C1orf43 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	31 studies	28% ± 13%	Explore
macrophage	27 studies	28% ± 9%	Explore
natural killer cell	24 studies	23% ± 6%	Explore
conventional dendritic cell	23 studies	31% ± 15%	Explore
CD4-positive, alpha-beta T cell	22 studies	26% ± 9%	Explore
B cell	21 studies	23% ± 7%	Explore
classical monocyte	21 studies	29% ± 10%	Explore
non-classical monocyte	20 studies	31% ± 11%	Explore
smooth muscle cell	19 studies	23% ± 8%	Explore
fibroblast	19 studies	26% ± 11%	Explore
pericyte	19 studies	25% ± 7%	Explore
regulatory T cell	19 studies	29% ± 8%	Explore
memory B cell	18 studies	22% ± 5%	Explore
CD8-positive, alpha-beta T cell	18 studies	26% ± 8%	Explore
plasmacytoid dendritic cell	17 studies	32% ± 11%	Explore
basal cell	16 studies	30% ± 14%	Explore
monocyte	16 studies	27% ± 8%	Explore
naive B cell	16 studies	21% ± 6%	Explore
T cell	15 studies	23% ± 6%	Explore
endothelial cell of lymphatic vessel	13 studies	33% ± 10%	Explore
epithelial cell	13 studies	41% ± 21%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	22% ± 6%	Explore
ciliated cell	12 studies	36% ± 13%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	20% ± 5%	Explore
myofibroblast cell	12 studies	25% ± 9%	Explore
connective tissue cell	12 studies	24% ± 6%	Explore
gamma-delta T cell	12 studies	25% ± 12%	Explore
plasma cell	11 studies	32% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	23% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	22% ± 4%	Explore
vein endothelial cell	11 studies	25% ± 6%	Explore
capillary endothelial cell	10 studies	26% ± 7%	Explore
endothelial cell of artery	10 studies	24% ± 6%	Explore
dendritic cell	10 studies	36% ± 19%	Explore
endothelial cell of vascular tree	10 studies	29% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	26% ± 9%	Explore
mucosal invariant T cell	9 studies	21% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	30% ± 10%	Explore
secretory cell	8 studies	27% ± 10%	Explore
mature NK T cell	8 studies	20% ± 2%	Explore
abnormal cell	8 studies	40% ± 18%	Explore
myeloid cell	8 studies	34% ± 10%	Explore
mast cell	8 studies	21% ± 5%	Explore
type I pneumocyte	7 studies	28% ± 13%	Explore
plasmablast	7 studies	39% ± 23%	Explore
epithelial cell of proximal tubule	7 studies	30% ± 8%	Explore
progenitor cell	7 studies	23% ± 6%	Explore
goblet cell	7 studies	24% ± 11%	Explore
neuron	7 studies	40% ± 21%	Explore
T follicular helper cell	7 studies	23% ± 4%	Explore
hematopoietic precursor cell	6 studies	33% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	23% ± 5%	Explore
enterocyte	6 studies	22% ± 3%	Explore
hematopoietic stem cell	6 studies	25% ± 7%	Explore
precursor B cell	6 studies	30% ± 11%	Explore
innate lymphoid cell	6 studies	21% ± 3%	Explore
type II pneumocyte	6 studies	37% ± 16%	Explore
mononuclear phagocyte	5 studies	29% ± 14%	Explore
kidney loop of Henle epithelial cell	5 studies	26% ± 5%	Explore
enteroendocrine cell	5 studies	35% ± 13%	Explore
intestinal crypt stem cell	5 studies	23% ± 6%	Explore
mesothelial cell	5 studies	31% ± 17%	Explore
pro-B cell	5 studies	31% ± 7%	Explore
astrocyte	5 studies	30% ± 10%	Explore
alveolar macrophage	5 studies	25% ± 5%	Explore
oligodendrocyte	5 studies	27% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	27% ± 5%	Explore
oligodendrocyte precursor cell	5 studies	29% ± 6%	Explore
club cell	4 studies	28% ± 8%	Explore
deuterosomal cell	4 studies	24% ± 6%	Explore
pancreatic A cell	4 studies	70% ± 14%	Explore
type B pancreatic cell	4 studies	68% ± 22%	Explore
exhausted T cell	4 studies	33% ± 8%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	35% ± 6%	Explore
renal alpha-intercalated cell	4 studies	33% ± 8%	Explore
leukocyte	4 studies	29% ± 5%	Explore
transit amplifying cell	4 studies	19% ± 2%	Explore
erythroblast	4 studies	32% ± 14%	Explore
megakaryocyte	4 studies	32% ± 8%	Explore
immature B cell	4 studies	24% ± 7%	Explore
retina horizontal cell	4 studies	34% ± 16%	Explore
retinal rod cell	4 studies	35% ± 18%	Explore
microglial cell	4 studies	26% ± 8%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	39% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	30% ± 6%	Explore
GABAergic neuron	4 studies	32% ± 12%	Explore
glutamatergic neuron	4 studies	39% ± 16%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	34% ± 11%	Explore
respiratory goblet cell	3 studies	34% ± 18%	Explore
squamous epithelial cell	3 studies	40% ± 23%	Explore
pancreatic D cell	3 studies	64% ± 17%	Explore
neural crest cell	3 studies	25% ± 6%	Explore
