MICOS10 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	33 studies	37% ± 15%	Explore
macrophage	29 studies	43% ± 16%	Explore
natural killer cell	27 studies	27% ± 9%	Explore
endothelial cell	26 studies	35% ± 16%	Explore
CD4-positive, alpha-beta T cell	26 studies	34% ± 13%	Explore
CD8-positive, alpha-beta T cell	26 studies	28% ± 9%	Explore
B cell	25 studies	28% ± 11%	Explore
smooth muscle cell	25 studies	39% ± 13%	Explore
pericyte	25 studies	42% ± 16%	Explore
classical monocyte	23 studies	36% ± 14%	Explore
conventional dendritic cell	23 studies	41% ± 14%	Explore
T cell	22 studies	32% ± 13%	Explore
non-classical monocyte	21 studies	44% ± 15%	Explore
regulatory T cell	19 studies	31% ± 11%	Explore
epithelial cell	18 studies	43% ± 23%	Explore
connective tissue cell	17 studies	37% ± 16%	Explore
monocyte	16 studies	39% ± 17%	Explore
basal cell	16 studies	39% ± 18%	Explore
mast cell	15 studies	32% ± 8%	Explore
endothelial cell of lymphatic vessel	15 studies	39% ± 14%	Explore
ciliated cell	14 studies	55% ± 16%	Explore
gamma-delta T cell	14 studies	28% ± 15%	Explore
myofibroblast cell	13 studies	43% ± 16%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	27% ± 8%	Explore
dendritic cell	11 studies	45% ± 26%	Explore
memory B cell	11 studies	26% ± 6%	Explore
plasma cell	11 studies	35% ± 16%	Explore
mature NK T cell	11 studies	28% ± 8%	Explore
secretory cell	10 studies	35% ± 17%	Explore
capillary endothelial cell	10 studies	25% ± 8%	Explore
goblet cell	10 studies	39% ± 21%	Explore
vein endothelial cell	10 studies	26% ± 10%	Explore
endothelial cell of vascular tree	10 studies	29% ± 9%	Explore
myeloid cell	10 studies	36% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	27% ± 7%	Explore
naive B cell	9 studies	25% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	27% ± 6%	Explore
progenitor cell	9 studies	51% ± 21%	Explore
plasmacytoid dendritic cell	9 studies	30% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	27% ± 12%	Explore
endothelial cell of artery	8 studies	33% ± 13%	Explore
microglial cell	8 studies	37% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	26% ± 11%	Explore
leukocyte	7 studies	36% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	23% ± 6%	Explore
enterocyte	7 studies	42% ± 15%	Explore
T follicular helper cell	7 studies	35% ± 10%	Explore
type I pneumocyte	6 studies	30% ± 17%	Explore
plasmablast	6 studies	43% ± 21%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	28% ± 9%	Explore
club cell	6 studies	28% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	26% ± 6%	Explore
epithelial cell of proximal tubule	6 studies	50% ± 10%	Explore
kidney loop of Henle epithelial cell	6 studies	52% ± 16%	Explore
renal alpha-intercalated cell	6 studies	75% ± 12%	Explore
abnormal cell	6 studies	37% ± 13%	Explore
transit amplifying cell	6 studies	52% ± 28%	Explore
mucosal invariant T cell	6 studies	25% ± 4%	Explore
alveolar macrophage	5 studies	42% ± 11%	Explore
hematopoietic precursor cell	5 studies	34% ± 17%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	32% ± 12%	Explore
mononuclear phagocyte	5 studies	52% ± 15%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	63% ± 9%	Explore
intestinal crypt stem cell	5 studies	49% ± 22%	Explore
precursor B cell	5 studies	28% ± 10%	Explore
innate lymphoid cell	5 studies	27% ± 6%	Explore
type II pneumocyte	5 studies	39% ± 23%	Explore
CD4-positive helper T cell	4 studies	25% ± 9%	Explore
ionocyte	4 studies	35% ± 7%	Explore
enteroendocrine cell	4 studies	53% ± 14%	Explore
mesothelial cell	4 studies	39% ± 21%	Explore
retinal ganglion cell	4 studies	65% ± 29%	Explore
brush cell	4 studies	27% ± 11%	Explore
retina horizontal cell	4 studies	41% ± 18%	Explore
adventitial cell	4 studies	30% ± 10%	Explore
intermediate monocyte	4 studies	58% ± 16%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	39% ± 15%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	43% ± 18%	Explore
T-helper 17 cell	4 studies	32% ± 10%	Explore
deuterosomal cell	3 studies	55% ± 4%	Explore
duct epithelial cell	3 studies	30% ± 2%	Explore
respiratory goblet cell	3 studies	28% ± 8%	Explore
pancreatic A cell	3 studies	70% ± 14%	Explore
type B pancreatic cell	3 studies	55% ± 18%	Explore
