PSMG2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	24 studies	23% ± 8%	Explore
fibroblast	24 studies	26% ± 10%	Explore
endothelial cell	24 studies	25% ± 10%	Explore
conventional dendritic cell	21 studies	28% ± 13%	Explore
B cell	20 studies	23% ± 7%	Explore
CD4-positive, alpha-beta T cell	20 studies	25% ± 9%	Explore
macrophage	19 studies	23% ± 8%	Explore
regulatory T cell	19 studies	25% ± 6%	Explore
T cell	17 studies	24% ± 6%	Explore
classical monocyte	17 studies	24% ± 10%	Explore
CD8-positive, alpha-beta T cell	17 studies	28% ± 8%	Explore
non-classical monocyte	15 studies	26% ± 13%	Explore
pericyte	15 studies	22% ± 6%	Explore
smooth muscle cell	14 studies	21% ± 5%	Explore
naive B cell	12 studies	20% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	20% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	23% ± 5%	Explore
monocyte	11 studies	22% ± 4%	Explore
memory B cell	11 studies	21% ± 4%	Explore
plasmacytoid dendritic cell	11 studies	26% ± 8%	Explore
gamma-delta T cell	11 studies	24% ± 13%	Explore
basal cell	10 studies	31% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	22% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	22% ± 5%	Explore
mature NK T cell	10 studies	20% ± 3%	Explore
connective tissue cell	10 studies	24% ± 5%	Explore
epithelial cell	10 studies	37% ± 19%	Explore
endothelial cell of lymphatic vessel	10 studies	20% ± 7%	Explore
myofibroblast cell	9 studies	23% ± 5%	Explore
abnormal cell	9 studies	23% ± 8%	Explore
mucosal invariant T cell	9 studies	21% ± 3%	Explore
mast cell	8 studies	18% ± 2%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	24% ± 10%	Explore
capillary endothelial cell	8 studies	18% ± 3%	Explore
dendritic cell	8 studies	35% ± 21%	Explore
endothelial cell of vascular tree	8 studies	19% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	26% ± 6%	Explore
endothelial cell of artery	7 studies	18% ± 2%	Explore
myeloid cell	7 studies	24% ± 10%	Explore
ciliated cell	7 studies	34% ± 14%	Explore
astrocyte	7 studies	32% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	27% ± 9%	Explore
T follicular helper cell	6 studies	20% ± 3%	Explore
plasma cell	5 studies	28% ± 11%	Explore
secretory cell	5 studies	26% ± 15%	Explore
leukocyte	5 studies	24% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	26% ± 6%	Explore
neuron	5 studies	27% ± 10%	Explore
glutamatergic neuron	5 studies	47% ± 22%	Explore
hematopoietic stem cell	5 studies	23% ± 6%	Explore
precursor B cell	5 studies	29% ± 11%	Explore
innate lymphoid cell	5 studies	19% ± 3%	Explore
oligodendrocyte precursor cell	5 studies	23% ± 6%	Explore
hematopoietic precursor cell	4 studies	34% ± 14%	Explore
exhausted T cell	4 studies	30% ± 6%	Explore
kidney loop of Henle epithelial cell	4 studies	23% ± 4%	Explore
epithelial cell of proximal tubule	4 studies	20% ± 2%	Explore
vein endothelial cell	4 studies	18% ± 1%	Explore
pro-B cell	4 studies	32% ± 4%	Explore
type I pneumocyte	4 studies	27% ± 9%	Explore
alveolar macrophage	4 studies	25% ± 4%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	36% ± 5%	Explore
GABAergic neuron	4 studies	45% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	33% ± 9%	Explore
transit amplifying cell	4 studies	26% ± 10%	Explore
interneuron	4 studies	39% ± 22%	Explore
oligodendrocyte	4 studies	25% ± 3%	Explore
plasmablast	3 studies	54% ± 8%	Explore
pancreatic A cell	3 studies	30% ± 6%	Explore
type B pancreatic cell	3 studies	30% ± 9%	Explore
mononuclear phagocyte	3 studies	36% ± 12%	Explore
neural crest cell	3 studies	19% ± 2%	Explore
erythroblast	3 studies	37% ± 23%	Explore
lymphocyte	3 studies	27% ± 8%	Explore
club cell	3 studies	25% ± 4%	Explore
enterocyte	3 studies	18% ± 1%	Explore
immature B cell	3 studies	19% ± 2%	Explore
