GTF3C6 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	24 studies	26% ± 11%	Explore
natural killer cell	24 studies	23% ± 9%	Explore
regulatory T cell	19 studies	29% ± 10%	Explore
CD8-positive, alpha-beta T cell	18 studies	29% ± 11%	Explore
B cell	17 studies	21% ± 6%	Explore
endothelial cell	17 studies	25% ± 10%	Explore
classical monocyte	16 studies	25% ± 11%	Explore
conventional dendritic cell	15 studies	28% ± 15%	Explore
T cell	14 studies	28% ± 9%	Explore
non-classical monocyte	14 studies	29% ± 13%	Explore
CD4-positive, alpha-beta T cell	14 studies	29% ± 13%	Explore
fibroblast	14 studies	24% ± 11%	Explore
epithelial cell	14 studies	36% ± 22%	Explore
ciliated cell	11 studies	34% ± 16%	Explore
pericyte	11 studies	22% ± 5%	Explore
smooth muscle cell	11 studies	25% ± 5%	Explore
memory B cell	10 studies	21% ± 6%	Explore
gamma-delta T cell	10 studies	25% ± 17%	Explore
monocyte	9 studies	22% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	21% ± 4%	Explore
mature NK T cell	9 studies	20% ± 2%	Explore
connective tissue cell	9 studies	23% ± 6%	Explore
mucosal invariant T cell	9 studies	18% ± 2%	Explore
plasmacytoid dendritic cell	9 studies	28% ± 10%	Explore
basal cell	8 studies	29% ± 17%	Explore
platelet	8 studies	25% ± 8%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	22% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	23% ± 3%	Explore
abnormal cell	8 studies	31% ± 15%	Explore
myeloid cell	8 studies	30% ± 14%	Explore
plasma cell	7 studies	35% ± 15%	Explore
plasmablast	7 studies	45% ± 21%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	26% ± 12%	Explore
secretory cell	7 studies	26% ± 14%	Explore
epithelial cell of proximal tubule	7 studies	29% ± 6%	Explore
myofibroblast cell	7 studies	24% ± 3%	Explore
progenitor cell	7 studies	22% ± 4%	Explore
endothelial cell of artery	7 studies	19% ± 4%	Explore
dendritic cell	7 studies	35% ± 22%	Explore
endothelial cell of lymphatic vessel	7 studies	25% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	27% ± 11%	Explore
club cell	6 studies	27% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	25% ± 4%	Explore
kidney loop of Henle epithelial cell	6 studies	26% ± 5%	Explore
innate lymphoid cell	6 studies	19% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	36% ± 11%	Explore
naive B cell	5 studies	22% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	20% ± 2%	Explore
enteroendocrine cell	5 studies	32% ± 15%	Explore
erythroblast	5 studies	36% ± 15%	Explore
hematopoietic stem cell	5 studies	25% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	30% ± 13%	Explore
endothelial cell of vascular tree	5 studies	20% ± 3%	Explore
alveolar macrophage	4 studies	18% ± 2%	Explore
hematopoietic precursor cell	4 studies	39% ± 19%	Explore
respiratory goblet cell	4 studies	34% ± 26%	Explore
pancreatic A cell	4 studies	49% ± 20%	Explore
leukocyte	4 studies	27% ± 10%	Explore
mononuclear phagocyte	4 studies	27% ± 12%	Explore
exhausted T cell	4 studies	33% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	32% ± 5%	Explore
vein endothelial cell	4 studies	17% ± 2%	Explore
megakaryocyte	4 studies	32% ± 13%	Explore
capillary endothelial cell	4 studies	19% ± 3%	Explore
precursor B cell	4 studies	29% ± 7%	Explore
neuron	4 studies	34% ± 16%	Explore
T follicular helper cell	4 studies	20% ± 3%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	38% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	26% ± 6%	Explore
oligodendrocyte precursor cell	4 studies	28% ± 10%	Explore
mast cell	4 studies	21% ± 4%	Explore
goblet cell	4 studies	27% ± 10%	Explore
duct epithelial cell	3 studies	19% ± 5%	Explore
type B pancreatic cell	3 studies	46% ± 11%	Explore
enterocyte	3 studies	20% ± 4%	Explore
