RNH1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	36 studies	38% ± 16%	Explore
macrophage	33 studies	41% ± 17%	Explore
endothelial cell	32 studies	33% ± 13%	Explore
conventional dendritic cell	28 studies	56% ± 19%	Explore
pericyte	27 studies	37% ± 12%	Explore
B cell	25 studies	22% ± 6%	Explore
natural killer cell	25 studies	23% ± 6%	Explore
classical monocyte	25 studies	45% ± 15%	Explore
CD4-positive, alpha-beta T cell	24 studies	25% ± 7%	Explore
CD8-positive, alpha-beta T cell	24 studies	23% ± 6%	Explore
smooth muscle cell	23 studies	36% ± 12%	Explore
non-classical monocyte	23 studies	65% ± 15%	Explore
dendritic cell	21 studies	56% ± 23%	Explore
monocyte	20 studies	40% ± 13%	Explore
basal cell	20 studies	38% ± 14%	Explore
T cell	18 studies	22% ± 5%	Explore
regulatory T cell	18 studies	23% ± 5%	Explore
epithelial cell	17 studies	35% ± 18%	Explore
connective tissue cell	17 studies	35% ± 13%	Explore
endothelial cell of lymphatic vessel	15 studies	40% ± 12%	Explore
memory B cell	14 studies	24% ± 6%	Explore
plasmacytoid dendritic cell	14 studies	28% ± 9%	Explore
ciliated cell	13 studies	33% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	21% ± 5%	Explore
myofibroblast cell	13 studies	38% ± 10%	Explore
myeloid cell	13 studies	44% ± 16%	Explore
gamma-delta T cell	13 studies	25% ± 7%	Explore
capillary endothelial cell	12 studies	29% ± 6%	Explore
mast cell	11 studies	26% ± 3%	Explore
plasma cell	11 studies	36% ± 10%	Explore
naive B cell	11 studies	19% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	25% ± 6%	Explore
mature NK T cell	11 studies	24% ± 5%	Explore
mesothelial cell	11 studies	45% ± 19%	Explore
vein endothelial cell	11 studies	29% ± 4%	Explore
endothelial cell of vascular tree	11 studies	32% ± 9%	Explore
type I pneumocyte	10 studies	43% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	26% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	25% ± 4%	Explore
endothelial cell of artery	10 studies	30% ± 5%	Explore
mucosal invariant T cell	10 studies	23% ± 4%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	24% ± 5%	Explore
secretory cell	9 studies	32% ± 9%	Explore
abnormal cell	9 studies	30% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	25% ± 7%	Explore
club cell	8 studies	29% ± 8%	Explore
leukocyte	8 studies	26% ± 7%	Explore
type II pneumocyte	7 studies	34% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	28% ± 9%	Explore
alveolar macrophage	6 studies	53% ± 11%	Explore
plasmablast	6 studies	45% ± 22%	Explore
ionocyte	6 studies	29% ± 10%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	24% ± 6%	Explore
mononuclear phagocyte	6 studies	45% ± 17%	Explore
epithelial cell of proximal tubule	6 studies	24% ± 5%	Explore
oligodendrocyte	6 studies	35% ± 14%	Explore
innate lymphoid cell	6 studies	28% ± 10%	Explore
T follicular helper cell	6 studies	22% ± 4%	Explore
platelet	5 studies	21% ± 7%	Explore
kidney loop of Henle epithelial cell	5 studies	28% ± 9%	Explore
renal alpha-intercalated cell	5 studies	39% ± 6%	Explore
retinal rod cell	5 studies	22% ± 9%	Explore
intermediate monocyte	5 studies	59% ± 14%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	31% ± 10%	Explore
goblet cell	5 studies	28% ± 7%	Explore
pancreatic A cell	4 studies	35% ± 16%	Explore
retinal ganglion cell	4 studies	52% ± 27%	Explore
erythroblast	4 studies	31% ± 13%	Explore
astrocyte	4 studies	34% ± 15%	Explore
retina horizontal cell	4 studies	31% ± 11%	Explore
adventitial cell	4 studies	55% ± 10%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	28% ± 1%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	33% ± 10%	Explore
neuron	4 studies	34% ± 14%	Explore
enteroendocrine cell	4 studies	32% ± 16%	Explore
T-helper 17 cell	4 studies	27% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	22% ± 6%	Explore
duct epithelial cell	3 studies	24% ± 9%	Explore
respiratory goblet cell	3 studies	25% ± 5%	Explore
hematopoietic precursor cell	3 studies	41% ± 1%	Explore
glomerular endothelial cell	3 studies	22% ± 3%	Explore
progenitor cell	3 studies	23% ± 5%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	26% ± 8%	Explore
retinal bipolar neuron	3 studies	31% ± 8%	Explore
lymphocyte	3 studies	40% ± 5%	Explore
immature B cell	3 studies	21% ± 6%	Explore
microglial cell	3 studies	29% ± 13%	Explore
serous secreting cell	3 studies	26% ± 8%	Explore
tissue-resident macrophage	3 studies	32% ± 13%	Explore
intraepithelial lymphocyte	3 studies	23% ± 6%	Explore
Mueller cell	3 studies	29% ± 2%	Explore
exhausted T cell	3 studies	23% ± 5%	Explore
myoepithelial cell	3 studies	43% ± 11%	Explore
muscle cell	3 studies	35% ± 22%	Explore
intestinal crypt stem cell	3 studies	20% ± 6%	Explore
glial cell	3 studies	30% ± 13%	Explore
erythrocyte	3 studies	39% ± 16%	Explore
group 3 innate lymphoid cell	3 studies	30% ± 10%	Explore
melanocyte	3 studies	34% ± 6%	Explore
transit amplifying cell	3 studies	23% ± 8%	Explore
keratinocyte	3 studies	41% ± 12%	Explore
neutrophil	3 studies	21% ± 4%	Explore
T-helper 1 cell	3 studies	29% ± 3%	Explore
adipocyte	3 studies	25% ± 4%	Explore
double negative thymocyte	3 studies	28% ± 3%	Explore
progenitor cell of mammary luminal epithelium	3 studies	25% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	17 studies	35% ± 11%	Explore
peripheral blood	17 studies	32% ± 9%	Explore
intestine	9 studies	25% ± 11%	Explore
eye	8 studies	27% ± 9%	Explore
kidney	7 studies	27% ± 4%	Explore
brain	5 studies	27% ± 8%	Explore
liver	5 studies	28% ± 12%	Explore
placenta	4 studies	30% ± 15%	Explore
uterus	4 studies	42% ± 10%	Explore
lymph node	4 studies	30% ± 16%	Explore
breast	4 studies	30% ± 3%	Explore
pancreas	3 studies	36% ± 11%	Explore
bone marrow	3 studies	23% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	14163.22	1445 / 1445	100%	52.43	183 / 183
uterus	100%	12422.54	170 / 170	100%	83.51	459 / 459
kidney	100%	9578.82	89 / 89	100%	69.95	899 / 901
ovary	100%	10631.58	180 / 180	100%	45.12	429 / 430
thymus	100%	10954.54	652 / 653	100%	96.65	604 / 605
prostate	100%	9825.06	245 / 245	99%	83.76	499 / 502
intestine	100%	9703.56	966 / 966	99%	69.01	523 / 527
skin	100%	20909.59	1809 / 1809	99%	106.62	468 / 472
breast	100%	12360.14	459 / 459	99%	70.11	1108 / 1118
liver	100%	5465.35	225 / 226	100%	54.46	404 / 406
lung	100%	13963.57	577 / 578	99%	73.60	1146 / 1155
stomach	100%	7334.89	359 / 359	99%	57.93	283 / 286
adrenal gland	100%	11747.51	258 / 258	99%	60.69	227 / 230
bladder	100%	12871.14	21 / 21	99%	75.23	497 / 504
pancreas	99%	4583.52	324 / 328	99%	73.52	177 / 178
brain	98%	5478.76	2576 / 2642	100%	73.54	705 / 705
adipose	100%	14450.97	1204 / 1204	0%	0	0 / 0
blood vessel	100%	13847.57	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	126.07	80 / 80
lymph node	0%	0	0 / 0	100%	105.90	29 / 29
spleen	100%	10490.20	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	92.75	45 / 45
ureter	0%	0	0 / 0	100%	41.88	1 / 1
muscle	99%	7150.37	798 / 803	0%	0	0 / 0
heart	98%	10195.32	848 / 861	0%	0	0 / 0
peripheral blood	95%	6449.54	883 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0034315	Biological process	regulation of Arp2/3 complex-mediated actin nucleation
GO_0006402	Biological process	mRNA catabolic process
GO_0016477	Biological process	cell migration
GO_0045765	Biological process	regulation of angiogenesis
GO_0032311	Cellular component	angiogenin-PRI complex
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0030027	Cellular component	lamellipodium
GO_0005886	Cellular component	plasma membrane
GO_0005515	Molecular function	protein binding
GO_0008428	Molecular function	ribonuclease inhibitor activity

