NDUFB6 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	26 studies	27% ± 12%	Explore
fibroblast	26 studies	27% ± 13%	Explore
natural killer cell	24 studies	24% ± 9%	Explore
pericyte	22 studies	25% ± 7%	Explore
smooth muscle cell	21 studies	27% ± 10%	Explore
T cell	19 studies	25% ± 8%	Explore
CD8-positive, alpha-beta T cell	19 studies	29% ± 12%	Explore
CD4-positive, alpha-beta T cell	18 studies	27% ± 12%	Explore
macrophage	17 studies	24% ± 10%	Explore
regulatory T cell	17 studies	24% ± 7%	Explore
ciliated cell	16 studies	32% ± 16%	Explore
epithelial cell	15 studies	36% ± 21%	Explore
connective tissue cell	14 studies	28% ± 10%	Explore
plasma cell	13 studies	37% ± 15%	Explore
basal cell	13 studies	30% ± 14%	Explore
myofibroblast cell	13 studies	28% ± 9%	Explore
gamma-delta T cell	13 studies	25% ± 14%	Explore
conventional dendritic cell	12 studies	27% ± 14%	Explore
endothelial cell of lymphatic vessel	12 studies	30% ± 11%	Explore
non-classical monocyte	11 studies	28% ± 10%	Explore
classical monocyte	11 studies	24% ± 7%	Explore
mature NK T cell	11 studies	20% ± 4%	Explore
capillary endothelial cell	11 studies	23% ± 7%	Explore
plasmacytoid dendritic cell	11 studies	30% ± 11%	Explore
B cell	10 studies	22% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	23% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	23% ± 5%	Explore
progenitor cell	10 studies	30% ± 12%	Explore
plasmablast	9 studies	49% ± 23%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	25% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	18% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	23% ± 4%	Explore
endothelial cell of artery	9 studies	22% ± 5%	Explore
vein endothelial cell	9 studies	23% ± 8%	Explore
mucosal invariant T cell	9 studies	20% ± 3%	Explore
endothelial cell of vascular tree	9 studies	24% ± 7%	Explore
neuron	8 studies	37% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	20% ± 3%	Explore
epithelial cell of proximal tubule	7 studies	39% ± 8%	Explore
monocyte	7 studies	20% ± 6%	Explore
enterocyte	7 studies	27% ± 7%	Explore
goblet cell	7 studies	26% ± 13%	Explore
abnormal cell	7 studies	36% ± 17%	Explore
myeloid cell	7 studies	22% ± 10%	Explore
mast cell	7 studies	17% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	27% ± 7%	Explore
club cell	6 studies	26% ± 11%	Explore
secretory cell	6 studies	28% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	32% ± 14%	Explore
naive B cell	6 studies	18% ± 4%	Explore
kidney loop of Henle epithelial cell	6 studies	42% ± 11%	Explore
renal alpha-intercalated cell	6 studies	46% ± 14%	Explore
type I pneumocyte	6 studies	30% ± 11%	Explore
astrocyte	6 studies	30% ± 12%	Explore
dendritic cell	6 studies	31% ± 17%	Explore
T follicular helper cell	6 studies	19% ± 2%	Explore
memory B cell	6 studies	22% ± 7%	Explore
ionocyte	5 studies	31% ± 9%	Explore
erythroblast	5 studies	47% ± 17%	Explore
mesothelial cell	5 studies	35% ± 14%	Explore
type II pneumocyte	5 studies	36% ± 16%	Explore
erythrocyte	5 studies	42% ± 17%	Explore
oligodendrocyte	5 studies	24% ± 5%	Explore
innate lymphoid cell	5 studies	20% ± 2%	Explore
glutamatergic neuron	5 studies	34% ± 16%	Explore
oligodendrocyte precursor cell	5 studies	30% ± 11%	Explore
hematopoietic precursor cell	4 studies	35% ± 15%	Explore
pancreatic A cell	4 studies	57% ± 13%	Explore
exhausted T cell	4 studies	29% ± 8%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	43% ± 7%	Explore
retinal ganglion cell	4 studies	59% ± 27%	Explore
hematopoietic stem cell	4 studies	26% ± 8%	Explore
amacrine cell	4 studies	36% ± 17%	Explore
retinal rod cell	4 studies	31% ± 15%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	30% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	27% ± 8%	Explore
transit amplifying cell	4 studies	23% ± 2%	Explore
interneuron	4 studies	26% ± 15%	Explore
duct epithelial cell	3 studies	21% ± 8%	Explore
precursor cell	3 studies	44% ± 8%	Explore
type B pancreatic cell	3 studies	61% ± 7%	Explore
intestinal crypt stem cell	3 studies	28% ± 12%	Explore
neural crest cell	3 studies	32% ± 6%	Explore
lymphocyte	3 studies	30% ± 8%	Explore
precursor B cell	3 studies	23% ± 7%	Explore
pro-B cell	3 studies	20% ± 2%	Explore
