GADD45GIP1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	31 studies	27% ± 9%	Explore
fibroblast	31 studies	34% ± 14%	Explore
natural killer cell	30 studies	26% ± 8%	Explore
endothelial cell	28 studies	39% ± 16%	Explore
CD4-positive, alpha-beta T cell	28 studies	28% ± 10%	Explore
CD8-positive, alpha-beta T cell	28 studies	29% ± 11%	Explore
macrophage	25 studies	30% ± 12%	Explore
pericyte	25 studies	38% ± 14%	Explore
T cell	23 studies	27% ± 10%	Explore
smooth muscle cell	23 studies	37% ± 12%	Explore
conventional dendritic cell	21 studies	30% ± 14%	Explore
regulatory T cell	19 studies	28% ± 9%	Explore
epithelial cell	18 studies	42% ± 20%	Explore
classical monocyte	18 studies	28% ± 9%	Explore
memory B cell	17 studies	25% ± 6%	Explore
basal cell	17 studies	34% ± 15%	Explore
connective tissue cell	17 studies	37% ± 15%	Explore
endothelial cell of lymphatic vessel	16 studies	48% ± 13%	Explore
ciliated cell	16 studies	50% ± 18%	Explore
non-classical monocyte	16 studies	26% ± 11%	Explore
monocyte	15 studies	26% ± 9%	Explore
naive B cell	15 studies	23% ± 6%	Explore
mast cell	14 studies	27% ± 7%	Explore
gamma-delta T cell	14 studies	29% ± 14%	Explore
myofibroblast cell	13 studies	38% ± 12%	Explore
dendritic cell	12 studies	36% ± 24%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	26% ± 5%	Explore
mature NK T cell	12 studies	25% ± 6%	Explore
capillary endothelial cell	12 studies	31% ± 11%	Explore
plasma cell	11 studies	43% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	25% ± 6%	Explore
vein endothelial cell	11 studies	34% ± 11%	Explore
myeloid cell	11 studies	30% ± 14%	Explore
secretory cell	10 studies	27% ± 10%	Explore
plasmacytoid dendritic cell	10 studies	28% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	30% ± 9%	Explore
endothelial cell of artery	10 studies	30% ± 10%	Explore
endothelial cell of vascular tree	10 studies	36% ± 7%	Explore
plasmablast	9 studies	49% ± 24%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	30% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	26% ± 5%	Explore
abnormal cell	9 studies	43% ± 17%	Explore
mucosal invariant T cell	9 studies	23% ± 4%	Explore
type I pneumocyte	8 studies	31% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	28% ± 9%	Explore
progenitor cell	8 studies	46% ± 10%	Explore
club cell	7 studies	28% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	31% ± 12%	Explore
goblet cell	7 studies	28% ± 13%	Explore
innate lymphoid cell	7 studies	26% ± 6%	Explore
T follicular helper cell	7 studies	23% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	32% ± 8%	Explore
epithelial cell of proximal tubule	6 studies	43% ± 14%	Explore
renal alpha-intercalated cell	6 studies	43% ± 8%	Explore
neuron	6 studies	41% ± 19%	Explore
erythrocyte	6 studies	43% ± 27%	Explore
respiratory goblet cell	5 studies	29% ± 21%	Explore
leukocyte	5 studies	31% ± 7%	Explore
mononuclear phagocyte	5 studies	33% ± 13%	Explore
kidney loop of Henle epithelial cell	5 studies	34% ± 5%	Explore
enterocyte	5 studies	26% ± 5%	Explore
erythroblast	5 studies	44% ± 21%	Explore
mesothelial cell	5 studies	42% ± 16%	Explore
transit amplifying cell	5 studies	27% ± 8%	Explore
type II pneumocyte	5 studies	34% ± 14%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	33% ± 11%	Explore
hematopoietic precursor cell	4 studies	49% ± 24%	Explore
deuterosomal cell	4 studies	35% ± 10%	Explore
exhausted T cell	4 studies	36% ± 10%	Explore
enteroendocrine cell	4 studies	49% ± 14%	Explore
intestinal crypt stem cell	4 studies	32% ± 11%	Explore
IgG plasma cell	4 studies	22% ± 7%	Explore
retinal ganglion cell	4 studies	60% ± 26%	Explore
retinal cone cell	4 studies	50% ± 23%	Explore
retinal rod cell	4 studies	31% ± 12%	Explore
immature B cell	4 studies	36% ± 15%	Explore
amacrine cell	4 studies	36% ± 18%	Explore
adventitial cell	4 studies	26% ± 9%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	32% ± 4%	Explore
oligodendrocyte precursor cell	4 studies	32% ± 9%	Explore
T-helper 17 cell	4 studies	34% ± 19%	Explore
duct epithelial cell	3 studies	26% ± 1%	Explore
ionocyte	3 studies	24% ± 6%	Explore
precursor cell	3 studies	43% ± 10%	Explore
pancreatic A cell	3 studies	54% ± 25%	Explore
type B pancreatic cell	3 studies	49% ± 24%	Explore
glomerular endothelial cell	3 studies	26% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	54% ± 14%	Explore
neural crest cell	3 studies	44% ± 6%	Explore
