PHPT1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	33 studies	44% ± 19%	Explore
natural killer cell	30 studies	25% ± 8%	Explore
endothelial cell	28 studies	33% ± 13%	Explore
macrophage	26 studies	28% ± 10%	Explore
pericyte	25 studies	40% ± 16%	Explore
smooth muscle cell	24 studies	41% ± 16%	Explore
conventional dendritic cell	24 studies	33% ± 15%	Explore
non-classical monocyte	22 studies	30% ± 13%	Explore
classical monocyte	19 studies	28% ± 12%	Explore
plasma cell	18 studies	40% ± 17%	Explore
basal cell	18 studies	41% ± 19%	Explore
connective tissue cell	18 studies	47% ± 20%	Explore
epithelial cell	18 studies	54% ± 25%	Explore
monocyte	17 studies	28% ± 9%	Explore
CD8-positive, alpha-beta T cell	17 studies	26% ± 8%	Explore
dendritic cell	17 studies	36% ± 20%	Explore
T cell	16 studies	24% ± 10%	Explore
endothelial cell of lymphatic vessel	16 studies	40% ± 14%	Explore
plasmacytoid dendritic cell	16 studies	30% ± 10%	Explore
regulatory T cell	16 studies	26% ± 8%	Explore
ciliated cell	15 studies	49% ± 18%	Explore
gamma-delta T cell	14 studies	23% ± 9%	Explore
B cell	13 studies	20% ± 6%	Explore
CD4-positive, alpha-beta T cell	13 studies	25% ± 7%	Explore
myofibroblast cell	13 studies	44% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	27% ± 6%	Explore
secretory cell	12 studies	42% ± 22%	Explore
vein endothelial cell	11 studies	25% ± 9%	Explore
mast cell	10 studies	25% ± 8%	Explore
plasmablast	10 studies	40% ± 22%	Explore
progenitor cell	10 studies	52% ± 20%	Explore
myeloid cell	10 studies	35% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	24% ± 4%	Explore
mature NK T cell	9 studies	24% ± 6%	Explore
abnormal cell	9 studies	47% ± 22%	Explore
goblet cell	9 studies	45% ± 18%	Explore
type I pneumocyte	8 studies	40% ± 19%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	23% ± 7%	Explore
capillary endothelial cell	8 studies	24% ± 6%	Explore
endothelial cell of artery	8 studies	27% ± 10%	Explore
mesothelial cell	8 studies	53% ± 23%	Explore
endothelial cell of vascular tree	8 studies	28% ± 8%	Explore
type II pneumocyte	7 studies	54% ± 20%	Explore
club cell	7 studies	43% ± 15%	Explore
epithelial cell of proximal tubule	7 studies	49% ± 17%	Explore
memory B cell	7 studies	17% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	25% ± 9%	Explore
kidney loop of Henle epithelial cell	6 studies	43% ± 12%	Explore
renal alpha-intercalated cell	6 studies	59% ± 8%	Explore
enterocyte	6 studies	49% ± 18%	Explore
IgA plasma cell	6 studies	22% ± 6%	Explore
IgG plasma cell	6 studies	23% ± 7%	Explore
innate lymphoid cell	6 studies	22% ± 5%	Explore
neuron	6 studies	46% ± 20%	Explore
astrocyte	6 studies	37% ± 17%	Explore
alveolar macrophage	5 studies	31% ± 5%	Explore
hematopoietic precursor cell	5 studies	37% ± 14%	Explore
mononuclear phagocyte	5 studies	35% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	24% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	19% ± 3%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	55% ± 10%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	31% ± 9%	Explore
mucosal invariant T cell	5 studies	18% ± 1%	Explore
respiratory goblet cell	4 studies	37% ± 28%	Explore
exhausted T cell	4 studies	34% ± 6%	Explore
enteroendocrine cell	4 studies	62% ± 17%	Explore
intestinal crypt stem cell	4 studies	41% ± 16%	Explore
leukocyte	4 studies	30% ± 9%	Explore
transit amplifying cell	4 studies	46% ± 15%	Explore
retinal ganglion cell	4 studies	61% ± 25%	Explore
erythroblast	4 studies	41% ± 25%	Explore
hematopoietic stem cell	4 studies	29% ± 14%	Explore
brush cell	4 studies	28% ± 12%	Explore
amacrine cell	4 studies	38% ± 18%	Explore
retina horizontal cell	4 studies	41% ± 17%	Explore
adventitial cell	4 studies	39% ± 7%	Explore
mucus secreting cell	4 studies	49% ± 28%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	29% ± 6%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	44% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	25% ± 7%	Explore
erythrocyte	4 studies	39% ± 16%	Explore
T-helper 17 cell	4 studies	23% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	29% ± 6%	Explore
deuterosomal cell	3 studies	20% ± 2%	Explore
duct epithelial cell	3 studies	41% ± 6%	Explore
ionocyte	3 studies	38% ± 9%	Explore
pancreatic A cell	3 studies	76% ± 9%	Explore
type B pancreatic cell	3 studies	65% ± 12%	Explore
podocyte	3 studies	52% ± 8%	Explore
neural crest cell	3 studies	43% ± 5%	Explore
naive B cell	3 studies	20% ± 6%	Explore
extravillous trophoblast	3 studies	73% ± 13%	Explore
placental villous trophoblast	3 studies	60% ± 25%	Explore
common myeloid progenitor	3 studies	35% ± 10%	Explore
lymphocyte	3 studies	39% ± 8%	Explore
neuroendocrine cell	3 studies	51% ± 12%	Explore