neural crest cell	3 studies	26% ± 6%	Explore
common myeloid progenitor	3 studies	32% ± 17%	Explore
neuroendocrine cell	3 studies	34% ± 10%	Explore
immature B cell	3 studies	21% ± 6%	Explore
type II pneumocyte	3 studies	36% ± 19%	Explore
astrocyte	3 studies	27% ± 14%	Explore
erythrocyte	3 studies	41% ± 17%	Explore
germinal center B cell	3 studies	21% ± 4%	Explore
intermediate monocyte	3 studies	39% ± 16%	Explore
luminal cell of prostate epithelium	3 studies	28% ± 6%	Explore
pancreatic ductal cell	3 studies	46% ± 11%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	44% ± 23%	Explore
intestinal crypt stem cell	3 studies	24% ± 9%	Explore
transit amplifying cell	3 studies	17% ± 1%	Explore
T-helper 17 cell	3 studies	32% ± 19%	Explore
T-helper 1 cell	3 studies	30% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	20% ± 5%	Explore
double negative thymocyte	3 studies	36% ± 20%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	12 studies	25% ± 8%	Explore
lung	11 studies	28% ± 12%	Explore
kidney	8 studies	23% ± 3%	Explore
intestine	8 studies	22% ± 10%	Explore
liver	6 studies	26% ± 17%	Explore
pancreas	4 studies	43% ± 19%	Explore
bone marrow	4 studies	21% ± 2%	Explore
uterus	3 studies	28% ± 14%	Explore
adrenal gland	3 studies	18% ± 3%	Explore
thymus	3 studies	41% ± 19%	Explore
lymph node	3 studies	23% ± 5%	Explore
breast	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	1155.95	180 / 180	100%	110.42	430 / 430
prostate	100%	2566.66	245 / 245	100%	358.09	502 / 502
uterus	100%	1235.25	170 / 170	100%	197.39	459 / 459
esophagus	100%	1777.96	1444 / 1445	100%	110.58	183 / 183
brain	100%	1861.56	2640 / 2642	100%	202.13	705 / 705
breast	100%	1538.45	459 / 459	100%	175.17	1116 / 1118
thymus	100%	1413.41	652 / 653	100%	146.59	604 / 605
kidney	100%	2565.04	89 / 89	99%	161.10	896 / 901
bladder	100%	1653.76	21 / 21	99%	150.23	501 / 504
skin	99%	1512.18	1798 / 1809	100%	165.01	471 / 472
adrenal gland	100%	2441.45	258 / 258	99%	120.13	228 / 230
stomach	100%	1520.85	359 / 359	99%	128.62	283 / 286
intestine	100%	1896.30	966 / 966	99%	137.20	520 / 527
lung	98%	1315.14	566 / 578	100%	138.83	1153 / 1155
liver	99%	1009.32	223 / 226	99%	111.39	400 / 406
pancreas	98%	879.22	320 / 328	99%	128.23	177 / 178
lymph node	0%	0	0 / 0	100%	207.26	29 / 29
muscle	100%	3851.17	803 / 803	0%	0	0 / 0
spleen	100%	1571.78	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	149.93	45 / 45
ureter	0%	0	0 / 0	100%	92.49	1 / 1
adipose	100%	1555.49	1203 / 1204	0%	0	0 / 0
blood vessel	100%	1507.97	1329 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	154.17	79 / 80
heart	98%	2334.16	845 / 861	0%	0	0 / 0
peripheral blood	82%	1056.49	764 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0042797	Biological process	tRNA transcription by RNA polymerase III
GO_0042791	Biological process	5S class rRNA transcription by RNA polymerase III
GO_0006383	Biological process	transcription by RNA polymerase III
GO_0000127	Cellular component	transcription factor TFIIIC complex
GO_0016604	Cellular component	nuclear body
GO_0005654	Cellular component	nucleoplasm
GO_0003677	Molecular function	DNA binding
GO_0000995	Molecular function	RNA polymerase III general transcription initiation factor activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	GTF3C6
Protein name	GTF3C6 protein General transcription factor 3C polypeptide 6 (Transcription factor IIIC 35 kDa subunit) (TFIIIC 35 kDa subunit) (TFIIIC35) (Transcription factor IIIC subunit 6)
Synonyms	NPD020 CDA020 C6orf51
Description	FUNCTION: Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters. .
Accessions	ENST00000329970.8 Q969F1 Q3SWV5

GTF3C6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review