LMAN2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	35 studies	33% ± 10%	Explore
fibroblast	29 studies	32% ± 13%	Explore
endothelial cell	27 studies	29% ± 12%	Explore
CD4-positive, alpha-beta T cell	27 studies	27% ± 11%	Explore
CD8-positive, alpha-beta T cell	27 studies	30% ± 12%	Explore
T cell	26 studies	26% ± 7%	Explore
macrophage	26 studies	30% ± 12%	Explore
plasma cell	24 studies	55% ± 24%	Explore
B cell	22 studies	23% ± 7%	Explore
non-classical monocyte	20 studies	31% ± 14%	Explore
classical monocyte	20 studies	29% ± 12%	Explore
conventional dendritic cell	19 studies	29% ± 15%	Explore
regulatory T cell	19 studies	31% ± 8%	Explore
epithelial cell	18 studies	40% ± 22%	Explore
monocyte	17 studies	26% ± 9%	Explore
mature NK T cell	17 studies	31% ± 9%	Explore
plasmacytoid dendritic cell	17 studies	36% ± 12%	Explore
pericyte	17 studies	25% ± 9%	Explore
gamma-delta T cell	17 studies	32% ± 11%	Explore
ciliated cell	16 studies	37% ± 16%	Explore
basal cell	15 studies	36% ± 19%	Explore
mast cell	14 studies	27% ± 13%	Explore
endothelial cell of lymphatic vessel	14 studies	31% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	35% ± 9%	Explore
connective tissue cell	14 studies	31% ± 11%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	22% ± 5%	Explore
smooth muscle cell	13 studies	23% ± 6%	Explore
plasmablast	12 studies	61% ± 22%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	34% ± 9%	Explore
myofibroblast cell	12 studies	28% ± 9%	Explore
naive B cell	11 studies	20% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	28% ± 6%	Explore
capillary endothelial cell	11 studies	24% ± 7%	Explore
dendritic cell	11 studies	37% ± 22%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	30% ± 10%	Explore
secretory cell	10 studies	30% ± 13%	Explore
abnormal cell	10 studies	34% ± 18%	Explore
endothelial cell of artery	10 studies	24% ± 7%	Explore
vein endothelial cell	10 studies	26% ± 10%	Explore
mucosal invariant T cell	10 studies	31% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	30% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	29% ± 10%	Explore
IgG plasma cell	9 studies	40% ± 17%	Explore
myeloid cell	9 studies	34% ± 12%	Explore
memory B cell	9 studies	22% ± 4%	Explore
goblet cell	8 studies	33% ± 14%	Explore
IgA plasma cell	8 studies	41% ± 18%	Explore
endothelial cell of vascular tree	8 studies	25% ± 6%	Explore
club cell	7 studies	36% ± 14%	Explore
alveolar macrophage	6 studies	23% ± 4%	Explore
type I pneumocyte	6 studies	30% ± 12%	Explore
respiratory goblet cell	6 studies	32% ± 25%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	41% ± 13%	Explore
leukocyte	6 studies	27% ± 8%	Explore
progenitor cell	6 studies	31% ± 8%	Explore
enterocyte	6 studies	24% ± 5%	Explore
mesothelial cell	6 studies	36% ± 17%	Explore
innate lymphoid cell	6 studies	30% ± 7%	Explore
type II pneumocyte	6 studies	33% ± 16%	Explore
T follicular helper cell	6 studies	26% ± 2%	Explore
hematopoietic precursor cell	5 studies	37% ± 15%	Explore
ionocyte	5 studies	25% ± 7%	Explore
transit amplifying cell	5 studies	22% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	36% ± 15%	Explore
pancreatic A cell	4 studies	40% ± 17%	Explore
mononuclear phagocyte	4 studies	35% ± 17%	Explore
exhausted T cell	4 studies	43% ± 8%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	41% ± 7%	Explore
epithelial cell of proximal tubule	4 studies	29% ± 12%	Explore
enteroendocrine cell	4 studies	32% ± 10%	Explore
adventitial cell	4 studies	37% ± 11%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	49% ± 11%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	35% ± 8%	Explore
neuron	4 studies	25% ± 10%	Explore
T-helper 17 cell	4 studies	35% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	31% ± 6%	Explore
duct epithelial cell	3 studies	27% ± 2%	Explore
type B pancreatic cell	3 studies	46% ± 11%	Explore
glomerular endothelial cell	3 studies	22% ± 2%	Explore
intestinal crypt stem cell	3 studies	26% ± 8%	Explore
neural crest cell	3 studies	21% ± 2%	Explore
kidney loop of Henle epithelial cell	3 studies	31% ± 8%	Explore
extravillous trophoblast	3 studies	68% ± 13%	Explore
placental villous trophoblast	3 studies	68% ± 17%	Explore
common myeloid progenitor	3 studies	34% ± 18%	Explore
hematopoietic stem cell	3 studies	24% ± 6%	Explore
lymphocyte	3 studies	34% ± 11%	Explore
brush cell	3 studies	28% ± 6%	Explore
immature B cell	3 studies	22% ± 4%	Explore
precursor B cell	3 studies	32% ± 8%	Explore