kidney connecting tubule epithelial cell	3 studies	76% ± 9%	Explore
podocyte	3 studies	42% ± 7%	Explore
renal beta-intercalated cell	3 studies	72% ± 20%	Explore
neural crest cell	3 studies	36% ± 5%	Explore
retinal bipolar neuron	3 studies	34% ± 18%	Explore
renal principal cell	3 studies	72% ± 4%	Explore
erythroblast	3 studies	52% ± 18%	Explore
lymphocyte	3 studies	45% ± 16%	Explore
astrocyte	3 studies	36% ± 12%	Explore
retinal cone cell	3 studies	57% ± 18%	Explore
retinal pigment epithelial cell	3 studies	38% ± 29%	Explore
retinal rod cell	3 studies	31% ± 15%	Explore
serous secreting cell	3 studies	44% ± 15%	Explore
intraepithelial lymphocyte	3 studies	33% ± 7%	Explore
germinal center B cell	3 studies	39% ± 5%	Explore
exhausted T cell	3 studies	20% ± 3%	Explore
neuron	3 studies	48% ± 19%	Explore
granulocyte	3 studies	34% ± 14%	Explore
luminal cell of prostate epithelium	3 studies	44% ± 6%	Explore
muscle cell	3 studies	38% ± 28%	Explore
granulocyte monocyte progenitor cell	3 studies	38% ± 17%	Explore
glial cell	3 studies	37% ± 19%	Explore
erythrocyte	3 studies	51% ± 24%	Explore
group 3 innate lymphoid cell	3 studies	32% ± 14%	Explore
keratinocyte	3 studies	38% ± 7%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	22% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	21% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	14 studies	38% ± 17%	Explore
peripheral blood	13 studies	33% ± 11%	Explore
intestine	12 studies	37% ± 18%	Explore
kidney	8 studies	39% ± 13%	Explore
eye	8 studies	28% ± 13%	Explore
uterus	5 studies	46% ± 16%	Explore
liver	4 studies	38% ± 23%	Explore
prostate	4 studies	24% ± 4%	Explore
lymph node	4 studies	27% ± 4%	Explore
breast	4 studies	30% ± 11%	Explore
brain	4 studies	36% ± 12%	Explore
pancreas	3 studies	59% ± 19%	Explore
bone marrow	3 studies	26% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4635.85	1445 / 1445	100%	5.98	183 / 183
ovary	100%	2275.81	180 / 180	100%	6.39	430 / 430
prostate	100%	4496.03	245 / 245	100%	6.81	502 / 502
stomach	100%	3096.22	359 / 359	100%	6.09	286 / 286
brain	100%	4208.63	2640 / 2642	100%	5.70	705 / 705
thymus	100%	2837.30	653 / 653	100%	5.94	604 / 605
breast	100%	2911.35	459 / 459	100%	5.85	1116 / 1118
intestine	100%	4698.18	966 / 966	100%	5.91	526 / 527
bladder	100%	4041.14	21 / 21	100%	4.70	503 / 504
uterus	100%	3073.46	170 / 170	100%	4.29	458 / 459
kidney	100%	4448.62	89 / 89	100%	6.49	899 / 901
lung	100%	2741.43	576 / 578	100%	3.87	1150 / 1155
pancreas	98%	1361.23	322 / 328	100%	4.69	178 / 178
skin	100%	2819.58	1807 / 1809	98%	3.85	463 / 472
adrenal gland	100%	3242.28	258 / 258	94%	4.94	216 / 230
liver	99%	1455.38	224 / 226	76%	1.59	307 / 406
adipose	100%	2892.05	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3494.02	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	2.99	29 / 29
spleen	100%	2280.02	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	3.87	45 / 45
ureter	0%	0	0 / 0	100%	4.38	1 / 1
muscle	100%	3404.71	802 / 803	0%	0	0 / 0
heart	100%	5558.70	857 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	98%	4.22	78 / 80
peripheral blood	72%	1323.45	671 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	MICOS10
Protein name	MICOS complex subunit MIC10 (Mitochondrial inner membrane organizing system protein 1) MICOS complex subunit MIC10
Synonyms	MIC10 C1orf151 MINOS1
Description	FUNCTION: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. . FUNCTION: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. . FUNCTION: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. .
Accessions	ENST00000322753.7 [Q5TGZ0-1] A0A087WU07 ENST00000617872.4 A0A3B3IRY5 ENST00000648702.1 Q5TGZ0

GO_0007007	Biological process	inner mitochondrial membrane organization
GO_0042407	Biological process	cristae formation
GO_0008150	Biological process	biological_process
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0061617	Cellular component	MICOS complex
GO_0044284	Cellular component	mitochondrial crista junction
GO_0001401	Cellular component	SAM complex
GO_0005739	Cellular component	mitochondrion
GO_0140275	Cellular component	MIB complex
GO_0005515	Molecular function	protein binding
GO_0003674	Molecular function	molecular_function

MICOS10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review