GTF2A2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	29 studies	26% ± 9%	Explore
fibroblast	26 studies	27% ± 11%	Explore
endothelial cell	25 studies	30% ± 12%	Explore
B cell	24 studies	26% ± 9%	Explore
CD4-positive, alpha-beta T cell	24 studies	28% ± 14%	Explore
conventional dendritic cell	23 studies	28% ± 15%	Explore
CD8-positive, alpha-beta T cell	23 studies	28% ± 12%	Explore
smooth muscle cell	21 studies	27% ± 8%	Explore
pericyte	20 studies	26% ± 6%	Explore
regulatory T cell	20 studies	29% ± 9%	Explore
classical monocyte	19 studies	26% ± 11%	Explore
macrophage	18 studies	24% ± 10%	Explore
T cell	17 studies	25% ± 8%	Explore
plasmacytoid dendritic cell	17 studies	33% ± 12%	Explore
epithelial cell	16 studies	34% ± 19%	Explore
non-classical monocyte	15 studies	29% ± 13%	Explore
mast cell	14 studies	21% ± 5%	Explore
ciliated cell	14 studies	37% ± 15%	Explore
naive B cell	14 studies	22% ± 4%	Explore
basal cell	13 studies	32% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	23% ± 5%	Explore
connective tissue cell	13 studies	27% ± 8%	Explore
monocyte	13 studies	24% ± 9%	Explore
gamma-delta T cell	13 studies	28% ± 14%	Explore
endothelial cell of lymphatic vessel	12 studies	26% ± 8%	Explore
plasma cell	12 studies	32% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	27% ± 6%	Explore
mature NK T cell	12 studies	24% ± 4%	Explore
memory B cell	12 studies	24% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	26% ± 10%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	27% ± 4%	Explore
capillary endothelial cell	11 studies	22% ± 4%	Explore
secretory cell	10 studies	28% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	26% ± 4%	Explore
abnormal cell	10 studies	28% ± 11%	Explore
endothelial cell of artery	10 studies	23% ± 5%	Explore
vein endothelial cell	10 studies	20% ± 4%	Explore
endothelial cell of vascular tree	10 studies	25% ± 6%	Explore
myofibroblast cell	9 studies	30% ± 6%	Explore
dendritic cell	9 studies	41% ± 27%	Explore
mucosal invariant T cell	9 studies	25% ± 3%	Explore
plasmablast	8 studies	42% ± 21%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	30% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	27% ± 10%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	35% ± 10%	Explore
kidney loop of Henle epithelial cell	6 studies	22% ± 3%	Explore
innate lymphoid cell	6 studies	21% ± 4%	Explore
myeloid cell	6 studies	30% ± 13%	Explore
neuron	6 studies	39% ± 17%	Explore
erythrocyte	6 studies	33% ± 20%	Explore
T follicular helper cell	6 studies	25% ± 2%	Explore
hematopoietic precursor cell	5 studies	36% ± 19%	Explore
leukocyte	5 studies	25% ± 8%	Explore
mesothelial cell	5 studies	32% ± 15%	Explore
transit amplifying cell	5 studies	19% ± 2%	Explore
erythroblast	5 studies	40% ± 20%	Explore
precursor B cell	5 studies	35% ± 11%	Explore
pro-B cell	5 studies	31% ± 6%	Explore
type II pneumocyte	5 studies	29% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	33% ± 14%	Explore
club cell	4 studies	32% ± 9%	Explore
deuterosomal cell	4 studies	37% ± 12%	Explore
pancreatic A cell	4 studies	51% ± 8%	Explore
exhausted T cell	4 studies	36% ± 6%	Explore
progenitor cell	4 studies	25% ± 4%	Explore
epithelial cell of proximal tubule	4 studies	18% ± 1%	Explore
renal alpha-intercalated cell	4 studies	34% ± 4%	Explore
hematopoietic stem cell	4 studies	30% ± 12%	Explore
megakaryocyte	4 studies	30% ± 8%	Explore
platelet	4 studies	24% ± 6%	Explore
type I pneumocyte	4 studies	29% ± 11%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	38% ± 4%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	29% ± 4%	Explore
oligodendrocyte precursor cell	4 studies	23% ± 5%	Explore
goblet cell	4 studies	27% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	24% ± 5%	Explore
pancreatic D cell	3 studies	49% ± 20%	Explore
type B pancreatic cell	3 studies	55% ± 3%	Explore
mononuclear phagocyte	3 studies	32% ± 12%	Explore
glomerular endothelial cell	3 studies	24% ± 2%	Explore
podocyte	3 studies	49% ± 6%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	28% ± 4%	Explore
neural crest cell	3 studies	29% ± 6%	Explore
lymphocyte	3 studies	34% ± 10%	Explore
immature B cell	3 studies	27% ± 7%	Explore
amacrine cell	3 studies	39% ± 14%	Explore
retina horizontal cell	3 studies	33% ± 17%	Explore
retinal cone cell	3 studies	61% ± 15%	Explore
