KRTCAP2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	32 studies	36% ± 14%	Explore
fibroblast	30 studies	37% ± 17%	Explore
CD8-positive, alpha-beta T cell	30 studies	43% ± 17%	Explore
B cell	28 studies	33% ± 15%	Explore
CD4-positive, alpha-beta T cell	26 studies	43% ± 17%	Explore
T cell	24 studies	34% ± 11%	Explore
endothelial cell	24 studies	42% ± 17%	Explore
macrophage	24 studies	41% ± 11%	Explore
conventional dendritic cell	23 studies	40% ± 15%	Explore
regulatory T cell	23 studies	47% ± 15%	Explore
pericyte	23 studies	33% ± 10%	Explore
classical monocyte	22 studies	40% ± 13%	Explore
plasma cell	21 studies	65% ± 20%	Explore
plasmacytoid dendritic cell	21 studies	54% ± 18%	Explore
mature NK T cell	18 studies	41% ± 14%	Explore
non-classical monocyte	18 studies	42% ± 13%	Explore
smooth muscle cell	18 studies	34% ± 13%	Explore
memory B cell	17 studies	36% ± 11%	Explore
gamma-delta T cell	16 studies	42% ± 12%	Explore
endothelial cell of lymphatic vessel	15 studies	55% ± 17%	Explore
naive B cell	15 studies	31% ± 9%	Explore
mast cell	14 studies	32% ± 8%	Explore
ciliated cell	14 studies	45% ± 21%	Explore
epithelial cell	14 studies	43% ± 23%	Explore
monocyte	14 studies	33% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	38% ± 13%	Explore
mucosal invariant T cell	13 studies	49% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	40% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	44% ± 14%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	48% ± 11%	Explore
basal cell	12 studies	38% ± 19%	Explore
capillary endothelial cell	12 studies	40% ± 14%	Explore
myofibroblast cell	12 studies	38% ± 14%	Explore
connective tissue cell	12 studies	41% ± 11%	Explore
plasmablast	11 studies	61% ± 25%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	46% ± 18%	Explore
dendritic cell	11 studies	50% ± 21%	Explore
endothelial cell of artery	11 studies	46% ± 16%	Explore
vein endothelial cell	11 studies	40% ± 16%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	48% ± 18%	Explore
secretory cell	10 studies	48% ± 19%	Explore
endothelial cell of vascular tree	10 studies	37% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	41% ± 18%	Explore
myeloid cell	9 studies	40% ± 15%	Explore
type II pneumocyte	7 studies	39% ± 20%	Explore
club cell	7 studies	37% ± 14%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	55% ± 19%	Explore
abnormal cell	7 studies	46% ± 19%	Explore
goblet cell	7 studies	29% ± 13%	Explore
mesothelial cell	7 studies	47% ± 15%	Explore
IgA plasma cell	7 studies	53% ± 17%	Explore
IgG plasma cell	7 studies	48% ± 16%	Explore
T follicular helper cell	7 studies	42% ± 12%	Explore
type I pneumocyte	6 studies	40% ± 15%	Explore
innate lymphoid cell	6 studies	32% ± 12%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	53% ± 21%	Explore
leukocyte	6 studies	30% ± 11%	Explore
epithelial cell of proximal tubule	6 studies	28% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	47% ± 14%	Explore
exhausted T cell	5 studies	57% ± 11%	Explore
respiratory goblet cell	5 studies	38% ± 14%	Explore
mononuclear phagocyte	5 studies	33% ± 12%	Explore
erythrocyte	5 studies	38% ± 17%	Explore
CD4-positive helper T cell	4 studies	34% ± 13%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	40% ± 21%	Explore
hematopoietic precursor cell	4 studies	41% ± 12%	Explore
ionocyte	4 studies	31% ± 16%	Explore
pancreatic A cell	4 studies	64% ± 18%	Explore
type B pancreatic cell	4 studies	59% ± 26%	Explore
glomerular endothelial cell	4 studies	47% ± 4%	Explore
kidney loop of Henle epithelial cell	4 studies	35% ± 16%	Explore
progenitor cell	4 studies	41% ± 14%	Explore
renal alpha-intercalated cell	4 studies	47% ± 17%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	39% ± 12%	Explore
transit amplifying cell	4 studies	23% ± 6%	Explore
hematopoietic stem cell	4 studies	60% ± 10%	Explore
precursor B cell	4 studies	36% ± 7%	Explore
pro-B cell	4 studies	36% ± 9%	Explore
enterocyte	4 studies	22% ± 5%	Explore
neuron	4 studies	45% ± 10%	Explore
