SELENOF | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	37 studies	40% ± 15%	Explore
endothelial cell	35 studies	33% ± 15%	Explore
B cell	33 studies	35% ± 11%	Explore
natural killer cell	31 studies	31% ± 8%	Explore
macrophage	30 studies	29% ± 11%	Explore
CD8-positive, alpha-beta T cell	28 studies	31% ± 9%	Explore
CD4-positive, alpha-beta T cell	26 studies	30% ± 8%	Explore
T cell	25 studies	29% ± 9%	Explore
conventional dendritic cell	25 studies	33% ± 16%	Explore
pericyte	23 studies	34% ± 13%	Explore
smooth muscle cell	22 studies	26% ± 9%	Explore
monocyte	19 studies	28% ± 10%	Explore
plasmacytoid dendritic cell	19 studies	51% ± 15%	Explore
classical monocyte	19 studies	30% ± 11%	Explore
regulatory T cell	19 studies	32% ± 7%	Explore
naive B cell	18 studies	37% ± 8%	Explore
non-classical monocyte	18 studies	32% ± 13%	Explore
basal cell	18 studies	32% ± 15%	Explore
epithelial cell	18 studies	37% ± 20%	Explore
memory B cell	17 studies	34% ± 7%	Explore
endothelial cell of lymphatic vessel	16 studies	34% ± 12%	Explore
mature NK T cell	15 studies	32% ± 8%	Explore
plasma cell	14 studies	41% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	33% ± 7%	Explore
ciliated cell	14 studies	38% ± 17%	Explore
connective tissue cell	14 studies	38% ± 15%	Explore
gamma-delta T cell	14 studies	34% ± 13%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	28% ± 6%	Explore
dendritic cell	13 studies	37% ± 23%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	32% ± 9%	Explore
myofibroblast cell	12 studies	39% ± 10%	Explore
mesothelial cell	12 studies	40% ± 17%	Explore
endothelial cell of vascular tree	12 studies	31% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	34% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	35% ± 6%	Explore
vein endothelial cell	11 studies	32% ± 8%	Explore
mucosal invariant T cell	11 studies	33% ± 8%	Explore
myeloid cell	11 studies	31% ± 13%	Explore
plasmablast	10 studies	41% ± 24%	Explore
secretory cell	10 studies	27% ± 7%	Explore
capillary endothelial cell	10 studies	34% ± 7%	Explore
goblet cell	10 studies	31% ± 16%	Explore
type I pneumocyte	9 studies	31% ± 11%	Explore
type II pneumocyte	9 studies	33% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	35% ± 9%	Explore
club cell	9 studies	29% ± 12%	Explore
abnormal cell	9 studies	25% ± 6%	Explore
endothelial cell of artery	9 studies	35% ± 9%	Explore
mast cell	9 studies	20% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	29% ± 10%	Explore
progenitor cell	8 studies	29% ± 9%	Explore
astrocyte	8 studies	32% ± 14%	Explore
alveolar macrophage	7 studies	24% ± 7%	Explore
leukocyte	7 studies	27% ± 6%	Explore
neuron	7 studies	32% ± 14%	Explore
enterocyte	7 studies	20% ± 4%	Explore
T follicular helper cell	7 studies	35% ± 5%	Explore
precursor B cell	7 studies	48% ± 13%	Explore
microglial cell	7 studies	26% ± 11%	Explore
oligodendrocyte	7 studies	26% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	34% ± 5%	Explore
mononuclear phagocyte	6 studies	35% ± 15%	Explore
transit amplifying cell	6 studies	22% ± 9%	Explore
adipocyte	6 studies	22% ± 6%	Explore
hematopoietic precursor cell	5 studies	42% ± 15%	Explore
ionocyte	5 studies	25% ± 7%	Explore
respiratory goblet cell	5 studies	32% ± 23%	Explore
glutamatergic neuron	5 studies	44% ± 19%	Explore
hematopoietic stem cell	5 studies	27% ± 5%	Explore
pro-B cell	5 studies	51% ± 8%	Explore
immature B cell	5 studies	45% ± 11%	Explore
retinal cone cell	5 studies	46% ± 28%	Explore
retinal rod cell	5 studies	34% ± 19%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	33% ± 14%	Explore
oligodendrocyte precursor cell	5 studies	29% ± 7%	Explore
deuterosomal cell	4 studies	19% ± 5%	Explore
exhausted T cell	4 studies	40% ± 5%	Explore
epithelial cell of proximal tubule	4 studies	20% ± 4%	Explore
kidney loop of Henle epithelial cell	4 studies	29% ± 5%	Explore
intestinal crypt stem cell	4 studies	26% ± 7%	Explore
lymphocyte	4 studies	33% ± 11%	Explore
innate lymphoid cell	4 studies	31% ± 5%	Explore
retina horizontal cell	4 studies	30% ± 8%	Explore
Mueller cell	4 studies	31% ± 14%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	38% ± 2%	Explore
CD4-positive helper T cell	4 studies	24% ± 6%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	41% ± 6%	Explore
luminal cell of prostate epithelium	4 studies	24% ± 8%	Explore
GABAergic neuron	4 studies	42% ± 11%	Explore
enteroendocrine cell	4 studies	36% ± 18%	Explore
duct epithelial cell	3 studies	29% ± 1%	Explore
