CAP1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	43 studies	48% ± 16%	Explore
macrophage	42 studies	51% ± 16%	Explore
endothelial cell	37 studies	33% ± 12%	Explore
CD8-positive, alpha-beta T cell	37 studies	46% ± 17%	Explore
B cell	36 studies	39% ± 14%	Explore
T cell	36 studies	40% ± 17%	Explore
CD4-positive, alpha-beta T cell	31 studies	44% ± 16%	Explore
fibroblast	30 studies	27% ± 11%	Explore
conventional dendritic cell	30 studies	65% ± 16%	Explore
pericyte	29 studies	37% ± 12%	Explore
classical monocyte	27 studies	58% ± 15%	Explore
regulatory T cell	27 studies	46% ± 17%	Explore
dendritic cell	26 studies	54% ± 21%	Explore
smooth muscle cell	26 studies	36% ± 12%	Explore
monocyte	25 studies	53% ± 17%	Explore
non-classical monocyte	24 studies	71% ± 13%	Explore
mast cell	21 studies	40% ± 16%	Explore
mature NK T cell	20 studies	47% ± 12%	Explore
memory B cell	20 studies	37% ± 10%	Explore
gamma-delta T cell	19 studies	45% ± 15%	Explore
plasmacytoid dendritic cell	19 studies	51% ± 13%	Explore
naive B cell	18 studies	35% ± 10%	Explore
myeloid cell	18 studies	47% ± 22%	Explore
epithelial cell	17 studies	34% ± 18%	Explore
endothelial cell of lymphatic vessel	15 studies	32% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	43% ± 16%	Explore
mucosal invariant T cell	15 studies	40% ± 15%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	42% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	57% ± 14%	Explore
basal cell	15 studies	33% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	34% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	14 studies	46% ± 17%	Explore
myofibroblast cell	14 studies	33% ± 12%	Explore
plasma cell	13 studies	30% ± 11%	Explore
neutrophil	13 studies	48% ± 12%	Explore
capillary endothelial cell	13 studies	31% ± 7%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	44% ± 19%	Explore
connective tissue cell	12 studies	34% ± 12%	Explore
vein endothelial cell	12 studies	30% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	45% ± 15%	Explore
endothelial cell of artery	11 studies	28% ± 9%	Explore
endothelial cell of vascular tree	11 studies	31% ± 6%	Explore
plasmablast	10 studies	39% ± 19%	Explore
platelet	10 studies	47% ± 14%	Explore
leukocyte	10 studies	39% ± 14%	Explore
microglial cell	10 studies	35% ± 17%	Explore
innate lymphoid cell	9 studies	33% ± 11%	Explore
goblet cell	9 studies	30% ± 11%	Explore
abnormal cell	9 studies	27% ± 10%	Explore
type I pneumocyte	8 studies	29% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	57% ± 23%	Explore
ciliated cell	8 studies	35% ± 12%	Explore
alveolar macrophage	7 studies	55% ± 17%	Explore
secretory cell	7 studies	36% ± 10%	Explore
T follicular helper cell	7 studies	36% ± 7%	Explore
CD4-positive helper T cell	6 studies	28% ± 10%	Explore
hematopoietic precursor cell	6 studies	49% ± 17%	Explore
club cell	6 studies	28% ± 13%	Explore
respiratory goblet cell	6 studies	28% ± 10%	Explore
mononuclear phagocyte	6 studies	57% ± 16%	Explore
megakaryocyte	6 studies	75% ± 15%	Explore
neuron	6 studies	36% ± 13%	Explore
enterocyte	6 studies	23% ± 7%	Explore
hematopoietic stem cell	6 studies	41% ± 13%	Explore
precursor B cell	6 studies	44% ± 13%	Explore
astrocyte	6 studies	23% ± 10%	Explore
oligodendrocyte	6 studies	19% ± 3%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	51% ± 22%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	39% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	47% ± 17%	Explore
exhausted T cell	5 studies	64% ± 14%	Explore
kidney loop of Henle epithelial cell	5 studies	18% ± 3%	Explore
transit amplifying cell	5 studies	21% ± 4%	Explore
lymphocyte	5 studies	42% ± 16%	Explore
brush cell	5 studies	29% ± 12%	Explore
double negative thymocyte	5 studies	55% ± 11%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	66% ± 25%	Explore