adventitial cell	4 studies	34% ± 9%	Explore
alveolar macrophage	4 studies	29% ± 6%	Explore
intermediate monocyte	4 studies	53% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	63% ± 13%	Explore
T-helper 17 cell	4 studies	49% ± 22%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	58% ± 20%	Explore
deuterosomal cell	3 studies	38% ± 13%	Explore
duct epithelial cell	3 studies	43% ± 21%	Explore
platelet	3 studies	24% ± 6%	Explore
pancreatic D cell	3 studies	64% ± 24%	Explore
podocyte	3 studies	41% ± 3%	Explore
neural crest cell	3 studies	24% ± 5%	Explore
extravillous trophoblast	3 studies	57% ± 14%	Explore
common myeloid progenitor	3 studies	53% ± 28%	Explore
erythroblast	3 studies	39% ± 16%	Explore
lymphocyte	3 studies	45% ± 10%	Explore
immature B cell	3 studies	36% ± 7%	Explore
mucus secreting cell	3 studies	46% ± 4%	Explore
serous secreting cell	3 studies	47% ± 4%	Explore
germinal center B cell	3 studies	24% ± 6%	Explore
acinar cell	3 studies	51% ± 29%	Explore
pancreatic ductal cell	3 studies	60% ± 21%	Explore
granulocyte	3 studies	28% ± 13%	Explore
enteroendocrine cell	3 studies	44% ± 20%	Explore
intestinal crypt stem cell	3 studies	20% ± 4%	Explore
group 3 innate lymphoid cell	3 studies	33% ± 7%	Explore
T-helper 1 cell	3 studies	59% ± 14%	Explore
double negative thymocyte	3 studies	51% ± 5%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	37% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	43% ± 10%	Explore
lung	13 studies	38% ± 14%	Explore
intestine	9 studies	28% ± 13%	Explore
kidney	7 studies	35% ± 11%	Explore
pancreas	4 studies	59% ± 23%	Explore
uterus	4 studies	50% ± 9%	Explore
lymph node	4 studies	42% ± 8%	Explore
liver	4 studies	32% ± 15%	Explore
placenta	3 studies	40% ± 15%	Explore
bone marrow	3 studies	39% ± 14%	Explore
breast	3 studies	29% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	3864.03	180 / 180	96%	3.70	413 / 430
esophagus	100%	3395.34	1445 / 1445	95%	2.41	173 / 183
uterus	100%	4969.39	170 / 170	94%	3.32	431 / 459
bladder	100%	3836.43	21 / 21	94%	3.34	472 / 504
breast	100%	4216.52	459 / 459	92%	3.20	1034 / 1118
pancreas	100%	3432.26	328 / 328	91%	3.04	162 / 178
intestine	100%	4052.00	966 / 966	91%	2.97	479 / 527
lung	100%	3519.04	578 / 578	90%	3.65	1041 / 1155
brain	100%	2068.82	2635 / 2642	90%	2.66	631 / 705
stomach	100%	3708.04	359 / 359	85%	2.40	242 / 286
thymus	100%	4443.29	653 / 653	77%	1.69	466 / 605
skin	100%	3184.56	1809 / 1809	75%	1.95	355 / 472
prostate	100%	3685.26	245 / 245	72%	1.43	359 / 502
liver	100%	2669.23	226 / 226	63%	1.67	257 / 406
kidney	100%	3220.31	89 / 89	61%	1.84	551 / 901
adrenal gland	100%	3866.08	258 / 258	60%	1.05	139 / 230
adipose	100%	3972.75	1204 / 1204	0%	0	0 / 0
spleen	100%	4342.66	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	3.07	1 / 1
blood vessel	100%	3802.64	1334 / 1335	0%	0	0 / 0
heart	100%	2549.98	859 / 861	0%	0	0 / 0
muscle	99%	2042.26	793 / 803	0%	0	0 / 0
peripheral blood	98%	2151.44	908 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	90%	3.14	26 / 29
tonsil	0%	0	0 / 0	78%	1.65	35 / 45
eye	0%	0	0 / 0	39%	0.76	31 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	KRTCAP2
Protein name	Keratinocyte-associated protein 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2) Keratinocyte-associated protein 2 (KCP-2) (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2) (Oligosaccharyl transferase subunit KCP2)
Synonyms	hCG_1996357 KCP2
Description	FUNCTION: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity . May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1 . .
Accessions	ENST00000491084.5 A0A6I8PLE4 A0A6I8PRU6 A0A6I8PLD9 ENST00000295682.6 [Q8N6L1-1] ENST00000497317.5 Q8N6L1 ENST00000482246.5

GO_0042543	Biological process	protein N-linked glycosylation via arginine
GO_0006487	Biological process	protein N-linked glycosylation
GO_0008250	Cellular component	oligosaccharyltransferase complex
GO_0008047	Molecular function	enzyme activator activity

KRTCAP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review