extravillous trophoblast	3 studies	44% ± 15%	Explore
placental villous trophoblast	3 studies	58% ± 16%	Explore
common myeloid progenitor	3 studies	37% ± 19%	Explore
hematopoietic stem cell	3 studies	42% ± 11%	Explore
lymphocyte	3 studies	39% ± 8%	Explore
pro-B cell	3 studies	23% ± 2%	Explore
brush cell	3 studies	26% ± 11%	Explore
neuroendocrine cell	3 studies	36% ± 14%	Explore
precursor B cell	3 studies	33% ± 8%	Explore
astrocyte	3 studies	30% ± 17%	Explore
retina horizontal cell	3 studies	33% ± 15%	Explore
microglial cell	3 studies	27% ± 9%	Explore
alveolar macrophage	3 studies	28% ± 2%	Explore
mucus secreting cell	3 studies	38% ± 16%	Explore
serous secreting cell	3 studies	42% ± 17%	Explore
intraepithelial lymphocyte	3 studies	32% ± 7%	Explore
germinal center B cell	3 studies	29% ± 3%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	37% ± 4%	Explore
intermediate monocyte	3 studies	41% ± 16%	Explore
myoepithelial cell	3 studies	32% ± 9%	Explore
granulocyte	3 studies	27% ± 8%	Explore
glutamatergic neuron	3 studies	27% ± 10%	Explore
granulocyte monocyte progenitor cell	3 studies	45% ± 19%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	53% ± 20%	Explore
glial cell	3 studies	38% ± 21%	Explore
hepatocyte	3 studies	47% ± 31%	Explore
group 3 innate lymphoid cell	3 studies	32% ± 14%	Explore
keratinocyte	3 studies	26% ± 6%	Explore
oligodendrocyte	3 studies	19% ± 1%	Explore
T-helper 1 cell	3 studies	35% ± 7%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	31% ± 6%	Explore
progenitor cell of mammary luminal epithelium	3 studies	26% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	17 studies	33% ± 13%	Explore
peripheral blood	14 studies	29% ± 9%	Explore
intestine	9 studies	31% ± 13%	Explore
kidney	7 studies	36% ± 8%	Explore
liver	7 studies	31% ± 22%	Explore
eye	6 studies	29% ± 14%	Explore
lymph node	6 studies	31% ± 15%	Explore
brain	5 studies	24% ± 5%	Explore
uterus	4 studies	42% ± 18%	Explore
breast	4 studies	28% ± 3%	Explore
pancreas	3 studies	50% ± 25%	Explore
placenta	3 studies	45% ± 17%	Explore
bone marrow	3 studies	26% ± 7%	Explore
adrenal gland	3 studies	24% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	2641.29	258 / 258	100%	140.93	230 / 230
esophagus	100%	2080.58	1445 / 1445	100%	70.85	183 / 183
liver	100%	1548.00	226 / 226	100%	92.01	406 / 406
ovary	100%	1627.92	180 / 180	100%	141.41	430 / 430
brain	100%	2287.11	2640 / 2642	100%	126.27	705 / 705
thymus	100%	1974.75	652 / 653	100%	119.60	605 / 605
uterus	100%	2008.80	170 / 170	100%	139.63	458 / 459
skin	100%	2176.96	1809 / 1809	100%	107.11	470 / 472
pancreas	100%	1304.13	328 / 328	99%	89.29	177 / 178
stomach	100%	1554.62	359 / 359	99%	94.23	284 / 286
prostate	100%	2190.22	245 / 245	99%	112.38	498 / 502
kidney	100%	2188.36	89 / 89	99%	86.80	893 / 901
intestine	100%	1920.20	966 / 966	99%	111.45	522 / 527
bladder	100%	2115.24	21 / 21	99%	118.53	497 / 504
lung	100%	1532.96	576 / 578	98%	75.05	1135 / 1155
breast	100%	1833.79	459 / 459	97%	78.94	1079 / 1118
adipose	100%	1810.49	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	138.70	80 / 80
lymph node	0%	0	0 / 0	100%	210.89	29 / 29
spleen	100%	1806.98	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	106.84	45 / 45
ureter	0%	0	0 / 0	100%	172.64	1 / 1
muscle	100%	2653.16	802 / 803	0%	0	0 / 0
blood vessel	100%	2026.66	1333 / 1335	0%	0	0 / 0
heart	100%	2477.94	858 / 861	0%	0	0 / 0
peripheral blood	90%	1142.57	837 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	GADD45GIP1
Protein name	Large ribosomal subunit protein mL64 (39S ribosomal protein L59, mitochondrial) (MRP-L59) (CKII beta-associating protein) (CR6-interacting factor 1) (CRIF1) (Growth arrest and DNA damage-inducible proteins-interacting protein 1) (Papillomavirus L2-interacting nuclear protein 1) (PLINP) (PLINP-1) (p53-responsive gene 6 protein)
Synonyms	PRG6 MRPL59 PLINP1
Description	FUNCTION: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Accessions	Q8TAE8 ENST00000316939.3

GO_0032543	Biological process	mitochondrial translation
GO_0005762	Cellular component	mitochondrial large ribosomal subunit
GO_0005654	Cellular component	nucleoplasm
GO_0005759	Cellular component	mitochondrial matrix
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005739	Cellular component	mitochondrion
GO_0005515	Molecular function	protein binding

GADD45GIP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review