54	89 / 89	100%	95.11	901 / 901
liver	100%	1635.56	226 / 226	100%	94.03	406 / 406
lung	100%	1786.60	578 / 578	100%	135.76	1155 / 1155
ovary	100%	2039.66	180 / 180	100%	97.81	430 / 430
prostate	100%	2020.39	245 / 245	100%	112.40	502 / 502
skin	100%	3114.33	1809 / 1809	100%	152.64	472 / 472
stomach	100%	1995.94	359 / 359	100%	102.80	286 / 286
breast	100%	2277.78	459 / 459	100%	112.47	1116 / 1118
brain	100%	1908.72	2637 / 2642	100%	104.20	705 / 705
intestine	100%	2540.44	966 / 966	100%	129.07	526 / 527
bladder	100%	2302.90	21 / 21	100%	127.83	503 / 504
uterus	100%	2053.39	170 / 170	100%	132.80	458 / 459
pancreas	100%	1434.99	327 / 328	100%	92.15	178 / 178
thymus	100%	1828.74	653 / 653	100%	98.43	603 / 605
adrenal gland	100%	2556.74	258 / 258	98%	70.24	225 / 230
adipose	100%	2317.91	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	135.58	80 / 80
lymph node	0%	0	0 / 0	100%	177.33	29 / 29
muscle	100%	2093.91	803 / 803	0%	0	0 / 0
spleen	100%	2199.65	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	137.14	45 / 45
ureter	0%	0	0 / 0	100%	112.26	1 / 1
blood vessel	100%	1793.82	1334 / 1335	0%	0	0 / 0
heart	98%	2040.72	848 / 861	0%	0	0 / 0
peripheral blood	95%	1980.39	887 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006626	Biological process	protein targeting to mitochondrion
GO_0045040	Biological process	protein insertion into mitochondrial outer membrane
GO_0071806	Biological process	protein transmembrane transport
GO_0005741	Cellular component	mitochondrial outer membrane
GO_0140596	Cellular component	TOM complex
GO_0005742	Cellular component	mitochondrial outer membrane translocase complex
GO_0016020	Cellular component	membrane
GO_0005739	Cellular component	mitochondrion
GO_0008320	Molecular function	protein transmembrane transporter activity
GO_0030943	Molecular function	mitochondrion targeting sequence binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	TOMM22
Protein name	Mitochondrial import receptor subunit TOM22 homolog (hTom22) (1C9-2) (Translocase of outer membrane 22 kDa subunit homolog)
Synonyms	TOM22
Description	FUNCTION: Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore . Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases (By similarity). .
Accessions	Q9NS69 ENST00000216034.6

TOMM22 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review