DNAJC8 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	36 studies	34% ± 10%	Explore
B cell	35 studies	29% ± 7%	Explore
endothelial cell	31 studies	33% ± 13%	Explore
CD8-positive, alpha-beta T cell	30 studies	29% ± 9%	Explore
fibroblast	29 studies	33% ± 11%	Explore
macrophage	28 studies	26% ± 9%	Explore
CD4-positive, alpha-beta T cell	27 studies	29% ± 8%	Explore
T cell	25 studies	28% ± 7%	Explore
conventional dendritic cell	25 studies	30% ± 13%	Explore
pericyte	24 studies	30% ± 8%	Explore
smooth muscle cell	21 studies	32% ± 9%	Explore
classical monocyte	21 studies	28% ± 11%	Explore
regulatory T cell	21 studies	32% ± 6%	Explore
naive B cell	19 studies	27% ± 9%	Explore
mast cell	18 studies	29% ± 13%	Explore
memory B cell	18 studies	27% ± 8%	Explore
non-classical monocyte	18 studies	30% ± 13%	Explore
gamma-delta T cell	17 studies	33% ± 14%	Explore
mature NK T cell	16 studies	31% ± 7%	Explore
monocyte	15 studies	26% ± 8%	Explore
basal cell	15 studies	27% ± 12%	Explore
connective tissue cell	15 studies	34% ± 12%	Explore
plasmacytoid dendritic cell	15 studies	35% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	34% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	28% ± 8%	Explore
epithelial cell	14 studies	31% ± 22%	Explore
endothelial cell of lymphatic vessel	13 studies	32% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	32% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	31% ± 9%	Explore
capillary endothelial cell	12 studies	28% ± 6%	Explore
mucosal invariant T cell	12 studies	27% ± 6%	Explore
dendritic cell	11 studies	37% ± 25%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	26% ± 8%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	33% ± 9%	Explore
vein endothelial cell	11 studies	28% ± 7%	Explore
endothelial cell of vascular tree	11 studies	28% ± 7%	Explore
myeloid cell	11 studies	32% ± 14%	Explore
ciliated cell	11 studies	31% ± 15%	Explore
myofibroblast cell	10 studies	37% ± 9%	Explore
endothelial cell of artery	10 studies	28% ± 6%	Explore
plasma cell	9 studies	29% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	34% ± 9%	Explore
abnormal cell	8 studies	27% ± 9%	Explore
plasmablast	7 studies	37% ± 19%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	37% ± 13%	Explore
progenitor cell	7 studies	30% ± 14%	Explore
secretory cell	7 studies	26% ± 14%	Explore
hematopoietic precursor cell	6 studies	39% ± 20%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	31% ± 11%	Explore
precursor B cell	6 studies	39% ± 13%	Explore
innate lymphoid cell	6 studies	31% ± 5%	Explore
neuron	6 studies	32% ± 16%	Explore
T follicular helper cell	6 studies	28% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	32% ± 7%	Explore
alveolar macrophage	5 studies	18% ± 1%	Explore
type I pneumocyte	5 studies	27% ± 9%	Explore
leukocyte	5 studies	37% ± 11%	Explore
mononuclear phagocyte	5 studies	29% ± 12%	Explore
epithelial cell of proximal tubule	5 studies	22% ± 9%	Explore
mesothelial cell	5 studies	31% ± 14%	Explore
hematopoietic stem cell	5 studies	34% ± 12%	Explore
pro-B cell	5 studies	37% ± 5%	Explore
type II pneumocyte	5 studies	27% ± 15%	Explore
astrocyte	5 studies	22% ± 11%	Explore
glutamatergic neuron	5 studies	37% ± 13%	Explore
oligodendrocyte precursor cell	5 studies	28% ± 6%	Explore
pancreatic A cell	4 studies	45% ± 8%	Explore
exhausted T cell	4 studies	41% ± 10%	Explore
kidney loop of Henle epithelial cell	4 studies	26% ± 5%	Explore
retinal ganglion cell	4 studies	54% ± 28%	Explore
erythroblast	4 studies	45% ± 19%	Explore
immature B cell	4 studies	30% ± 9%	Explore
amacrine cell	4 studies	43% ± 19%	Explore
retina horizontal cell	4 studies	40% ± 19%	Explore
retinal rod cell	4 studies	38% ± 16%	Explore
