IGBP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043154Biological processnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO_0007165Biological processsignal transduction
GO_0032873Biological processnegative regulation of stress-activated MAPK cascade
GO_0035303Biological processregulation of dephosphorylation
GO_0070555Biological processresponse to interleukin-1
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0042113Biological processB cell activation
GO_0034612Biological processresponse to tumor necrosis factor
GO_0060632Biological processregulation of microtubule-based movement
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0051721Molecular functionprotein phosphatase 2A binding
GO_0019888Molecular functionprotein phosphatase regulator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameIGBP1
Protein nameImmunoglobulin-binding protein 1 (B-cell signal transduction molecule alpha 4) (Protein alpha-4) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (Renal carcinoma antigen NY-REN-16)
SynonymsIBP1
DescriptionFUNCTION: Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits. .

AccessionsENST00000356413.5
P78318
ENST00000342206.10