MT-ND6 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	32 studies	38% ± 22%	Explore
natural killer cell	28 studies	37% ± 18%	Explore
CD4-positive, alpha-beta T cell	26 studies	37% ± 18%	Explore
T cell	25 studies	38% ± 14%	Explore
CD8-positive, alpha-beta T cell	25 studies	37% ± 16%	Explore
macrophage	22 studies	28% ± 11%	Explore
regulatory T cell	21 studies	41% ± 13%	Explore
endothelial cell	20 studies	30% ± 12%	Explore
memory B cell	19 studies	40% ± 14%	Explore
conventional dendritic cell	19 studies	32% ± 13%	Explore
classical monocyte	18 studies	26% ± 8%	Explore
non-classical monocyte	18 studies	33% ± 11%	Explore
gamma-delta T cell	18 studies	44% ± 14%	Explore
plasma cell	17 studies	43% ± 19%	Explore
naive B cell	17 studies	39% ± 15%	Explore
plasmacytoid dendritic cell	16 studies	41% ± 13%	Explore
dendritic cell	15 studies	40% ± 21%	Explore
mature NK T cell	14 studies	31% ± 12%	Explore
monocyte	13 studies	26% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	44% ± 15%	Explore
ciliated cell	13 studies	47% ± 18%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	42% ± 20%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	48% ± 19%	Explore
mucosal invariant T cell	12 studies	49% ± 15%	Explore
pericyte	11 studies	30% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	37% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	43% ± 13%	Explore
basal cell	11 studies	42% ± 21%	Explore
epithelial cell	11 studies	43% ± 20%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	39% ± 10%	Explore
smooth muscle cell	10 studies	35% ± 24%	Explore
plasmablast	10 studies	52% ± 18%	Explore
endothelial cell of lymphatic vessel	9 studies	25% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	36% ± 7%	Explore
fibroblast	8 studies	35% ± 18%	Explore
endothelial cell of artery	8 studies	31% ± 12%	Explore
connective tissue cell	8 studies	26% ± 10%	Explore
vein endothelial cell	8 studies	25% ± 11%	Explore
club cell	7 studies	46% ± 24%	Explore
respiratory goblet cell	7 studies	57% ± 18%	Explore
secretory cell	7 studies	33% ± 9%	Explore
platelet	7 studies	27% ± 10%	Explore
type II pneumocyte	7 studies	34% ± 26%	Explore
innate lymphoid cell	7 studies	34% ± 10%	Explore
mast cell	6 studies	37% ± 12%	Explore
type I pneumocyte	6 studies	38% ± 25%	Explore
erythrocyte	6 studies	32% ± 10%	Explore
capillary endothelial cell	6 studies	37% ± 17%	Explore
goblet cell	6 studies	26% ± 8%	Explore
myeloid cell	6 studies	48% ± 21%	Explore
alveolar macrophage	6 studies	31% ± 16%	Explore
IgA plasma cell	6 studies	35% ± 9%	Explore
IgG plasma cell	6 studies	32% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	39% ± 10%	Explore
ionocyte	5 studies	54% ± 9%	Explore
abnormal cell	5 studies	46% ± 7%	Explore
hematopoietic stem cell	5 studies	37% ± 9%	Explore
CD4-positive helper T cell	5 studies	29% ± 11%	Explore
T follicular helper cell	5 studies	32% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	47% ± 5%	Explore
deuterosomal cell	4 studies	42% ± 5%	Explore
exhausted T cell	4 studies	46% ± 15%	Explore
epithelial cell of proximal tubule	4 studies	30% ± 11%	Explore
renal alpha-intercalated cell	4 studies	40% ± 6%	Explore
enterocyte	4 studies	23% ± 8%	Explore
pro-B cell	4 studies	30% ± 18%	Explore
brush cell	4 studies	41% ± 19%	Explore
hepatocyte	4 studies	47% ± 26%	Explore
endothelial cell of vascular tree	4 studies	39% ± 35%	Explore
T-helper 17 cell	4 studies	31% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	37% ± 5%	Explore
hematopoietic precursor cell	3 studies	21% ± 3%	Explore
duct epithelial cell	3 studies	25% ± 10%	Explore
endothelial cell of sinusoid	3 studies	38% ± 8%	Explore
GABAergic neuron	3 studies	53% ± 28%	Explore
transit amplifying cell	3 studies	32% ± 8%	Explore
retinal ganglion cell	3 studies	48% ± 20%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	54% ± 10%	Explore
