POLR2I report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_0006367Biological processtranscription initiation at RNA polymerase II promoter
GO_0001193Biological processmaintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
GO_0006283Biological processtranscription-coupled nucleotide-excision repair
GO_0005730Cellular componentnucleolus
GO_0005665Cellular componentRNA polymerase II, core complex
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding
GO_0003676Molecular functionnucleic acid binding
GO_0003899Molecular functionDNA-directed 5'-3' RNA polymerase activity

IV. Literature review

[source]
Gene namePOLR2I
Protein nameRNA polymerase II subunit I
DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5)
Synonyms
DescriptionFUNCTION: Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. POLR2I/RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template. .

AccessionsK7EKS1
K7EK49
K7ENX4
ENST00000221859.9
ENST00000586439.1
ENST00000585842.5
P36954
ENST00000592962.5