YPEL5 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	37 studies	42% ± 15%	Explore
natural killer cell	31 studies	35% ± 13%	Explore
CD8-positive, alpha-beta T cell	29 studies	38% ± 15%	Explore
T cell	28 studies	37% ± 15%	Explore
macrophage	26 studies	24% ± 6%	Explore
conventional dendritic cell	26 studies	35% ± 17%	Explore
CD4-positive, alpha-beta T cell	26 studies	41% ± 16%	Explore
classical monocyte	23 studies	36% ± 17%	Explore
non-classical monocyte	21 studies	40% ± 19%	Explore
plasmacytoid dendritic cell	21 studies	58% ± 19%	Explore
fibroblast	21 studies	24% ± 8%	Explore
endothelial cell	20 studies	25% ± 10%	Explore
smooth muscle cell	19 studies	27% ± 7%	Explore
regulatory T cell	19 studies	40% ± 12%	Explore
memory B cell	18 studies	46% ± 18%	Explore
naive B cell	18 studies	42% ± 15%	Explore
dendritic cell	17 studies	46% ± 22%	Explore
mature NK T cell	17 studies	34% ± 10%	Explore
pericyte	17 studies	24% ± 6%	Explore
monocyte	16 studies	30% ± 10%	Explore
basal cell	16 studies	28% ± 13%	Explore
plasma cell	15 studies	38% ± 14%	Explore
epithelial cell	15 studies	35% ± 19%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	34% ± 17%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	35% ± 17%	Explore
ciliated cell	14 studies	36% ± 18%	Explore
gamma-delta T cell	14 studies	43% ± 18%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	36% ± 17%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	39% ± 15%	Explore
mucosal invariant T cell	11 studies	41% ± 18%	Explore
platelet	10 studies	34% ± 10%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	44% ± 27%	Explore
neutrophil	10 studies	30% ± 9%	Explore
myeloid cell	10 studies	32% ± 14%	Explore
connective tissue cell	9 studies	26% ± 6%	Explore
endothelial cell of vascular tree	9 studies	20% ± 2%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	52% ± 18%	Explore
type I pneumocyte	8 studies	27% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	47% ± 17%	Explore
myofibroblast cell	8 studies	26% ± 9%	Explore
mast cell	7 studies	26% ± 6%	Explore
leukocyte	7 studies	44% ± 15%	Explore
IgG plasma cell	7 studies	27% ± 13%	Explore
innate lymphoid cell	7 studies	38% ± 15%	Explore
secretory cell	7 studies	31% ± 14%	Explore
T follicular helper cell	7 studies	50% ± 16%	Explore
plasmablast	6 studies	42% ± 19%	Explore
kidney loop of Henle epithelial cell	6 studies	19% ± 4%	Explore
endothelial cell of artery	6 studies	18% ± 3%	Explore
IgA plasma cell	6 studies	27% ± 9%	Explore
retinal cone cell	6 studies	43% ± 27%	Explore
abnormal cell	6 studies	29% ± 12%	Explore
hematopoietic stem cell	6 studies	33% ± 11%	Explore
precursor B cell	6 studies	56% ± 15%	Explore
endothelial cell of lymphatic vessel	5 studies	20% ± 6%	Explore
type II pneumocyte	5 studies	25% ± 10%	Explore
CD4-positive helper T cell	5 studies	44% ± 19%	Explore
hematopoietic precursor cell	5 studies	34% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	42% ± 22%	Explore
mononuclear phagocyte	5 studies	35% ± 17%	Explore
neuron	5 studies	26% ± 11%	Explore
pro-B cell	5 studies	39% ± 7%	Explore
immature B cell	5 studies	56% ± 11%	Explore
goblet cell	5 studies	25% ± 7%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	31% ± 17%	Explore
pancreatic A cell	4 studies	37% ± 18%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	43% ± 15%	Explore
retinal rod cell	4 studies	32% ± 15%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	47% ± 20%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	25% ± 7%	Explore
GABAergic neuron	4 studies	33% ± 10%	Explore
vein endothelial cell	4 studies	20% ± 3%	Explore
group 3 innate lymphoid cell	4 studies	54% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	26% ± 5%	Explore
erythrocyte	4 studies	28% ± 9%	Explore
ionocyte	3 studies	22% ± 8%	Explore
squamous epithelial cell	3 studies	61% ± 14%	Explore
type B pancreatic cell	3 studies	40% ± 12%	Explore
monocyte-derived dendritic cell	3 studies	44% ± 30%	Explore
exhausted T cell	3 studies	42% ± 10%	Explore
