EIF4A1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0002183Biological processcytoplasmic translational initiation
GO_0006413Biological processtranslational initiation
GO_0016020Cellular componentmembrane
GO_0070062Cellular componentextracellular exosome
GO_0016281Cellular componenteukaryotic translation initiation factor 4F complex
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0000339Molecular functionRNA cap binding
GO_0008135Molecular functiontranslation factor activity, RNA binding
GO_0004386Molecular functionhelicase activity
GO_0003724Molecular functionRNA helicase activity
GO_0003743Molecular functiontranslation initiation factor activity
GO_0003729Molecular functionmRNA binding
GO_0005524Molecular functionATP binding
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity
GO_0003725Molecular functiondouble-stranded RNA binding

IV. Literature review

[source]
Gene nameEIF4A1
Protein nameEukaryotic initiation factor 4AI
Eukaryotic translation initiation factor 4A1
RNA helicase (EC 3.6.4.13)
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
Eukaryotic initiation factor 4A-I (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
SynonymsDDX2A
EIF4A
DescriptionFUNCTION: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. .

FUNCTION: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. .

FUNCTION: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. .

FUNCTION: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. .

FUNCTION: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. .

FUNCTION: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. .

FUNCTION: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. .

FUNCTION: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. .

FUNCTION: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. .

AccessionsJ3KT12
ENST00000583802.5
J3KS93
J3QQP0
J3QL43
ENST00000578476.5
J3QLN6
ENST00000584784.5
J3QL52
J3QRP5
J3QS69
J3QKZ9
ENST00000578495.5
ENST00000581384.5
J3KRC2
ENST00000580461.5
ENST00000581544.5
ENST00000585024.5
ENST00000583389.5
ENST00000579139.1
J3KS25
ENST00000582169.5
P60842
J3QR64
J3KSZ0
ENST00000578754.5
ENST00000582050.1
ENST00000582746.5
Q9NZR9
ENST00000577269.5 [P60842-2]
ENST00000293831.13 [P60842-1]
ENST00000577929.1
J3KTN0