germinal center B cell	3 studies	23% ± 2%	Explore
pancreatic ductal cell	3 studies	41% ± 14%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	37% ± 27%	Explore
enteroendocrine cell	3 studies	26% ± 10%	Explore
goblet cell	3 studies	27% ± 10%	Explore
intestinal crypt stem cell	3 studies	26% ± 4%	Explore
group 3 innate lymphoid cell	3 studies	28% ± 13%	Explore
T-helper 1 cell	3 studies	24% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	19% ± 4%	Explore
double negative thymocyte	3 studies	35% ± 13%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	19% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	25% ± 6%	Explore
lung	10 studies	27% ± 11%	Explore
intestine	7 studies	21% ± 10%	Explore
brain	7 studies	33% ± 16%	Explore
kidney	6 studies	20% ± 3%	Explore
lymph node	5 studies	22% ± 4%	Explore
uterus	4 studies	26% ± 12%	Explore
pancreas	3 studies	32% ± 8%	Explore
bone marrow	3 studies	18% ± 2%	Explore
eye	3 studies	21% ± 4%	Explore
liver	3 studies	35% ± 23%	Explore
breast	3 studies	19% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	2348.54	258 / 258	100%	47.86	230 / 230
bladder	100%	2692.00	21 / 21	100%	72.20	504 / 504
breast	100%	2869.33	459 / 459	100%	72.24	1118 / 1118
esophagus	100%	2578.49	1445 / 1445	100%	61.75	183 / 183
intestine	100%	2527.85	966 / 966	100%	63.85	527 / 527
kidney	100%	2118.63	89 / 89	100%	52.26	901 / 901
lung	100%	2144.49	578 / 578	100%	58.87	1155 / 1155
ovary	100%	2452.92	180 / 180	100%	70.89	430 / 430
prostate	100%	2140.44	245 / 245	100%	56.20	502 / 502
skin	100%	2587.55	1809 / 1809	100%	54.54	472 / 472
stomach	100%	2017.31	359 / 359	100%	62.12	286 / 286
thymus	100%	2205.26	653 / 653	100%	68.13	605 / 605
uterus	100%	2415.23	170 / 170	100%	73.32	459 / 459
brain	100%	1646.11	2633 / 2642	100%	50.76	705 / 705
liver	100%	1156.24	225 / 226	100%	40.69	406 / 406
pancreas	99%	1459.99	326 / 328	100%	58.52	178 / 178
adipose	100%	2987.94	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2900.28	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	62.05	80 / 80
lymph node	0%	0	0 / 0	100%	88.88	29 / 29
spleen	100%	2122.34	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	64.22	45 / 45
ureter	0%	0	0 / 0	100%	39.90	1 / 1
muscle	99%	1412.73	797 / 803	0%	0	0 / 0
heart	99%	1367.85	852 / 861	0%	0	0 / 0
peripheral blood	95%	1690.30	887 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0043248	Biological process	proteasome assembly
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0007094	Biological process	mitotic spindle assembly checkpoint signaling
GO_0051131	Biological process	chaperone-mediated protein complex assembly
GO_0101031	Cellular component	protein folding chaperone complex
GO_0005829	Cellular component	cytosol
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0060090	Molecular function	molecular adaptor activity

IV. Literature review

[source]

Gene name	PSMG2
Protein name	Proteasome assembly chaperone 2 Proteasome assembly chaperone 2 (PAC-2) (Hepatocellular carcinoma-susceptibility protein 3) (Tumor necrosis factor superfamily member 5-induced protein 1)
Synonyms	HCCA3 TNFSF5IP1 PAC2
Description	FUNCTION: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. . FUNCTION: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. . FUNCTION: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. .
Accessions	ENST00000317615.11 [Q969U7-1] ENST00000699169.1 ENST00000699168.1 A0A8V8TNA9 ENST00000699171.1 K7ENR6 ENST00000699165.1 A0A8V8TMU6 A0A8V8TP80 ENST00000699170.1 ENST00000586587.1 K7ER45 Q969U7 A0A8V8TMT6 ENST00000699164.1 [Q969U7-2] A0A8V8TPK9 A0A8V8TMV1 ENST00000585331.6 [Q969U7-2] ENST00000699166.1 ENST00000699172.1 A0A8V8TMU0 ENST00000590217.5

PSMG2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review