progenitor cell	3 studies	20% ± 3%	Explore
retinal bipolar neuron	3 studies	35% ± 13%	Explore
retinal ganglion cell	3 studies	63% ± 23%	Explore
placental villous trophoblast	3 studies	24% ± 9%	Explore
megakaryocyte	3 studies	45% ± 8%	Explore
club cell	3 studies	31% ± 3%	Explore
amacrine cell	3 studies	31% ± 9%	Explore
astrocyte	3 studies	23% ± 10%	Explore
retina horizontal cell	3 studies	30% ± 8%	Explore
retinal pigment epithelial cell	3 studies	41% ± 15%	Explore
serous secreting cell	3 studies	21% ± 3%	Explore
lymphocyte	3 studies	36% ± 20%	Explore
Mueller cell	3 studies	30% ± 4%	Explore
respiratory goblet cell	3 studies	26% ± 14%	Explore
germinal center B cell	3 studies	32% ± 8%	Explore
intermediate monocyte	3 studies	60% ± 13%	Explore
glutamatergic neuron	3 studies	51% ± 10%	Explore
oligodendrocyte precursor cell	3 studies	27% ± 9%	Explore
granulocyte	3 studies	33% ± 10%	Explore
mesothelial cell	3 studies	36% ± 14%	Explore
alveolar macrophage	3 studies	20% ± 2%	Explore
T-helper 17 cell	3 studies	47% ± 20%	Explore
double negative thymocyte	3 studies	46% ± 15%	Explore
double-positive, alpha-beta thymocyte	3 studies	49% ± 23%	Explore
progenitor cell of mammary luminal epithelium	3 studies	31% ± 13%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	29% ± 11%	Explore
peripheral blood	14 studies	40% ± 17%	Explore
intestine	10 studies	29% ± 13%	Explore
kidney	8 studies	23% ± 8%	Explore
eye	7 studies	29% ± 12%	Explore
uterus	5 studies	30% ± 12%	Explore
brain	5 studies	32% ± 7%	Explore
pancreas	4 studies	35% ± 16%	Explore
bone marrow	4 studies	31% ± 14%	Explore
prostate	4 studies	21% ± 6%	Explore
lymph node	4 studies	39% ± 15%	Explore
breast	4 studies	30% ± 7%	Explore
placenta	3 studies	32% ± 12%	Explore
thymus	3 studies	32% ± 10%	Explore
liver	3 studies	35% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6386.45	1445 / 1445	100%	63.66	183 / 183
ovary	100%	5578.51	180 / 180	100%	70.51	430 / 430
prostate	100%	5923.03	245 / 245	100%	127.81	502 / 502
uterus	100%	5187.51	170 / 170	100%	93.35	459 / 459
lung	100%	6585.34	578 / 578	100%	108.77	1154 / 1155
kidney	100%	5867.90	89 / 89	100%	92.61	900 / 901
thymus	100%	5045.18	653 / 653	100%	122.84	604 / 605
breast	100%	5863.02	459 / 459	100%	103.67	1116 / 1118
brain	100%	5775.55	2637 / 2642	100%	108.47	705 / 705
bladder	100%	6031.81	21 / 21	100%	92.70	503 / 504
stomach	100%	4454.59	359 / 359	100%	53.44	285 / 286
adrenal gland	100%	5749.76	258 / 258	100%	130.01	229 / 230
intestine	100%	6350.09	966 / 966	98%	57.51	518 / 527
liver	99%	2448.95	223 / 226	100%	60.49	404 / 406
skin	100%	5232.74	1808 / 1809	97%	67.68	458 / 472
pancreas	97%	2076.02	318 / 328	100%	97.97	178 / 178
adipose	100%	6596.15	1204 / 1204	0%	0	0 / 0
blood vessel	100%	8392.21	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	95.01	29 / 29
spleen	100%	5920.93	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	84.77	45 / 45
ureter	0%	0	0 / 0	100%	57.44	1 / 1
muscle	100%	3644.62	799 / 803	0%	0	0 / 0
peripheral blood	99%	5776.11	922 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	98%	51.58	78 / 80
heart	96%	3018.96	824 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0008283	Biological process	cell population proliferation
GO_0005813	Cellular component	centrosome
GO_0000151	Cellular component	ubiquitin ligase complex
GO_0097431	Cellular component	mitotic spindle pole
GO_1904724	Cellular component	tertiary granule lumen
GO_1904813	Cellular component	ficolin-1-rich granule lumen
GO_0030496	Cellular component	midbody
GO_0005576	Cellular component	extracellular region
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

Gene name	YPEL5
Protein name	Protein yippee-like 5
Synonyms	CGI-127
Description	FUNCTION: Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 . Required for normal cell proliferation (By similarity). .
Accessions	ENST00000402003.7 ENST00000261353.9 P62699 ENST00000379520.7 ENST00000402708.5 ENST00000379519.7

YPEL5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review