intermediate monocyte	5 studies	66% ± 19%	Explore
granulocyte	5 studies	44% ± 19%	Explore
oligodendrocyte precursor cell	5 studies	23% ± 4%	Explore
ionocyte	4 studies	26% ± 7%	Explore
squamous epithelial cell	4 studies	45% ± 16%	Explore
progenitor cell	4 studies	36% ± 16%	Explore
retinal ganglion cell	4 studies	54% ± 29%	Explore
pro-B cell	4 studies	40% ± 6%	Explore
immature B cell	4 studies	53% ± 8%	Explore
adventitial cell	4 studies	22% ± 5%	Explore
glial cell	4 studies	32% ± 16%	Explore
inflammatory macrophage	4 studies	44% ± 9%	Explore
germinal center B cell	4 studies	47% ± 18%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	30% ± 5%	Explore
T-helper 17 cell	4 studies	52% ± 23%	Explore
T-helper 1 cell	4 studies	58% ± 16%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	56% ± 24%	Explore
pancreatic A cell	3 studies	54% ± 11%	Explore
monocyte-derived dendritic cell	3 studies	58% ± 29%	Explore
glomerular endothelial cell	3 studies	27% ± 5%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	19% ± 1%	Explore
epithelial cell of proximal tubule	3 studies	18% ± 2%	Explore
extravillous trophoblast	3 studies	60% ± 13%	Explore
placental villous trophoblast	3 studies	42% ± 6%	Explore
serous secreting cell	3 studies	17% ± 2%	Explore
tissue-resident macrophage	3 studies	48% ± 11%	Explore
intraepithelial lymphocyte	3 studies	47% ± 7%	Explore
Mueller cell	3 studies	31% ± 5%	Explore
muscle cell	3 studies	40% ± 23%	Explore
GABAergic neuron	3 studies	28% ± 6%	Explore
glutamatergic neuron	3 studies	43% ± 8%	Explore
pancreatic ductal cell	3 studies	70% ± 20%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	64% ± 9%	Explore
enteroendocrine cell	3 studies	38% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	45% ± 13%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	45% ± 14%	Explore
erythrocyte	3 studies	33% ± 7%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	20 studies	45% ± 14%	Explore
lung	19 studies	35% ± 12%	Explore
intestine	11 studies	26% ± 9%	Explore
brain	8 studies	33% ± 11%	Explore
kidney	7 studies	33% ± 14%	Explore
eye	6 studies	22% ± 7%	Explore
liver	6 studies	31% ± 13%	Explore
bone marrow	5 studies	39% ± 13%	Explore
lymph node	5 studies	41% ± 16%	Explore
pancreas	4 studies	44% ± 20%	Explore
uterus	4 studies	41% ± 14%	Explore
breast	4 studies	27% ± 4%	Explore
placenta	3 studies	50% ± 6%	Explore
skin	3 studies	24% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	16112.47	459 / 459	100%	371.24	1118 / 1118
esophagus	100%	22989.45	1445 / 1445	100%	413.72	183 / 183
intestine	100%	18240.67	966 / 966	100%	328.39	527 / 527
lung	100%	21546.23	578 / 578	100%	322.38	1155 / 1155
ovary	100%	9484.29	180 / 180	100%	241.28	430 / 430
uterus	100%	18030.15	170 / 170	100%	322.81	459 / 459
skin	100%	18371.77	1808 / 1809	100%	419.57	471 / 472
thymus	100%	12463.98	652 / 653	100%	280.78	604 / 605
bladder	100%	17931.10	21 / 21	100%	348.73	502 / 504
prostate	100%	11623.51	244 / 245	100%	193.95	501 / 502
kidney	100%	11778.17	89 / 89	99%	250.67	894 / 901
stomach	99%	12130.63	355 / 359	100%	304.58	286 / 286
brain	95%	8080.27	2516 / 2642	100%	233.55	705 / 705
adrenal gland	99%	10096.83	255 / 258	92%	134.08	211 / 230
liver	73%	4964.46	165 / 226	98%	137.34	397 / 406
pancreas	68%	3711.76	224 / 328	99%	379.69	176 / 178
adipose	100%	18453.01	1204 / 1204	0%	0	0 / 0
blood vessel	100%	31283.33	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	383.72	29 / 29
spleen	100%	22908.49	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	337.33	45 / 45
ureter	0%	0	0 / 0	100%	122.16	1 / 1
peripheral blood	100%	58567.52	928 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	96%	153.98	77 / 80
heart	81%	5457.50	700 / 861	0%	0	0 / 0
muscle	34%	1627.66	273 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0