retina horizontal cell	3 studies	36% ± 16%	Explore
retinal cone cell	3 studies	54% ± 19%	Explore
alveolar macrophage	3 studies	24% ± 1%	Explore
serous secreting cell	3 studies	27% ± 8%	Explore
Mueller cell	3 studies	31% ± 8%	Explore
cardiac muscle cell	3 studies	27% ± 10%	Explore
muscle cell	3 studies	33% ± 19%	Explore
germinal center B cell	3 studies	23% ± 4%	Explore
intermediate monocyte	3 studies	31% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	29% ± 7%	Explore
GABAergic neuron	3 studies	35% ± 11%	Explore
pancreatic ductal cell	3 studies	53% ± 14%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	51% ± 27%	Explore
enteroendocrine cell	3 studies	42% ± 13%	Explore
glial cell	3 studies	31% ± 17%	Explore
group 3 innate lymphoid cell	3 studies	29% ± 14%	Explore
T-helper 1 cell	3 studies	26% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	21% ± 3%	Explore
double negative thymocyte	3 studies	35% ± 21%	Explore
hepatocyte	3 studies	40% ± 22%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	14 studies	28% ± 11%	Explore
peripheral blood	11 studies	24% ± 4%	Explore
intestine	9 studies	24% ± 10%	Explore
brain	9 studies	26% ± 8%	Explore
kidney	8 studies	30% ± 5%	Explore
eye	6 studies	32% ± 13%	Explore
pancreas	5 studies	43% ± 21%	Explore
liver	5 studies	33% ± 22%	Explore
lymph node	5 studies	24% ± 7%	Explore
bone marrow	4 studies	21% ± 5%	Explore
uterus	4 studies	27% ± 13%	Explore
adrenal gland	3 studies	26% ± 3%	Explore
esophagus	3 studies	34% ± 22%	Explore
thymus	3 studies	44% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1607.15	1445 / 1445	100%	64.09	183 / 183
kidney	100%	2440.19	89 / 89	100%	86.10	901 / 901
ovary	100%	1196.78	180 / 180	100%	99.13	430 / 430
stomach	100%	1444.09	359 / 359	100%	84.92	286 / 286
uterus	100%	1490.96	170 / 170	100%	107.05	459 / 459
brain	100%	2319.93	2641 / 2642	100%	114.85	705 / 705
adrenal gland	100%	2058.75	258 / 258	100%	112.29	229 / 230
liver	100%	1485.34	225 / 226	100%	92.91	406 / 406
thymus	100%	1549.40	651 / 653	100%	92.89	604 / 605
breast	100%	1591.12	459 / 459	99%	91.33	1111 / 1118
intestine	100%	1688.59	966 / 966	99%	87.24	523 / 527
bladder	100%	1487.90	21 / 21	99%	84.34	500 / 504
lung	99%	1338.27	573 / 578	100%	78.51	1155 / 1155
skin	100%	1496.00	1801 / 1809	99%	70.88	469 / 472
prostate	100%	1315.00	244 / 245	99%	92.00	498 / 502
pancreas	97%	720.50	319 / 328	100%	69.58	178 / 178
adipose	100%	1553.83	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	71.96	80 / 80
lymph node	0%	0	0 / 0	100%	96.00	29 / 29
muscle	100%	2463.84	803 / 803	0%	0	0 / 0
spleen	100%	1228.54	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	108.29	45 / 45
ureter	0%	0	0 / 0	100%	54.72	1 / 1
blood vessel	100%	1716.07	1332 / 1335	0%	0	0 / 0
heart	99%	3489.53	850 / 861	0%	0	0 / 0
peripheral blood	88%	1204.47	815 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0042775	Biological process	mitochondrial ATP synthesis coupled electron transport
GO_0009060	Biological process	aerobic respiration
GO_0006120	Biological process	mitochondrial electron transport, NADH to ubiquinone
GO_0042776	Biological process	proton motive force-driven mitochondrial ATP synthesis
GO_0055085	Biological process	transmembrane transport
GO_0032981	Biological process	mitochondrial respiratory chain complex I assembly
GO_0031966	Cellular component	mitochondrial membrane
GO_0045271	Cellular component	respiratory chain complex I
GO_0005654	Cellular component	nucleoplasm
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005739	Cellular component	mitochondrion
GO_0008137	Molecular function	NADH dehydrogenase (ubiquinone) activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	NDUFB6
Protein name	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (Complex I-B17) (CI-B17) (NADH-ubiquinone oxidoreductase B17 subunit) NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (Complex I-B17) (NADH-ubiquinone oxidoreductase B17 subunit)
Synonyms
Description	FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. .
Accessions	A0A087WZX2 ENST00000350021.2 [O95139-2] ENST00000366466.5 O95139 ENST00000379847.8 [O95139-1]

NDUFB6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review