ZNF638 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	40 studies	41% ± 20%	Explore
fibroblast	30 studies	37% ± 19%	Explore
pericyte	25 studies	34% ± 19%	Explore
smooth muscle cell	21 studies	33% ± 16%	Explore
B cell	20 studies	25% ± 10%	Explore
astrocyte	20 studies	54% ± 19%	Explore
macrophage	19 studies	36% ± 21%	Explore
natural killer cell	18 studies	22% ± 7%	Explore
CD4-positive, alpha-beta T cell	18 studies	21% ± 6%	Explore
microglial cell	17 studies	53% ± 19%	Explore
regulatory T cell	17 studies	22% ± 6%	Explore
oligodendrocyte precursor cell	16 studies	59% ± 22%	Explore
endothelial cell of lymphatic vessel	15 studies	34% ± 20%	Explore
ciliated cell	15 studies	30% ± 11%	Explore
oligodendrocyte	15 studies	73% ± 15%	Explore
CD8-positive, alpha-beta T cell	15 studies	22% ± 5%	Explore
memory B cell	15 studies	18% ± 3%	Explore
T cell	13 studies	25% ± 9%	Explore
mast cell	13 studies	31% ± 12%	Explore
basal cell	13 studies	35% ± 20%	Explore
naive B cell	13 studies	21% ± 3%	Explore
glutamatergic neuron	12 studies	67% ± 22%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	22% ± 5%	Explore
capillary endothelial cell	12 studies	24% ± 9%	Explore
epithelial cell	12 studies	43% ± 22%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	11 studies	22% ± 6%	Explore
GABAergic neuron	11 studies	64% ± 23%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	19% ± 4%	Explore
type I pneumocyte	10 studies	31% ± 13%	Explore
endothelial cell of artery	10 studies	22% ± 6%	Explore
adipocyte	10 studies	51% ± 16%	Explore
gamma-delta T cell	10 studies	22% ± 10%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	20% ± 5%	Explore
neuron	9 studies	52% ± 24%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	20% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	24% ± 7%	Explore
myofibroblast cell	8 studies	30% ± 15%	Explore
amacrine cell	8 studies	49% ± 18%	Explore
mucosal invariant T cell	8 studies	22% ± 6%	Explore
myeloid cell	8 studies	33% ± 10%	Explore
vein endothelial cell	8 studies	31% ± 21%	Explore
plasmacytoid dendritic cell	8 studies	21% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	19% ± 3%	Explore
leukocyte	7 studies	39% ± 19%	Explore
mature NK T cell	7 studies	22% ± 12%	Explore
connective tissue cell	7 studies	28% ± 13%	Explore
type II pneumocyte	7 studies	37% ± 14%	Explore
retinal cone cell	7 studies	48% ± 19%	Explore
retinal rod cell	7 studies	41% ± 19%	Explore
dendritic cell	7 studies	39% ± 9%	Explore
classical monocyte	6 studies	21% ± 7%	Explore
abnormal cell	6 studies	36% ± 19%	Explore
interneuron	6 studies	76% ± 15%	Explore
retinal ganglion cell	6 studies	50% ± 21%	Explore
club cell	6 studies	40% ± 13%	Explore
retina horizontal cell	6 studies	51% ± 21%	Explore
cardiac muscle cell	6 studies	60% ± 24%	Explore
mesothelial cell	6 studies	44% ± 15%	Explore
Mueller cell	6 studies	54% ± 22%	Explore
T follicular helper cell	6 studies	19% ± 3%	Explore
endothelial cell of vascular tree	6 studies	35% ± 21%	Explore
secretory cell	5 studies	23% ± 5%	Explore
hepatocyte	5 studies	57% ± 29%	Explore
non-classical monocyte	5 studies	23% ± 5%	Explore
progenitor cell	5 studies	42% ± 19%	Explore
retinal bipolar neuron	5 studies	44% ± 17%	Explore
glial cell	5 studies	45% ± 15%	Explore
brush cell	5 studies	32% ± 7%	Explore
lymphocyte	5 studies	39% ± 19%	Explore
monocyte	5 studies	41% ± 6%	Explore
goblet cell	5 studies	34% ± 26%	Explore
differentiation-committed oligodendrocyte precursor	4 studies	57% ± 23%	Explore
granule cell	4 studies	64% ± 6%	Explore
plasma cell	4 studies	39% ± 7%	Explore
retinal pigment epithelial cell	4 studies	50% ± 26%	Explore
OFF-bipolar cell	4 studies	45% ± 22%	Explore
ON-bipolar cell	4 studies	50% ± 23%	Explore
respiratory goblet cell	4 studies	43% ± 13%	Explore
muscle cell	4 studies	44% ± 28%	Explore
enteroendocrine cell	4 studies	26% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	23% ± 7%	Explore
hematopoietic precursor cell	3 studies	32% ± 9%	Explore
ionocyte	3 studies	31% ± 8%	Explore
conventional dendritic cell	3 studies	29% ± 13%	Explore
exhausted T cell	3 studies	23% ± 7%	Explore
glomerular endothelial cell	3 studies	20% ± 2%	Explore
podocyte	3 studies	35% ± 14%	Explore
renal beta-intercalated cell	3 studies	34% ± 13%	Explore
neural crest cell	3 studies	20% ± 1%	Explore
GABAergic interneuron	3 studies	68% ± 1%	Explore
pro-B cell	3 studies	27% ± 5%	Explore
endocardial cell	3 studies	38% ± 13%	Explore
mononuclear phagocyte	3 studies	34% ± 7%	Explore
GABAergic amacrine cell	3 studies	65% ± 15%	Explore
glycinergic amacrine cell	3 studies	61% ± 12%	Explore
rod bipolar cell	3 studies	54% ± 18%	Explore
