PPP1R2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
CD8-positive, alpha-beta T cell	35 studies	35% ± 13%	Explore
B cell	34 studies	34% ± 10%	Explore
CD4-positive, alpha-beta T cell	34 studies	41% ± 14%	Explore
natural killer cell	32 studies	31% ± 9%	Explore
T cell	31 studies	35% ± 10%	Explore
regulatory T cell	26 studies	42% ± 13%	Explore
endothelial cell	25 studies	24% ± 7%	Explore
endothelial cell of lymphatic vessel	25 studies	54% ± 17%	Explore
macrophage	23 studies	20% ± 5%	Explore
conventional dendritic cell	21 studies	28% ± 14%	Explore
memory B cell	20 studies	33% ± 8%	Explore
plasmacytoid dendritic cell	18 studies	44% ± 14%	Explore
classical monocyte	18 studies	25% ± 11%	Explore
naive B cell	18 studies	34% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	43% ± 12%	Explore
mature NK T cell	17 studies	30% ± 9%	Explore
plasma cell	16 studies	33% ± 12%	Explore
gamma-delta T cell	16 studies	39% ± 11%	Explore
dendritic cell	15 studies	39% ± 21%	Explore
non-classical monocyte	15 studies	29% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	32% ± 9%	Explore
monocyte	14 studies	21% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	40% ± 12%	Explore
mucosal invariant T cell	14 studies	34% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	29% ± 7%	Explore
pericyte	13 studies	19% ± 5%	Explore
smooth muscle cell	12 studies	21% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	38% ± 12%	Explore
mast cell	11 studies	23% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	37% ± 14%	Explore
ciliated cell	11 studies	28% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	38% ± 13%	Explore
fibroblast	11 studies	23% ± 7%	Explore
endothelial cell of vascular tree	10 studies	22% ± 5%	Explore
plasmablast	9 studies	42% ± 23%	Explore
leukocyte	9 studies	29% ± 7%	Explore
epithelial cell	9 studies	36% ± 17%	Explore
innate lymphoid cell	8 studies	33% ± 9%	Explore
myofibroblast cell	8 studies	21% ± 3%	Explore
T follicular helper cell	8 studies	50% ± 7%	Explore
myeloid cell	8 studies	26% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	31% ± 7%	Explore
capillary endothelial cell	7 studies	20% ± 4%	Explore
endothelial cell of artery	7 studies	21% ± 7%	Explore
connective tissue cell	7 studies	20% ± 4%	Explore
basal cell	7 studies	27% ± 11%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	41% ± 12%	Explore
precursor B cell	6 studies	49% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	44% ± 14%	Explore
abnormal cell	6 studies	26% ± 9%	Explore
CD4-positive helper T cell	5 studies	35% ± 11%	Explore
exhausted T cell	5 studies	43% ± 12%	Explore
glutamatergic neuron	5 studies	39% ± 18%	Explore
lymphocyte	5 studies	38% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	28% ± 6%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	33% ± 12%	Explore
pancreatic A cell	4 studies	28% ± 5%	Explore
mononuclear phagocyte	4 studies	28% ± 8%	Explore
pro-B cell	4 studies	29% ± 3%	Explore
immature B cell	4 studies	48% ± 9%	Explore
retina horizontal cell	4 studies	28% ± 8%	Explore
retinal rod cell	4 studies	19% ± 5%	Explore
alveolar macrophage	4 studies	19% ± 4%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	25% ± 3%	Explore
vein endothelial cell	4 studies	20% ± 5%	Explore
granulocyte	4 studies	22% ± 6%	Explore
GABAergic neuron	4 studies	38% ± 14%	Explore
T-helper 17 cell	4 studies	33% ± 11%	Explore
interneuron	4 studies	30% ± 17%	Explore
neuron	4 studies	32% ± 12%	Explore
double negative thymocyte	4 studies	44% ± 11%	Explore
secretory cell	4 studies	27% ± 8%	Explore
deuterosomal cell	3 studies	27% ± 1%	Explore
type B pancreatic cell	3 studies	39% ± 1%	Explore
kidney loop of Henle epithelial cell	3 studies	16% ± 0%	Explore
