PSMD7 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	27 studies	27% ± 10%	Explore
endothelial cell	24 studies	27% ± 11%	Explore
fibroblast	24 studies	24% ± 10%	Explore
CD4-positive, alpha-beta T cell	23 studies	31% ± 17%	Explore
conventional dendritic cell	22 studies	28% ± 15%	Explore
macrophage	22 studies	26% ± 10%	Explore
pericyte	21 studies	22% ± 6%	Explore
T cell	20 studies	24% ± 8%	Explore
CD8-positive, alpha-beta T cell	20 studies	34% ± 16%	Explore
classical monocyte	20 studies	29% ± 13%	Explore
B cell	19 studies	25% ± 10%	Explore
smooth muscle cell	19 studies	25% ± 7%	Explore
regulatory T cell	19 studies	30% ± 11%	Explore
non-classical monocyte	18 studies	30% ± 14%	Explore
plasmacytoid dendritic cell	16 studies	32% ± 11%	Explore
monocyte	14 studies	25% ± 8%	Explore
memory B cell	14 studies	25% ± 8%	Explore
gamma-delta T cell	14 studies	29% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	29% ± 8%	Explore
basal cell	13 studies	29% ± 16%	Explore
naive B cell	13 studies	22% ± 6%	Explore
epithelial cell	13 studies	35% ± 18%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	25% ± 7%	Explore
connective tissue cell	12 studies	23% ± 7%	Explore
mast cell	11 studies	22% ± 6%	Explore
plasma cell	11 studies	38% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	30% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	30% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	29% ± 8%	Explore
mature NK T cell	11 studies	26% ± 6%	Explore
mucosal invariant T cell	10 studies	26% ± 5%	Explore
myeloid cell	10 studies	31% ± 12%	Explore
ciliated cell	10 studies	30% ± 16%	Explore
plasmablast	9 studies	48% ± 22%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	31% ± 10%	Explore
capillary endothelial cell	9 studies	21% ± 5%	Explore
endothelial cell of lymphatic vessel	8 studies	23% ± 7%	Explore
myofibroblast cell	8 studies	23% ± 5%	Explore
abnormal cell	8 studies	25% ± 8%	Explore
endothelial cell of artery	8 studies	23% ± 3%	Explore
vein endothelial cell	8 studies	19% ± 4%	Explore
dendritic cell	8 studies	38% ± 22%	Explore
secretory cell	7 studies	28% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	32% ± 13%	Explore
endothelial cell of vascular tree	7 studies	25% ± 6%	Explore
hematopoietic precursor cell	6 studies	42% ± 21%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	42% ± 17%	Explore
progenitor cell	6 studies	28% ± 14%	Explore
precursor B cell	6 studies	29% ± 9%	Explore
innate lymphoid cell	6 studies	23% ± 4%	Explore
neuron	6 studies	34% ± 13%	Explore
T follicular helper cell	6 studies	22% ± 3%	Explore
alveolar macrophage	5 studies	21% ± 3%	Explore
erythroblast	5 studies	36% ± 21%	Explore
hematopoietic stem cell	5 studies	26% ± 6%	Explore
pro-B cell	5 studies	29% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	38% ± 18%	Explore
deuterosomal cell	4 studies	20% ± 4%	Explore
pancreatic A cell	4 studies	53% ± 4%	Explore
type B pancreatic cell	4 studies	51% ± 11%	Explore
leukocyte	4 studies	28% ± 8%	Explore
mononuclear phagocyte	4 studies	28% ± 11%	Explore
exhausted T cell	4 studies	41% ± 13%	Explore
retinal ganglion cell	4 studies	65% ± 25%	Explore
club cell	4 studies	23% ± 7%	Explore
retina horizontal cell	4 studies	29% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	43% ± 10%	Explore
astrocyte	4 studies	17% ± 2%	Explore
glutamatergic neuron	4 studies	41% ± 18%	Explore
oligodendrocyte precursor cell	4 studies	22% ± 4%	Explore
goblet cell	4 studies	27% ± 9%	Explore
erythrocyte	4 studies	33% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	25% ± 6%	Explore
respiratory goblet cell	3 studies	33% ± 18%	Explore
mesothelial cell	3 studies	31% ± 17%	Explore
neural crest cell	3 studies	27% ± 2%	Explore
extravillous trophoblast	3 studies	36% ± 5%	Explore
placental villous trophoblast	3 studies	76% ± 1%	Explore
common myeloid progenitor	3 studies	31% ± 18%	Explore
lymphocyte	3 studies	31% ± 7%	Explore