microglial cell	4 studies	23% ± 5%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	26% ± 6%	Explore
granulocyte	4 studies	24% ± 7%	Explore
GABAergic neuron	4 studies	29% ± 9%	Explore
enteroendocrine cell	4 studies	26% ± 11%	Explore
interneuron	4 studies	29% ± 10%	Explore
oligodendrocyte	4 studies	23% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	30% ± 9%	Explore
pancreatic D cell	3 studies	39% ± 19%	Explore
type B pancreatic cell	3 studies	43% ± 11%	Explore
platelet	3 studies	19% ± 2%	Explore
glomerular endothelial cell	3 studies	27% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	39% ± 13%	Explore
neural crest cell	3 studies	37% ± 0%	Explore
retinal bipolar neuron	3 studies	44% ± 17%	Explore
placental villous trophoblast	3 studies	47% ± 10%	Explore
lymphocyte	3 studies	41% ± 8%	Explore
megakaryocyte	3 studies	25% ± 7%	Explore
club cell	3 studies	29% ± 9%	Explore
retinal cone cell	3 studies	51% ± 10%	Explore
intraepithelial lymphocyte	3 studies	36% ± 14%	Explore
Mueller cell	3 studies	36% ± 8%	Explore
germinal center B cell	3 studies	34% ± 6%	Explore
intermediate monocyte	3 studies	41% ± 19%	Explore
CD4-positive helper T cell	3 studies	31% ± 9%	Explore
myoepithelial cell	3 studies	30% ± 6%	Explore
pancreatic ductal cell	3 studies	52% ± 13%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	46% ± 26%	Explore
intestinal crypt stem cell	3 studies	23% ± 4%	Explore
erythrocyte	3 studies	45% ± 18%	Explore
group 3 innate lymphoid cell	3 studies	38% ± 16%	Explore
transit amplifying cell	3 studies	21% ± 2%	Explore
T-helper 17 cell	3 studies	31% ± 3%	Explore
T-helper 1 cell	3 studies	28% ± 3%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	31% ± 5%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	29% ± 8%	Explore
double negative thymocyte	3 studies	49% ± 15%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	16 studies	32% ± 9%	Explore
lung	13 studies	32% ± 13%	Explore
intestine	9 studies	25% ± 12%	Explore
brain	9 studies	27% ± 7%	Explore
kidney	7 studies	26% ± 8%	Explore
eye	7 studies	33% ± 15%	Explore
bone marrow	5 studies	25% ± 6%	Explore
lymph node	5 studies	26% ± 3%	Explore
pancreas	4 studies	39% ± 14%	Explore
uterus	4 studies	37% ± 13%	Explore
breast	4 studies	24% ± 5%	Explore
liver	4 studies	36% ± 21%	Explore
placenta	3 studies	36% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4587.71	1445 / 1445	100%	69.32	183 / 183
intestine	100%	4912.02	966 / 966	100%	88.45	527 / 527
lung	100%	4487.24	578 / 578	100%	101.21	1155 / 1155
ovary	100%	4894.17	180 / 180	100%	97.50	430 / 430
prostate	100%	4354.25	245 / 245	100%	101.08	502 / 502
stomach	100%	3336.00	359 / 359	100%	80.06	286 / 286
uterus	100%	5692.61	170 / 170	100%	141.10	459 / 459
brain	100%	4937.69	2641 / 2642	100%	136.31	705 / 705
breast	100%	5254.31	459 / 459	100%	109.48	1117 / 1118
kidney	100%	4164.06	89 / 89	100%	90.97	900 / 901
thymus	100%	4776.27	653 / 653	100%	139.73	604 / 605
bladder	100%	4957.95	21 / 21	100%	106.33	503 / 504
skin	100%	4735.96	1809 / 1809	100%	134.57	471 / 472
liver	100%	2156.51	225 / 226	100%	63.36	406 / 406
adrenal gland	100%	4395.16	258 / 258	99%	72.48	227 / 230
pancreas	98%	1581.16	321 / 328	99%	86.29	177 / 178
adipose	100%	5207.87	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5645.72	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	171.71	29 / 29
spleen	100%	4696.07	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	120.05	45 / 45
ureter	0%	0	0 / 0	100%	87.79	1 / 1
muscle	100%	2941.55	800 / 803	0%	0	0 / 0
heart	98%	3101.06	848 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	98%	70.37	78 / 80
peripheral blood	93%	3237.44	861 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0