retinal bipolar neuron	3 studies	48% ± 18%	Explore
OFF-bipolar cell	3 studies	41% ± 28%	Explore
ON-bipolar cell	3 studies	40% ± 27%	Explore
retinal ganglion cell	3 studies	80% ± 12%	Explore
common myeloid progenitor	3 studies	31% ± 18%	Explore
lymphocyte	3 studies	29% ± 4%	Explore
brush cell	3 studies	34% ± 9%	Explore
amacrine cell	3 studies	51% ± 10%	Explore
retinal cone cell	3 studies	62% ± 24%	Explore
serous secreting cell	3 studies	26% ± 3%	Explore
Mueller cell	3 studies	27% ± 6%	Explore
acinar cell	3 studies	42% ± 28%	Explore
muscle cell	3 studies	31% ± 16%	Explore
germinal center B cell	3 studies	27% ± 2%	Explore
intermediate monocyte	3 studies	43% ± 16%	Explore
pancreatic ductal cell	3 studies	61% ± 19%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	45% ± 24%	Explore
erythrocyte	3 studies	33% ± 15%	Explore
group 3 innate lymphoid cell	3 studies	31% ± 10%	Explore
interneuron	3 studies	27% ± 15%	Explore
T-helper 1 cell	3 studies	28% ± 11%	Explore
T-helper 17 cell	3 studies	31% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	20% ± 3%	Explore
double negative thymocyte	3 studies	35% ± 16%	Explore
progenitor cell of mammary luminal epithelium	3 studies	25% ± 6%	Explore
hepatocyte	3 studies	44% ± 26%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	26% ± 7%	Explore
lung	13 studies	31% ± 10%	Explore
kidney	8 studies	26% ± 5%	Explore
intestine	8 studies	24% ± 10%	Explore
eye	8 studies	29% ± 16%	Explore
brain	8 studies	28% ± 11%	Explore
liver	5 studies	29% ± 15%	Explore
pancreas	4 studies	63% ± 22%	Explore
bone marrow	4 studies	20% ± 2%	Explore
lymph node	4 studies	31% ± 15%	Explore
breast	4 studies	24% ± 6%	Explore
uterus	3 studies	30% ± 13%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	9067.69	2642 / 2642	100%	257.34	705 / 705
breast	100%	8381.98	459 / 459	100%	444.26	1118 / 1118
esophagus	100%	7042.00	1445 / 1445	100%	199.28	183 / 183
liver	100%	6910.50	226 / 226	100%	311.11	406 / 406
lung	100%	8409.64	578 / 578	100%	321.43	1155 / 1155
ovary	100%	5531.26	180 / 180	100%	271.74	430 / 430
pancreas	100%	5607.89	328 / 328	100%	227.41	178 / 178
prostate	100%	7047.02	245 / 245	100%	309.26	502 / 502
stomach	100%	6744.63	359 / 359	100%	230.70	286 / 286
uterus	100%	6222.99	170 / 170	100%	264.24	459 / 459
thymus	100%	6837.48	653 / 653	100%	256.87	604 / 605
skin	100%	8265.52	1809 / 1809	100%	369.73	471 / 472
intestine	100%	7380.18	966 / 966	100%	262.11	525 / 527
bladder	100%	7378.33	21 / 21	99%	266.83	501 / 504
kidney	100%	9617.25	89 / 89	99%	236.87	893 / 901
adrenal gland	100%	9533.26	258 / 258	96%	241.86	220 / 230
adipose	100%	8953.33	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	266.75	80 / 80
lymph node	0%	0	0 / 0	100%	190.63	29 / 29
muscle	100%	16770.37	803 / 803	0%	0	0 / 0
spleen	100%	6077.29	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	219.42	45 / 45
ureter	0%	0	0 / 0	100%	144.70	1 / 1
blood vessel	100%	7739.90	1334 / 1335	0%	0	0 / 0
heart	98%	8217.15	845 / 861	0%	0	0 / 0
peripheral blood	97%	5908.66	900 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	C1orf43
Protein name	Chromosome 1 open reading frame 43 Protein C1orf43 (Hepatitis C virus NS5A-transactivated protein 4) (HCV NS5A-transactivated protein 4) (Protein NICE-3) (S863-3) Chromosome 1 open reading frame 43, isoform CRA_b (NS5ATP4A)
Synonyms	NS5ATP4 hCG_1818084 NICE3 HSPC012 NS5ATP4A
Description	FUNCTION: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages. . FUNCTION: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages. . FUNCTION: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages. . FUNCTION: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages. . FUNCTION: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages. . FUNCTION: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages. . FUNCTION: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages. .
Accessions	Q9BWL3 ENST00000368521.10 [Q9BWL3-1] ENST00000470180.2 X6R6S3 ENST00000368519.5 X6R6F3 ENST00000648267.1 A0A1W2PQP6 ENST00000368516.1 Q09GN0 ENST00000368518.5 [Q9BWL3-3] ENST00000640799.1 ENST00000362076.8 [Q9BWL3-4] A0A1W2PQS0 ENST00000350592.7 [Q9BWL3-2] A0A3B3IS96

GO_0001701	Biological process	in utero embryonic development
GO_0006909	Biological process	phagocytosis
GO_0005829	Cellular component	cytosol
GO_0005794	Cellular component	Golgi apparatus
GO_0016020	Cellular component	membrane
GO_0005739	Cellular component	mitochondrion

C1orf43 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review