NSA2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	35 studies	43% ± 13%	Explore
natural killer cell	33 studies	32% ± 10%	Explore
CD4-positive, alpha-beta T cell	30 studies	42% ± 16%	Explore
CD8-positive, alpha-beta T cell	30 studies	36% ± 13%	Explore
macrophage	28 studies	31% ± 12%	Explore
fibroblast	27 studies	37% ± 12%	Explore
conventional dendritic cell	27 studies	43% ± 17%	Explore
T cell	25 studies	34% ± 10%	Explore
endothelial cell	25 studies	29% ± 12%	Explore
classical monocyte	23 studies	38% ± 15%	Explore
regulatory T cell	23 studies	43% ± 9%	Explore
smooth muscle cell	21 studies	38% ± 16%	Explore
pericyte	20 studies	36% ± 15%	Explore
memory B cell	20 studies	46% ± 11%	Explore
basal cell	20 studies	30% ± 16%	Explore
non-classical monocyte	20 studies	40% ± 16%	Explore
plasmacytoid dendritic cell	19 studies	38% ± 12%	Explore
naive B cell	19 studies	45% ± 11%	Explore
mast cell	18 studies	37% ± 17%	Explore
dendritic cell	17 studies	39% ± 24%	Explore
monocyte	17 studies	35% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	16 studies	54% ± 17%	Explore
epithelial cell	16 studies	45% ± 22%	Explore
gamma-delta T cell	16 studies	40% ± 14%	Explore
mature NK T cell	15 studies	35% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	53% ± 18%	Explore
connective tissue cell	14 studies	37% ± 13%	Explore
endothelial cell of lymphatic vessel	13 studies	33% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	37% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	37% ± 13%	Explore
plasma cell	12 studies	30% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	45% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	41% ± 13%	Explore
mucosal invariant T cell	11 studies	42% ± 8%	Explore
plasmablast	10 studies	38% ± 18%	Explore
secretory cell	10 studies	38% ± 23%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	44% ± 15%	Explore
myofibroblast cell	10 studies	44% ± 15%	Explore
abnormal cell	10 studies	39% ± 16%	Explore
myeloid cell	10 studies	36% ± 19%	Explore
progenitor cell	8 studies	47% ± 11%	Explore
T follicular helper cell	8 studies	41% ± 8%	Explore
endothelial cell of vascular tree	8 studies	30% ± 17%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	37% ± 13%	Explore
leukocyte	7 studies	41% ± 13%	Explore
capillary endothelial cell	7 studies	23% ± 7%	Explore
goblet cell	7 studies	33% ± 16%	Explore
mesothelial cell	7 studies	48% ± 17%	Explore
vein endothelial cell	7 studies	27% ± 9%	Explore
hematopoietic stem cell	7 studies	66% ± 11%	Explore
precursor B cell	7 studies	47% ± 17%	Explore
ciliated cell	7 studies	44% ± 15%	Explore
immature B cell	7 studies	47% ± 8%	Explore
type II pneumocyte	6 studies	42% ± 14%	Explore
hematopoietic precursor cell	6 studies	52% ± 28%	Explore
club cell	6 studies	32% ± 17%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	42% ± 14%	Explore
epithelial cell of proximal tubule	6 studies	32% ± 11%	Explore
innate lymphoid cell	6 studies	34% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	48% ± 16%	Explore
alveolar macrophage	5 studies	37% ± 11%	Explore
CD4-positive helper T cell	5 studies	29% ± 13%	Explore
endothelial cell of artery	5 studies	24% ± 6%	Explore
enteroendocrine cell	5 studies	34% ± 13%	Explore
intestinal crypt stem cell	5 studies	38% ± 11%	Explore
pro-B cell	5 studies	46% ± 16%	Explore
neuron	5 studies	41% ± 13%	Explore
granulocyte	5 studies	32% ± 9%	Explore
erythrocyte	5 studies	38% ± 18%	Explore
pancreatic A cell	4 studies	44% ± 11%	Explore
type B pancreatic cell	4 studies	46% ± 19%	Explore
mononuclear phagocyte	4 studies	40% ± 13%	Explore
exhausted T cell	4 studies	44% ± 13%	Explore
kidney loop of Henle epithelial cell	4 studies	25% ± 3%	Explore
enterocyte	4 studies	25% ± 6%	Explore
transit amplifying cell	4 studies	35% ± 10%	Explore
erythroblast	4 studies	52% ± 29%	Explore
brush cell	4 studies	34% ± 29%	Explore
microglial cell	4 studies	24% ± 10%	Explore
acinar cell	4 studies	37% ± 19%	Explore
intermediate monocyte	4 studies	45% ± 22%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	38% ± 6%	Explore
glutamatergic neuron	4 studies	39% ± 5%	Explore
hepatocyte	4 studies	37% ± 24%	Explore