immature B cell	3 studies	26% ± 6%	Explore
amacrine cell	3 studies	35% ± 11%	Explore
intermediate monocyte	3 studies	42% ± 23%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	25% ± 5%	Explore
muscle cell	3 studies	33% ± 13%	Explore
type I pneumocyte	3 studies	28% ± 7%	Explore
GABAergic neuron	3 studies	36% ± 5%	Explore
pancreatic ductal cell	3 studies	57% ± 9%	Explore
granulocyte	3 studies	22% ± 3%	Explore
granulocyte monocyte progenitor cell	3 studies	43% ± 23%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	44% ± 24%	Explore
enteroendocrine cell	3 studies	34% ± 11%	Explore
group 3 innate lymphoid cell	3 studies	31% ± 13%	Explore
transit amplifying cell	3 studies	21% ± 5%	Explore
keratinocyte	3 studies	19% ± 1%	Explore
T-helper 17 cell	3 studies	38% ± 25%	Explore
oligodendrocyte	3 studies	23% ± 5%	Explore
T-helper 1 cell	3 studies	35% ± 17%	Explore
double negative thymocyte	3 studies	45% ± 15%	Explore
hepatocyte	3 studies	32% ± 16%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	32% ± 11%	Explore
lung	13 studies	27% ± 13%	Explore
kidney	6 studies	20% ± 4%	Explore
intestine	6 studies	23% ± 10%	Explore
eye	6 studies	23% ± 8%	Explore
bone marrow	5 studies	23% ± 5%	Explore
lymph node	5 studies	23% ± 5%	Explore
brain	5 studies	33% ± 10%	Explore
pancreas	4 studies	48% ± 9%	Explore
placenta	3 studies	48% ± 9%	Explore
uterus	3 studies	30% ± 16%	Explore
breast	3 studies	19% ± 2%	Explore
liver	3 studies	40% ± 23%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2246.43	1445 / 1445	100%	42.76	183 / 183
stomach	100%	1526.19	358 / 359	100%	48.28	286 / 286
intestine	100%	2154.84	966 / 966	100%	52.82	525 / 527
lung	100%	1922.40	576 / 578	100%	43.13	1154 / 1155
bladder	100%	2295.48	21 / 21	99%	46.25	499 / 504
breast	100%	2022.82	459 / 459	99%	32.70	1103 / 1118
brain	99%	1463.86	2606 / 2642	100%	34.34	703 / 705
prostate	100%	1773.02	245 / 245	98%	38.56	493 / 502
uterus	100%	1645.56	170 / 170	98%	41.02	449 / 459
skin	100%	2943.30	1809 / 1809	97%	32.58	457 / 472
thymus	100%	1403.53	652 / 653	96%	21.46	582 / 605
ovary	100%	1171.89	180 / 180	95%	23.55	410 / 430
kidney	100%	1365.20	89 / 89	95%	22.65	856 / 901
pancreas	96%	871.21	316 / 328	98%	32.95	175 / 178
adrenal gland	100%	2430.59	258 / 258	90%	22.86	206 / 230
liver	96%	1142.02	218 / 226	92%	19.90	374 / 406
adipose	100%	2248.22	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2261.15	1335 / 1335	0%	0	0 / 0
muscle	100%	5143.37	803 / 803	0%	0	0 / 0
spleen	100%	1676.43	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	42.02	45 / 45
ureter	0%	0	0 / 0	100%	13.16	1 / 1
lymph node	0%	0	0 / 0	97%	36.71	28 / 29
heart	96%	2272.26	827 / 861	0%	0	0 / 0
peripheral blood	95%	1700.35	885 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	79%	12.62	63 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0043161	Biological process	proteasome-mediated ubiquitin-dependent protein catabolic process
GO_0000502	Cellular component	proteasome complex
GO_1904813	Cellular component	ficolin-1-rich granule lumen
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005576	Cellular component	extracellular region
GO_0005838	Cellular component	proteasome regulatory particle
GO_0016020	Cellular component	membrane
GO_0034774	Cellular component	secretory granule lumen
GO_0005634	Cellular component	nucleus
GO_0140492	Molecular function	metal-dependent deubiquitinase activity
GO_0042803	Molecular function	protein homodimerization activity
GO_0008233	Molecular function	peptidase activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	PSMD7
Protein name	Proteasome 26S subunit, non-ATPase 7 26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Synonyms	MOV34L
Description	FUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. .
Accessions	ENST00000568717.1 ENST00000219313.9 H3BTM8 H3BQV2 ENST00000568615.2 H3BNT7 P51665 ENST00000567958.5

PSMD7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review