innate lymphoid cell	3 studies	19% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	20% ± 4%	Explore
ependymal cell	3 studies	68% ± 14%	Explore
hematopoietic stem cell	3 studies	26% ± 9%	Explore
adventitial cell	3 studies	38% ± 12%	Explore
alveolar macrophage	3 studies	47% ± 12%	Explore
chondrocyte	3 studies	48% ± 17%	Explore
group 3 innate lymphoid cell	3 studies	28% ± 9%	Explore
Schwann cell	3 studies	48% ± 28%	Explore
transit amplifying cell	3 studies	44% ± 36%	Explore
immature B cell	3 studies	21% ± 4%	Explore
double negative thymocyte	3 studies	26% ± 11%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	36% ± 16%	Explore
kidney loop of Henle epithelial cell	3 studies	36% ± 15%	Explore
renal principal cell	3 studies	37% ± 13%	Explore
mural cell	3 studies	53% ± 5%	Explore
mucus secreting cell	3 studies	46% ± 6%	Explore
myoepithelial cell	3 studies	36% ± 20%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	19 studies	60% ± 23%	Explore
lung	13 studies	28% ± 11%	Explore
peripheral blood	10 studies	20% ± 6%	Explore
eye	9 studies	47% ± 24%	Explore
kidney	7 studies	28% ± 14%	Explore
heart	6 studies	43% ± 19%	Explore
liver	5 studies	38% ± 22%	Explore
intestine	4 studies	24% ± 8%	Explore
adipose	4 studies	44% ± 17%	Explore
lymph node	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	7723.81	459 / 459	100%	42.46	1118 / 1118
esophagus	100%	6686.71	1445 / 1445	100%	26.76	183 / 183
prostate	100%	9006.58	245 / 245	100%	30.15	502 / 502
thymus	100%	9437.68	653 / 653	100%	34.71	604 / 605
uterus	100%	9241.20	170 / 170	100%	31.36	458 / 459
lung	100%	6925.81	578 / 578	100%	25.44	1152 / 1155
brain	100%	7721.73	2640 / 2642	99%	31.43	701 / 705
bladder	100%	7521.38	21 / 21	99%	24.89	500 / 504
pancreas	100%	3816.06	327 / 328	99%	24.34	177 / 178
liver	100%	4951.75	226 / 226	99%	16.35	402 / 406
adrenal gland	100%	6777.55	258 / 258	99%	23.67	227 / 230
kidney	100%	6053.82	89 / 89	98%	24.02	886 / 901
stomach	100%	5385.47	359 / 359	97%	18.59	277 / 286
ovary	100%	10613.34	180 / 180	97%	14.63	416 / 430
intestine	100%	7602.44	966 / 966	96%	19.14	508 / 527
skin	100%	6475.36	1809 / 1809	95%	25.45	447 / 472
blood vessel	100%	6675.05	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	22.19	29 / 29
muscle	100%	6223.33	803 / 803	0%	0	0 / 0
spleen	100%	8294.15	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	24.51	45 / 45
ureter	0%	0	0 / 0	100%	11.39	1 / 1
adipose	100%	7424.88	1203 / 1204	0%	0	0 / 0
heart	99%	4950.86	851 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	78%	14.31	62 / 80
peripheral blood	71%	2908.62	664 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	ZNF638
Protein name	Zinc finger protein 638 (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL-associated antigen se33-1) (Nuclear protein 220) (Zinc finger matrin-like protein) Zinc finger protein 638
Synonyms	ZFML NP220
Description	FUNCTION: Transcription factor that binds to cytidine clusters in double-stranded DNA . Plays a key role in the silencing of unintegrated retroviral DNA: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed . Mediates transcriptional repression of unintegrated viral DNA by specifically binding to the cytidine clusters of retroviral DNA and mediating the recruitment of chromatin silencers, such as the HUSH complex, SETDB1 and the histone deacetylases HDAC1 and HDAC4 . Acts as an early regulator of adipogenesis by acting as a transcription cofactor of CEBPs (CEBPA, CEBPD and/or CEBPG), controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1 (By similarity). May also regulate alternative splicing of target genes during adipogenesis (By similarity). .
Accessions	ENST00000461991.3 ENST00000454122.1 ENST00000475743.1 ENST00000454278.5 ENST00000455226.5 ENST00000264447.9 [Q14966-1] A0A096LNQ0 Q14966 A0A096LPB4 A0A096LNS4 C9JMR2 C9JWN0 A0A096LNR2 ENST00000437658.2 A0A096LPI0 C9JHV0 A0A096LNX0 ENST00000410075.5 [Q14966-6] ENST00000409544.5 [Q14966-1] ENST00000466330.5 A0A096LPK8 C9JSD0 ENST00000417778.5 ENST00000493576.6 ENST00000494621.5 ENST00000464375.5 ENST00000466975.5

GO_0043484	Biological process	regulation of RNA splicing
GO_0008380	Biological process	RNA splicing
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0016607	Cellular component	nuclear speck
GO_0005654	Cellular component	nucleoplasm
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0003690	Molecular function	double-stranded DNA binding
GO_0003729	Molecular function	mRNA binding
GO_0008270	Molecular function	zinc ion binding
GO_0003723	Molecular function	RNA binding

ZNF638 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review