retinal cone cell	3 studies	46% ± 13%	Explore
retinal rod cell	3 studies	29% ± 7%	Explore
microglial cell	3 studies	32% ± 14%	Explore
serous secreting cell	3 studies	51% ± 21%	Explore
intraepithelial lymphocyte	3 studies	27% ± 5%	Explore
Mueller cell	3 studies	31% ± 8%	Explore
acinar cell	3 studies	27% ± 8%	Explore
muscle cell	3 studies	36% ± 24%	Explore
germinal center B cell	3 studies	19% ± 0%	Explore
intermediate monocyte	3 studies	46% ± 10%	Explore
myoepithelial cell	3 studies	45% ± 24%	Explore
luminal cell of prostate epithelium	3 studies	52% ± 6%	Explore
glutamatergic neuron	3 studies	28% ± 7%	Explore
oligodendrocyte precursor cell	3 studies	30% ± 7%	Explore
granulocyte monocyte progenitor cell	3 studies	48% ± 4%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	47% ± 19%	Explore
glial cell	3 studies	38% ± 21%	Explore
hepatocyte	3 studies	46% ± 31%	Explore
group 3 innate lymphoid cell	3 studies	32% ± 14%	Explore
keratinocyte	3 studies	25% ± 6%	Explore
oligodendrocyte	3 studies	25% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	21% ± 4%	Explore
double negative thymocyte	3 studies	27% ± 12%	Explore
progenitor cell of mammary luminal epithelium	3 studies	28% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	39% ± 17%	Explore
peripheral blood	13 studies	24% ± 7%	Explore
intestine	11 studies	39% ± 20%	Explore
kidney	9 studies	37% ± 12%	Explore
eye	8 studies	25% ± 11%	Explore
liver	6 studies	32% ± 23%	Explore
brain	5 studies	27% ± 5%	Explore
uterus	4 studies	50% ± 17%	Explore
breast	4 studies	30% ± 5%	Explore
pancreas	3 studies	60% ± 17%	Explore
placenta	3 studies	56% ± 28%	Explore
bone marrow	3 studies	30% ± 13%	Explore
adrenal gland	3 studies	29% ± 9%	Explore
prostate	3 studies	29% ± 2%	Explore
skin	3 studies	26% ± 4%	Explore
lymph node	3 studies	44% ± 17%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	4708.59	258 / 258	100%	179.51	230 / 230
liver	100%	3065.04	226 / 226	100%	108.37	406 / 406
ovary	100%	2014.13	180 / 180	100%	130.58	430 / 430
pancreas	100%	3961.43	328 / 328	100%	113.41	178 / 178
thymus	100%	4699.49	653 / 653	100%	178.98	605 / 605
brain	100%	3474.75	2640 / 2642	100%	154.34	705 / 705
prostate	100%	4608.73	245 / 245	100%	187.08	501 / 502
kidney	100%	4629.01	89 / 89	100%	144.05	898 / 901
intestine	100%	3431.58	966 / 966	99%	121.04	524 / 527
uterus	99%	2076.92	169 / 170	100%	139.11	459 / 459
stomach	100%	2630.77	359 / 359	99%	102.27	284 / 286
skin	100%	2789.02	1807 / 1809	99%	122.91	469 / 472
breast	100%	2440.10	459 / 459	99%	106.91	1102 / 1118
lung	100%	2683.34	576 / 578	99%	98.81	1142 / 1155
bladder	100%	2178.10	21 / 21	98%	108.33	496 / 504
esophagus	100%	2665.56	1444 / 1445	98%	65.07	180 / 183
adipose	100%	2523.76	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	198.18	80 / 80
heart	100%	5371.60	861 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	169.60	29 / 29
muscle	100%	4670.16	803 / 803	0%	0	0 / 0
spleen	100%	3231.11	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	145.67	45 / 45
ureter	0%	0	0 / 0	100%	48.14	1 / 1
blood vessel	100%	3165.66	1330 / 1335	0%	0	0 / 0
peripheral blood	64%	1309.25	594 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0051350	Biological process	negative regulation of lyase activity
GO_0035971	Biological process	peptidyl-histidine dephosphorylation
GO_0006470	Biological process	protein dephosphorylation
GO_0050860	Biological process	negative regulation of T cell receptor signaling pathway
GO_2000147	Biological process	positive regulation of cell motility
GO_2000984	Biological process	negative regulation of ATP citrate synthase activity
GO_0097581	Biological process	lamellipodium organization
GO_0030036	Biological process	actin cytoskeleton organization
GO_0005886	Cellular component	plasma membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0061851	Cellular component	leading edge of lamellipodium
GO_0016604	Cellular component	nuclear body
GO_0005829	Cellular component	cytosol
GO_0051015	Molecular function	actin filament binding
GO_0044325	Molecular function	transmembrane transporter binding
GO_0019855	Molecular function	calcium channel inhibitor activity
GO_0005515	Molecular function	protein binding
GO_0101006	Molecular function	protein histidine phosphatase activity

Gene name	PHPT1
Protein name	14 kDa phosphohistidine phosphatase (EC 3.9.1.3) (Phosphohistidine phosphatase 1) (PHPT1) (Protein histidine phosphatase) (PHP) (Protein janus-A homolog)
Synonyms	PHP14 HSPC141 CGI-202
Description	FUNCTION: Exhibits phosphohistidine phosphatase activity. .
Accessions	ENST00000371661.5 [Q9NRX4-2] ENST00000247665.12 [Q9NRX4-1] Q9NRX4

PHPT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review