kidney loop of Henle epithelial cell	3 studies	49% ± 10%	Explore
renal principal cell	3 studies	48% ± 10%	Explore
common myeloid progenitor	3 studies	38% ± 23%	Explore
erythroblast	3 studies	48% ± 14%	Explore
lymphocyte	3 studies	42% ± 9%	Explore
megakaryocyte	3 studies	31% ± 10%	Explore
myofibroblast cell	3 studies	21% ± 2%	Explore
inflammatory macrophage	3 studies	35% ± 15%	Explore
intermediate monocyte	3 studies	29% ± 6%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	46% ± 25%	Explore
enteroendocrine cell	3 studies	30% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	40% ± 11%	Explore
T-helper 1 cell	3 studies	39% ± 15%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	30% ± 3%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	33% ± 4%	Explore
double negative thymocyte	3 studies	45% ± 10%	Explore
double-positive, alpha-beta thymocyte	3 studies	51% ± 10%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	54% ± 15%	Explore
neuron	3 studies	26% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	43% ± 21%	Explore
lung	14 studies	33% ± 22%	Explore
liver	6 studies	34% ± 16%	Explore
bone marrow	4 studies	27% ± 17%	Explore
intestine	4 studies	25% ± 5%	Explore
brain	3 studies	48% ± 30%	Explore
kidney	3 studies	34% ± 5%	Explore
lymph node	3 studies	45% ± 14%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	99%	188243.51	2615 / 2642	99%	11993.25	700 / 705
kidney	93%	147232.56	83 / 89	98%	10701.65	879 / 901
liver	99%	118582.83	223 / 226	92%	5919.70	373 / 406
adrenal gland	96%	120663.84	247 / 258	94%	6887.82	217 / 230
skin	98%	109339.35	1769 / 1809	92%	5853.74	434 / 472
stomach	98%	148692.71	352 / 359	90%	3841.32	257 / 286
breast	83%	60880.51	379 / 459	94%	5329.00	1047 / 1118
esophagus	83%	100775.45	1200 / 1445	89%	3562.89	162 / 183
bladder	86%	103244.33	18 / 21	85%	5060.46	426 / 504
prostate	76%	49163.88	186 / 245	93%	5516.79	466 / 502
intestine	84%	110187.24	811 / 966	83%	3938.82	436 / 527
pancreas	60%	35890.25	198 / 328	96%	6529.79	171 / 178
lung	69%	93716.40	400 / 578	79%	4066.88	918 / 1155
ovary	49%	37990.59	88 / 180	98%	5687.61	423 / 430
thymus	51%	48908.50	333 / 653	95%	10421.79	573 / 605
uterus	60%	50015.05	102 / 170	85%	4815.58	388 / 459
eye	0%	0	0 / 0	100%	11391.62	80 / 80
ureter	0%	0	0 / 0	100%	10508.33	1 / 1
heart	100%	278863.70	859 / 861	0%	0	0 / 0
muscle	100%	203508.85	799 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	89%	3688.74	40 / 45
spleen	79%	81501.02	191 / 241	0%	0	0 / 0
adipose	79%	80891.74	949 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	76%	2193.84	22 / 29
blood vessel	71%	72084.83	943 / 1335	0%	0	0 / 0
peripheral blood	35%	22988.01	323 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0042542	Biological process	response to hydrogen peroxide
GO_0042220	Biological process	response to cocaine
GO_0009060	Biological process	aerobic respiration
GO_0006120	Biological process	mitochondrial electron transport, NADH to ubiquinone
GO_0042776	Biological process	proton motive force-driven mitochondrial ATP synthesis
GO_0035094	Biological process	response to nicotine
GO_0055085	Biological process	transmembrane transport
GO_0032981	Biological process	mitochondrial respiratory chain complex I assembly
GO_0045271	Cellular component	respiratory chain complex I
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005739	Cellular component	mitochondrion
GO_0008137	Molecular function	NADH dehydrogenase (ubiquinone) activity

Gene name	MT-ND6
Protein name	NADH-ubiquinone oxidoreductase chain 6 (EC 7.1.1.2) (NADH dehydrogenase subunit 6)
Synonyms	MTND6 ND6 NADH6
Description	FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor . Essential for the catalytic activity and assembly of complex I . .
Accessions	ENST00000361681.2 P03923

MT-ND6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review