pancreatic A cell	3 studies	58% ± 18%	Explore
type B pancreatic cell	3 studies	57% ± 26%	Explore
glomerular endothelial cell	3 studies	37% ± 7%	Explore
neural crest cell	3 studies	25% ± 1%	Explore
IgA plasma cell	3 studies	22% ± 4%	Explore
IgG plasma cell	3 studies	26% ± 2%	Explore
extravillous trophoblast	3 studies	43% ± 20%	Explore
placental villous trophoblast	3 studies	35% ± 19%	Explore
megakaryocyte	3 studies	20% ± 6%	Explore
amacrine cell	3 studies	41% ± 10%	Explore
adventitial cell	3 studies	40% ± 16%	Explore
tissue-resident macrophage	3 studies	26% ± 10%	Explore
intraepithelial lymphocyte	3 studies	36% ± 17%	Explore
rod bipolar cell	3 studies	25% ± 3%	Explore
erythroblast	3 studies	43% ± 17%	Explore
germinal center B cell	3 studies	38% ± 8%	Explore
intermediate monocyte	3 studies	41% ± 18%	Explore
myoepithelial cell	3 studies	38% ± 9%	Explore
glial cell	3 studies	37% ± 19%	Explore
group 3 innate lymphoid cell	3 studies	44% ± 13%	Explore
T-helper 17 cell	3 studies	34% ± 8%	Explore
interneuron	3 studies	43% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	32% ± 8%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	30% ± 11%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	28% ± 11%	Explore
double negative thymocyte	3 studies	46% ± 14%	Explore
progenitor cell of mammary luminal epithelium	3 studies	29% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	17 studies	34% ± 13%	Explore
peripheral blood	17 studies	32% ± 11%	Explore
intestine	10 studies	27% ± 14%	Explore
brain	8 studies	34% ± 14%	Explore
kidney	7 studies	27% ± 4%	Explore
eye	7 studies	31% ± 16%	Explore
liver	6 studies	32% ± 17%	Explore
placenta	5 studies	31% ± 17%	Explore
bone marrow	5 studies	26% ± 8%	Explore
uterus	5 studies	37% ± 16%	Explore
prostate	4 studies	21% ± 5%	Explore
lymph node	4 studies	28% ± 5%	Explore
breast	4 studies	33% ± 4%	Explore
pancreas	3 studies	55% ± 24%	Explore
skin	3 studies	25% ± 7%	Explore
thymus	3 studies	47% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4272.73	1445 / 1445	100%	170.92	183 / 183
lung	100%	6845.83	578 / 578	100%	274.23	1155 / 1155
ovary	100%	5909.03	180 / 180	100%	261.58	430 / 430
pancreas	100%	3163.96	328 / 328	100%	243.14	178 / 178
thymus	100%	8746.38	653 / 653	100%	387.34	604 / 605
breast	100%	6876.31	459 / 459	100%	255.04	1116 / 1118
bladder	100%	5304.33	21 / 21	100%	247.53	503 / 504
prostate	100%	5360.36	245 / 245	100%	246.59	501 / 502
brain	100%	4109.04	2640 / 2642	100%	220.12	704 / 705
liver	100%	4157.75	226 / 226	100%	149.25	405 / 406
uterus	100%	6162.46	170 / 170	100%	234.68	457 / 459
stomach	100%	4211.01	359 / 359	99%	212.83	284 / 286
intestine	100%	4848.76	966 / 966	99%	239.98	522 / 527
kidney	100%	5146.18	89 / 89	99%	203.28	891 / 901
adrenal gland	100%	7981.59	258 / 258	97%	146.49	223 / 230
skin	100%	5925.43	1804 / 1809	95%	217.57	450 / 472
adipose	100%	6962.98	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	197.82	29 / 29
spleen	100%	5741.36	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	181.94	45 / 45
ureter	0%	0	0 / 0	100%	114.94	1 / 1
blood vessel	100%	5421.52	1331 / 1335	0%	0	0 / 0
heart	99%	3127.18	849 / 861	0%	0	0 / 0
peripheral blood	98%	5743.73	907 / 929	0%	0	0 / 0
muscle	97%	1910.21	776 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	79%	89.48	63 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	SELENOF
Protein name	Selenoprotein F Selenoprotein F (15 kDa selenoprotein)
Synonyms	SEP15
Description	FUNCTION: May be involved in redox reactions associated with the formation of disulfide bonds (By similarity). May contribute to the quality control of protein folding in the endoplasmic reticulum . May regulate protein folding by enhancing the catalytic activity of UGGT1/UGCGL1 and UGGT2/UGCGL2 . .
Accessions	ENST00000401030.4 A0A0J9YXM9 ENST00000467557.1 A0A3B3IT39 ENST00000497861.5 ENST00000370554.5 [O60613-2] A8MZD0 ENST00000648872.1 A0A0J9YX89 ENST00000331835.10 [O60613-1] O60613

GO_0035092	Biological process	sperm DNA condensation
GO_0098869	Biological process	cellular oxidant detoxification
GO_0051084	Biological process	'de novo' post-translational protein folding
GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0016491	Molecular function	oxidoreductase activity
GO_0008430	Molecular function	selenium binding
GO_0005515	Molecular function	protein binding
GO_0008379	Molecular function	thioredoxin peroxidase activity

SELENOF report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review