IgA plasma cell	3 studies	25% ± 8%	Explore
retinal ganglion cell	3 studies	51% ± 25%	Explore
amacrine cell	3 studies	39% ± 7%	Explore
retinal cone cell	3 studies	35% ± 10%	Explore
intraepithelial lymphocyte	3 studies	29% ± 11%	Explore
Mueller cell	3 studies	18% ± 2%	Explore
germinal center B cell	3 studies	27% ± 5%	Explore
intermediate monocyte	3 studies	39% ± 24%	Explore
astrocyte	3 studies	18% ± 1%	Explore
enteroendocrine cell	3 studies	27% ± 12%	Explore
intestinal crypt stem cell	3 studies	20% ± 1%	Explore
group 3 innate lymphoid cell	3 studies	47% ± 11%	Explore
T-helper 1 cell	3 studies	44% ± 11%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	48% ± 7%	Explore
erythrocyte	3 studies	27% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	35% ± 10%	Explore
lung	14 studies	25% ± 9%	Explore
intestine	7 studies	25% ± 7%	Explore
eye	6 studies	21% ± 6%	Explore
brain	6 studies	30% ± 13%	Explore
uterus	4 studies	27% ± 9%	Explore
lymph node	4 studies	34% ± 11%	Explore
breast	4 studies	24% ± 4%	Explore
liver	4 studies	28% ± 5%	Explore
pancreas	3 studies	33% ± 3%	Explore
kidney	3 studies	31% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	3001.67	459 / 459	100%	51.03	1118 / 1118
esophagus	100%	3559.38	1445 / 1445	100%	47.81	183 / 183
lung	100%	3093.64	578 / 578	100%	48.91	1155 / 1155
ovary	100%	2240.62	180 / 180	100%	38.31	430 / 430
prostate	100%	2942.80	245 / 245	100%	39.28	502 / 502
uterus	100%	3063.90	170 / 170	100%	41.94	459 / 459
thymus	100%	3358.65	653 / 653	100%	58.82	603 / 605
brain	100%	2732.55	2633 / 2642	100%	36.55	705 / 705
stomach	100%	2122.49	359 / 359	100%	43.94	285 / 286
intestine	100%	3519.63	966 / 966	100%	40.46	525 / 527
bladder	100%	3041.05	21 / 21	100%	38.08	502 / 504
kidney	100%	2347.36	89 / 89	99%	31.04	893 / 901
adrenal gland	100%	2183.81	258 / 258	97%	24.70	222 / 230
pancreas	95%	1128.77	313 / 328	99%	41.07	176 / 178
skin	100%	2687.12	1808 / 1809	93%	29.61	440 / 472
liver	92%	821.96	207 / 226	92%	15.95	373 / 406
adipose	100%	3025.68	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3570.88	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	50.36	29 / 29
muscle	100%	6089.59	803 / 803	0%	0	0 / 0
spleen	100%	2965.70	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	46.00	45 / 45
ureter	0%	0	0 / 0	100%	12.19	1 / 1
heart	98%	2072.58	847 / 861	0%	0	0 / 0
peripheral blood	98%	2862.15	912 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	55%	7.74	44 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0009966	Biological process	regulation of signal transduction
GO_0006091	Biological process	generation of precursor metabolites and energy
GO_0005977	Biological process	glycogen metabolic process
GO_0043666	Biological process	regulation of phosphoprotein phosphatase activity
GO_0004864	Molecular function	protein phosphatase inhibitor activity
GO_0005515	Molecular function	protein binding
GO_0004865	Molecular function	protein serine/threonine phosphatase inhibitor activity
GO_0140678	Molecular function	molecular function inhibitor activity

IV. Literature review

[source]

Gene name	PPP1R2
Protein name	PPP1R2 protein Protein phosphatase inhibitor 2 (IPP-2) Protein phosphatase 1 regulatory inhibitor subunit 2
Synonyms	IPP2
Description	FUNCTION: Inhibitor of protein-phosphatase 1. FUNCTION: Inhibitor of protein-phosphatase 1. . FUNCTION: Inhibitor of protein-phosphatase 1. . FUNCTION: Inhibitor of protein-phosphatase 1. . FUNCTION: Inhibitor of protein-phosphatase 1. .
Accessions	P41236 H7C416 ENST00000438848.5 ENST00000618156.5 E7EMN6 ENST00000625807.1 E7EUI7 Q6NXS2 ENST00000418939.1 ENST00000413183.3

PPP1R2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review