pro-B cell	3 studies	24% ± 5%	Explore
mucus secreting cell	3 studies	32% ± 8%	Explore
serous secreting cell	3 studies	33% ± 11%	Explore
intraepithelial lymphocyte	3 studies	34% ± 10%	Explore
erythroblast	3 studies	30% ± 21%	Explore
intermediate monocyte	3 studies	43% ± 18%	Explore
CD4-positive helper T cell	3 studies	22% ± 6%	Explore
myoepithelial cell	3 studies	29% ± 10%	Explore
IgM plasma cell	3 studies	45% ± 12%	Explore
pancreatic ductal cell	3 studies	55% ± 12%	Explore
oligodendrocyte precursor cell	3 studies	20% ± 5%	Explore
granulocyte monocyte progenitor cell	3 studies	46% ± 21%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	38% ± 25%	Explore
group 3 innate lymphoid cell	3 studies	37% ± 11%	Explore
T-helper 1 cell	3 studies	38% ± 12%	Explore
double negative thymocyte	3 studies	42% ± 10%	Explore
hepatocyte	3 studies	43% ± 24%	Explore
luminal cell of prostate epithelium	3 studies	21% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	32% ± 11%	Explore
peripheral blood	15 studies	30% ± 7%	Explore
intestine	11 studies	26% ± 11%	Explore
kidney	7 studies	28% ± 8%	Explore
liver	6 studies	29% ± 14%	Explore
lymph node	5 studies	29% ± 14%	Explore
brain	5 studies	23% ± 5%	Explore
pancreas	4 studies	41% ± 17%	Explore
bone marrow	4 studies	22% ± 4%	Explore
uterus	4 studies	40% ± 16%	Explore
breast	4 studies	24% ± 4%	Explore
placenta	3 studies	54% ± 20%	Explore
eye	3 studies	23% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	8837.20	226 / 226	100%	446.87	406 / 406
ovary	100%	5269.66	180 / 180	100%	228.69	430 / 430
pancreas	100%	6575.44	328 / 328	100%	287.68	178 / 178
uterus	100%	5665.71	170 / 170	100%	320.02	459 / 459
thymus	100%	8146.63	653 / 653	100%	370.09	604 / 605
skin	100%	6400.69	1808 / 1809	100%	302.85	471 / 472
kidney	100%	6211.01	89 / 89	100%	316.87	898 / 901
prostate	100%	5569.83	245 / 245	100%	325.56	500 / 502
intestine	100%	5165.68	966 / 966	99%	321.03	524 / 527
esophagus	100%	6003.43	1444 / 1445	99%	146.89	182 / 183
stomach	100%	4999.85	359 / 359	99%	248.22	284 / 286
breast	100%	5374.50	459 / 459	99%	304.89	1110 / 1118
lung	100%	6522.08	577 / 578	99%	261.97	1148 / 1155
bladder	100%	5371.95	21 / 21	99%	301.88	499 / 504
adrenal gland	100%	5932.54	258 / 258	98%	195.26	225 / 230
brain	97%	2171.88	2564 / 2642	100%	164.82	704 / 705
adipose	100%	4857.59	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	199.47	80 / 80
lymph node	0%	0	0 / 0	100%	320.10	29 / 29
spleen	100%	6851.49	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	291.22	45 / 45
ureter	0%	0	0 / 0	100%	203.40	1 / 1
blood vessel	100%	4871.05	1331 / 1335	0%	0	0 / 0
peripheral blood	99%	7990.02	924 / 929	0%	0	0 / 0
heart	98%	3668.12	846 / 861	0%	0	0 / 0
muscle	96%	2179.18	772 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0050766	Biological process	positive regulation of phagocytosis
GO_0006890	Biological process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO_0015031	Biological process	protein transport
GO_0006888	Biological process	endoplasmic reticulum to Golgi vesicle-mediated transport
GO_0005615	Cellular component	extracellular space
GO_0005886	Cellular component	plasma membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005794	Cellular component	Golgi apparatus
GO_0033116	Cellular component	endoplasmic reticulum-Golgi intermediate compartment membrane
GO_0009986	Cellular component	cell surface
GO_0000139	Cellular component	Golgi membrane
GO_0005793	Cellular component	endoplasmic reticulum-Golgi intermediate compartment
GO_0030134	Cellular component	COPII-coated ER to Golgi transport vesicle
GO_0005537	Molecular function	D-mannose binding
GO_0031072	Molecular function	heat shock protein binding
GO_0030246	Molecular function	carbohydrate binding
GO_0046872	Molecular function	metal ion binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	LMAN2
Protein name	Epididymis secretory sperm binding protein (Lectin, mannose-binding 2, isoform CRA_a) Vesicular integral-membrane protein VIP36 (Glycoprotein GP36b) (Lectin mannose-binding 2) (Vesicular integral-membrane protein 36) (VIP36) Lectin, mannose binding 2
Synonyms	C5orf8 hCG_1981210
Description	FUNCTION: Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity). .
Accessions	ENST00000694905.1 A0A384NPY7 D6RIU4 ENST00000513877.1 A0A8Q3WK65 D6RBH1 Q12907 D6RBV2 ENST00000515209.5 ENST00000303127.12 D6RDX1 ENST00000514458.5 ENST00000502560.5

LMAN2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review