NDUFC2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009060Biological processaerobic respiration
GO_0006120Biological processmitochondrial electron transport, NADH to ubiquinone
GO_0042776Biological processproton motive force-driven mitochondrial ATP synthesis
GO_0055085Biological processtransmembrane transport
GO_0032981Biological processmitochondrial respiratory chain complex I assembly
GO_0005743Cellular componentmitochondrial inner membrane
GO_0035577Cellular componentazurophil granule membrane
GO_0045271Cellular componentrespiratory chain complex I
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005739Cellular componentmitochondrion
GO_0008137Molecular functionNADH dehydrogenase (ubiquinone) activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNDUFC2
Protein nameNADH:ubiquinone oxidoreductase subunit C2
NADH dehydrogenase [ubiquinone] 1 subunit C2 (Complex I-B14.5b) (CI-B14.5b) (Human lung cancer oncogene 1 protein) (HLC-1) (NADH-ubiquinone oxidoreductase subunit B14.5b)
NADH dehydrogenase [ubiquinone] 1 subunit C2
SynonymsHLC1
DescriptionFUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis but required for the complex assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. .

FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. .

AccessionsE9PM14
ENST00000527806.1 [O95298-3]
ENST00000534029.5
ENST00000525085.1 [O95298-2]
O95298
ENST00000528164.1
ENST00000281031.5 [O95298-1]
E9PRJ5