T-helper 17 cell	4 studies	31% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	32% ± 11%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	53% ± 16%	Explore
double negative thymocyte	4 studies	58% ± 12%	Explore
oligodendrocyte precursor cell	4 studies	31% ± 12%	Explore
type I pneumocyte	3 studies	47% ± 6%	Explore
deuterosomal cell	3 studies	20% ± 4%	Explore
duct epithelial cell	3 studies	23% ± 2%	Explore
ionocyte	3 studies	34% ± 15%	Explore
precursor cell	3 studies	39% ± 12%	Explore
respiratory goblet cell	3 studies	27% ± 10%	Explore
platelet	3 studies	27% ± 2%	Explore
pancreatic D cell	3 studies	45% ± 13%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	39% ± 9%	Explore
renal alpha-intercalated cell	3 studies	37% ± 5%	Explore
neural crest cell	3 studies	50% ± 10%	Explore
extravillous trophoblast	3 studies	47% ± 15%	Explore
placental villous trophoblast	3 studies	40% ± 9%	Explore
lymphocyte	3 studies	44% ± 13%	Explore
astrocyte	3 studies	22% ± 10%	Explore
retinal cone cell	3 studies	31% ± 2%	Explore
serous secreting cell	3 studies	25% ± 5%	Explore
germinal center B cell	3 studies	41% ± 4%	Explore
myoepithelial cell	3 studies	40% ± 19%	Explore
GABAergic neuron	3 studies	32% ± 5%	Explore
pancreatic ductal cell	3 studies	47% ± 8%	Explore
granulocyte monocyte progenitor cell	3 studies	39% ± 12%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	77% ± 14%	Explore
group 3 innate lymphoid cell	3 studies	49% ± 17%	Explore
T-helper 1 cell	3 studies	39% ± 12%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	61% ± 4%	Explore
double-positive, alpha-beta thymocyte	3 studies	61% ± 2%	Explore
interneuron	3 studies	42% ± 7%	Explore
progenitor cell of mammary luminal epithelium	3 studies	38% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	47% ± 12%	Explore
lung	14 studies	36% ± 14%	Explore
intestine	11 studies	33% ± 16%	Explore
brain	8 studies	26% ± 8%	Explore
kidney	7 studies	33% ± 7%	Explore
lymph node	5 studies	44% ± 6%	Explore
liver	5 studies	38% ± 15%	Explore
pancreas	4 studies	45% ± 14%	Explore
bone marrow	4 studies	42% ± 18%	Explore
eye	4 studies	24% ± 6%	Explore
uterus	4 studies	55% ± 19%	Explore
breast	4 studies	31% ± 6%	Explore
placenta	3 studies	37% ± 10%	Explore
prostate	3 studies	22% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	4804.93	459 / 459	100%	62.57	1118 / 1118
esophagus	100%	4004.67	1445 / 1445	100%	35.39	183 / 183
ovary	100%	8075.73	180 / 180	100%	46.27	430 / 430
pancreas	100%	3231.25	328 / 328	100%	44.70	178 / 178
prostate	100%	4102.56	245 / 245	100%	61.20	502 / 502
uterus	100%	5300.35	170 / 170	100%	54.52	459 / 459
thymus	100%	3343.71	653 / 653	100%	68.92	604 / 605
intestine	100%	4697.49	966 / 966	100%	58.88	526 / 527
bladder	100%	4891.33	21 / 21	100%	48.28	503 / 504
stomach	100%	3724.79	359 / 359	100%	54.54	285 / 286
lung	100%	3129.51	576 / 578	100%	43.03	1154 / 1155
kidney	100%	3535.40	89 / 89	100%	60.11	897 / 901
brain	99%	2369.67	2627 / 2642	100%	43.91	705 / 705
liver	100%	1683.90	225 / 226	100%	38.28	405 / 406
adrenal gland	100%	4058.74	258 / 258	98%	54.71	226 / 230
skin	100%	4086.50	1807 / 1809	98%	50.24	461 / 472
adipose	100%	4707.73	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	80.71	29 / 29
spleen	100%	3309.91	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	48.11	45 / 45
blood vessel	100%	4498.98	1334 / 1335	0%	0	0 / 0
muscle	100%	3665.48	801 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	98%	66.46	78 / 80
heart	95%	2330.79	822 / 861	0%	0	0 / 0
peripheral blood	84%	2684.51	777 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0000460	Biological process	maturation of 5.8S rRNA
GO_0000470	Biological process	maturation of LSU-rRNA
GO_0030687	Cellular component	preribosome, large subunit precursor
GO_0005730	Cellular component	nucleolus
GO_0003723	Molecular function	RNA binding

Gene name	NSA2
Protein name	Ribosome biogenesis protein NSA2 homolog (Hairy cell leukemia protein 1) (TGF-beta-inducible nuclear protein 1) NSA2 ribosome biogenesis factor
Synonyms	TINP1 HUSSY-29
Description	FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity). .
Accessions	ENST00000610426.5 ENST00000515524.1 O95478 A0A0A0MQZ6 ENST00000296802.9 H0YAI9

NSA2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review