retinal rod cell	3 studies	30% ± 9%	Explore
alveolar macrophage	3 studies	20% ± 0%	Explore
Mueller cell	3 studies	36% ± 11%	Explore
germinal center B cell	3 studies	27% ± 4%	Explore
intermediate monocyte	3 studies	42% ± 17%	Explore
GABAergic neuron	3 studies	30% ± 9%	Explore
glutamatergic neuron	3 studies	34% ± 12%	Explore
pancreatic ductal cell	3 studies	52% ± 7%	Explore
granulocyte	3 studies	23% ± 6%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	47% ± 29%	Explore
enteroendocrine cell	3 studies	37% ± 17%	Explore
group 3 innate lymphoid cell	3 studies	29% ± 15%	Explore
T-helper 17 cell	3 studies	37% ± 22%	Explore
T-helper 1 cell	3 studies	32% ± 11%	Explore
double negative thymocyte	3 studies	41% ± 17%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	14 studies	29% ± 12%	Explore
peripheral blood	14 studies	30% ± 9%	Explore
kidney	8 studies	23% ± 4%	Explore
intestine	7 studies	25% ± 11%	Explore
eye	6 studies	27% ± 13%	Explore
brain	6 studies	23% ± 8%	Explore
bone marrow	5 studies	20% ± 3%	Explore
liver	5 studies	31% ± 23%	Explore
lymph node	5 studies	24% ± 5%	Explore
pancreas	4 studies	47% ± 13%	Explore
uterus	4 studies	31% ± 14%	Explore
breast	4 studies	23% ± 1%	Explore
thymus	3 studies	40% ± 17%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	1506.73	2642 / 2642	100%	44.06	705 / 705
esophagus	100%	1736.16	1445 / 1445	100%	36.54	183 / 183
liver	100%	815.39	226 / 226	100%	24.70	406 / 406
lung	100%	1450.48	578 / 578	100%	43.59	1155 / 1155
ovary	100%	1701.01	180 / 180	100%	46.48	430 / 430
uterus	100%	1679.16	170 / 170	100%	50.22	459 / 459
skin	100%	1531.17	1807 / 1809	100%	43.44	472 / 472
thymus	100%	1587.05	653 / 653	100%	39.73	604 / 605
prostate	100%	1789.73	245 / 245	100%	45.54	501 / 502
breast	100%	1711.95	459 / 459	100%	40.69	1115 / 1118
stomach	100%	1307.12	359 / 359	100%	42.94	285 / 286
bladder	100%	1740.10	21 / 21	100%	41.98	502 / 504
adrenal gland	100%	1789.07	258 / 258	100%	46.88	229 / 230
kidney	100%	1952.62	89 / 89	100%	26.70	897 / 901
intestine	100%	1879.01	966 / 966	99%	41.03	522 / 527
pancreas	98%	696.30	322 / 328	99%	36.11	177 / 178
adipose	100%	1711.63	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	49.37	29 / 29
muscle	100%	1584.19	803 / 803	0%	0	0 / 0
spleen	100%	1553.37	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	40.62	45 / 45
ureter	0%	0	0 / 0	100%	30.79	1 / 1
blood vessel	100%	1841.09	1334 / 1335	0%	0	0 / 0
heart	99%	1582.74	853 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	98%	26.12	78 / 80
peripheral blood	97%	1392.30	899 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0051123	Biological process	RNA polymerase II preinitiation complex assembly
GO_0006366	Biological process	transcription by RNA polymerase II
GO_0060261	Biological process	positive regulation of transcription initiation by RNA polymerase II
GO_0006367	Biological process	transcription initiation at RNA polymerase II promoter
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0030054	Cellular component	cell junction
GO_0005669	Cellular component	transcription factor TFIID complex
GO_0005654	Cellular component	nucleoplasm
GO_0005672	Cellular component	transcription factor TFIIA complex
GO_0005634	Cellular component	nucleus
GO_0061629	Molecular function	RNA polymerase II-specific DNA-binding transcription factor binding
GO_0046982	Molecular function	protein heterodimerization activity
GO_0042803	Molecular function	protein homodimerization activity
GO_0017025	Molecular function	TBP-class protein binding
GO_0016251	Molecular function	RNA polymerase II general transcription initiation factor activity
GO_0001091	Molecular function	RNA polymerase II general transcription initiation factor binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	GTF2A2
Protein name	Transcription initiation factor IIA gamma chain Transcription initiation factor IIA subunit 2 (General transcription factor IIA subunit 2) (TFIIA p12 subunit) (TFIIA-12) (TFIIAS) (Transcription initiation factor IIA gamma chain) (TFIIA-gamma)
Synonyms	TF2A2
Description	FUNCTION: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. .
Accessions	ENST00000396061.5 ENST00000559706.1 A0A0B4J1Z5 ENST00000396063.5 ENST00000484743.5 ENST00000396060.7 A8MYR4 P52657 H0YK39 ENST00000396064.7

GTF2A2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review