MIEN1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	28 studies	28% ± 8%	Explore
CD8-positive, alpha-beta T cell	18 studies	26% ± 8%	Explore
non-classical monocyte	17 studies	32% ± 14%	Explore
B cell	16 studies	25% ± 8%	Explore
macrophage	16 studies	23% ± 7%	Explore
classical monocyte	16 studies	27% ± 10%	Explore
regulatory T cell	16 studies	24% ± 7%	Explore
CD4-positive, alpha-beta T cell	15 studies	24% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	32% ± 10%	Explore
ciliated cell	13 studies	35% ± 17%	Explore
gamma-delta T cell	13 studies	27% ± 12%	Explore
memory B cell	12 studies	20% ± 3%	Explore
mature NK T cell	12 studies	26% ± 7%	Explore
naive B cell	12 studies	20% ± 4%	Explore
epithelial cell	12 studies	39% ± 19%	Explore
basal cell	11 studies	31% ± 17%	Explore
monocyte	11 studies	21% ± 6%	Explore
endothelial cell	11 studies	27% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	27% ± 4%	Explore
T cell	9 studies	24% ± 5%	Explore
plasmacytoid dendritic cell	9 studies	27% ± 10%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	22% ± 6%	Explore
goblet cell	8 studies	25% ± 10%	Explore
abnormal cell	8 studies	30% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	28% ± 12%	Explore
secretory cell	7 studies	32% ± 18%	Explore
mucosal invariant T cell	7 studies	19% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	26% ± 7%	Explore
club cell	6 studies	27% ± 7%	Explore
respiratory goblet cell	6 studies	28% ± 18%	Explore
endothelial cell of artery	6 studies	17% ± 2%	Explore
conventional dendritic cell	5 studies	38% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	26% ± 5%	Explore
kidney loop of Henle epithelial cell	5 studies	24% ± 4%	Explore
renal alpha-intercalated cell	5 studies	39% ± 6%	Explore
enteroendocrine cell	5 studies	35% ± 18%	Explore
smooth muscle cell	5 studies	19% ± 2%	Explore
precursor B cell	5 studies	30% ± 9%	Explore
myeloid cell	5 studies	25% ± 8%	Explore
plasma cell	5 studies	29% ± 9%	Explore
brush cell	5 studies	32% ± 13%	Explore
enterocyte	5 studies	22% ± 5%	Explore
endothelial cell of lymphatic vessel	5 studies	27% ± 8%	Explore
fibroblast	5 studies	24% ± 11%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	30% ± 7%	Explore
mast cell	5 studies	20% ± 5%	Explore
ionocyte	4 studies	34% ± 10%	Explore
pancreatic A cell	4 studies	48% ± 13%	Explore
exhausted T cell	4 studies	36% ± 5%	Explore
epithelial cell of proximal tubule	4 studies	21% ± 3%	Explore
neuron	4 studies	28% ± 17%	Explore
capillary endothelial cell	4 studies	17% ± 1%	Explore
immature B cell	4 studies	29% ± 10%	Explore
type II pneumocyte	4 studies	36% ± 16%	Explore
T follicular helper cell	4 studies	21% ± 3%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	26% ± 9%	Explore
endothelial cell of vascular tree	4 studies	20% ± 2%	Explore
intermediate monocyte	4 studies	39% ± 13%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	28% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	27% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	22% ± 3%	Explore
hematopoietic precursor cell	3 studies	27% ± 7%	Explore
plasmablast	3 studies	52% ± 4%	Explore
squamous epithelial cell	3 studies	49% ± 20%	Explore
pancreatic D cell	3 studies	44% ± 20%	Explore
type B pancreatic cell	3 studies	55% ± 2%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	20% ± 3%	Explore
retinal ganglion cell	3 studies	57% ± 25%	Explore
pericyte	3 studies	19% ± 1%	Explore
neuroendocrine cell	3 studies	56% ± 24%	Explore
pro-B cell	3 studies	24% ± 3%	Explore
type I pneumocyte	3 studies	30% ± 11%	Explore
amacrine cell	3 studies	33% ± 12%	Explore
retina horizontal cell	3 studies	33% ± 15%	Explore
serous secreting cell	3 studies	28% ± 1%	Explore
intraepithelial lymphocyte	3 studies	27% ± 10%	Explore
Mueller cell	3 studies	23% ± 6%	Explore
erythroblast	3 studies	36% ± 21%	Explore
germinal center B cell	3 studies	23% ± 5%	Explore
luminal cell of prostate epithelium	3 studies	31% ± 11%	Explore
dendritic cell	3 studies	41% ± 18%	Explore
pancreatic ductal cell	3 studies	50% ± 18%	Explore
T-helper 17 cell	3 studies	24% ± 9%	Explore
double negative thymocyte	3 studies	33% ± 16%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	25% ± 8%	Explore
lung	11 studies	29% ± 15%	Explore
kidney	5 studies	21% ± 4%	Explore
intestine	5 studies	21% ± 6%	Explore
liver	4 studies	29% ± 21%	Explore
lymph node	4 studies	24% ± 9%	Explore
brain	4 studies	21% ± 4%	Explore
pancreas	3 studies	53% ± 3%	Explore
eye	3 studies	21% ± 7%	Explore
breast	3 studies	18% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1337.49	1445 / 1445	100%	143.86	183 / 183
liver	100%	1196.49	226 / 226	100%	44.05	406 / 406
ovary	100%	656.67	180 / 180	100%	80.92	430 / 430
pancreas	100%	935.53	328 / 328	100%	51.76	178 / 178
skin	100%	1237.03	1809 / 1809	100%	45.79	472 / 472
thymus	100%	1544.29	653 / 653	100%	55.48	605 / 605
uterus	100%	965.78	170 / 170	100%	89.57	459 / 459
brain	100%	1866.87	2642 / 2642	100%	46.50	704 / 705
intestine	100%	1401.72	966 / 966	100%	109.86	526 / 527
bladder	100%	1216.71	21 / 21	100%	87.66	503 / 504
kidney	100%	2007.38	89 / 89	100%	43.17	898 / 901
prostate	100%	2082.13	245 / 245	100%	80.11	500 / 502
adrenal gland	100%	1321.72	258 / 258	100%	37.96	229 / 230
stomach	100%	1422.02	359 / 359	99%	120.19	284 / 286
breast	100%	1204.63	459 / 459	99%	115.32	1109 / 1118
lung	100%	1153.21	576 / 578	99%	76.80	1148 / 1155
adipose	100%	1033.09	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	46.59	80 / 80
lymph node	0%	0	0 / 0	100%	68.16	29 / 29
spleen	100%	1370.00	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	81.00	45 / 45
ureter	0%	0	0 / 0	100%	66.29	1 / 1
heart	100%	1255.44	859 / 861	0%	0	0 / 0
blood vessel	100%	1099.02	1330 / 1335	0%	0	0 / 0
peripheral blood	99%	1218.59	919 / 929	0%	0	0 / 0
muscle	99%	1004.28	794 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006915	Biological process	apoptotic process
GO_0051491	Biological process	positive regulation of filopodium assembly
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0030335	Biological process	positive regulation of cell migration
GO_0009898	Cellular component	cytoplasmic side of plasma membrane
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	MIEN1
Protein name	Migration and invasion enhancer 1 (HBV X-transactivated gene 4 protein) (HBV XAg-transactivated protein 4) (Protein C35) Migration and invasion enhancer 1
Synonyms	RDX12 XTP4 C17orf37
Description	FUNCTION: Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. .
Accessions	J3KTI2 ENST00000394231.8 ENST00000577810.1 Q9BRT3

MIEN1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review