IV. Literature review

[source]

Gene name	RNH1
Protein name	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) Ribonuclease inhibitor (Placental ribonuclease inhibitor) (Placental RNase inhibitor) (Ribonuclease/angiogenin inhibitor 1) (RAI)
Synonyms	PRI RNH
Description	FUNCTION: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis. . FUNCTION: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis. . FUNCTION: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis. . FUNCTION: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis. . FUNCTION: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis. .
Accessions	ENST00000356187.9 ENST00000618184.3 ENST00000633418.1 ENST00000632527.1 ENST00000397604.7 ENST00000633464.1 ENST00000631828.1 ENST00000397615.6 ENST00000354420.7 ENST00000529306.5 ENST00000533410.5 ENST00000531540.5 ENST00000529768.5 E9PIK5 ENST00000531149.1 ENST00000631468.1 A0A0J9YXC4 E9PR82 ENST00000632954.1 ENST00000633732.1 E9PIM9 ENST00000527485.5 ENST00000631544.1 E9PLZ3 ENST00000438658.6 ENST00000633287.1 ENST00000529368.5 E9PMI1 ENST00000631652.1 ENST00000532055.5 ENST00000534797.5 ENST00000397614.5 ENST00000525701.5 ENST00000619599.4 ENST00000621211.2 P13489 ENST00000612988.4 ENST00000617351.4 E9PMJ3 ENST00000634214.1 ENST00000524464.5 E9PMA9 H0YCR7

RNH1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review