VDAC3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	24 studies	24% ± 8%	Explore
endothelial cell	22 studies	27% ± 13%	Explore
fibroblast	22 studies	24% ± 10%	Explore
ciliated cell	17 studies	42% ± 15%	Explore
smooth muscle cell	17 studies	25% ± 7%	Explore
T cell	16 studies	24% ± 7%	Explore
CD8-positive, alpha-beta T cell	16 studies	30% ± 13%	Explore
pericyte	16 studies	23% ± 7%	Explore
endothelial cell of lymphatic vessel	15 studies	26% ± 10%	Explore
CD4-positive, alpha-beta T cell	15 studies	30% ± 17%	Explore
epithelial cell	12 studies	35% ± 17%	Explore
regulatory T cell	12 studies	28% ± 13%	Explore
conventional dendritic cell	11 studies	29% ± 16%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	22% ± 7%	Explore
plasmacytoid dendritic cell	11 studies	28% ± 9%	Explore
gamma-delta T cell	11 studies	24% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	24% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	10 studies	19% ± 4%	Explore
glutamatergic neuron	10 studies	35% ± 23%	Explore
platelet	9 studies	35% ± 12%	Explore
basal cell	9 studies	33% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	22% ± 4%	Explore
myofibroblast cell	9 studies	24% ± 5%	Explore
macrophage	9 studies	24% ± 9%	Explore
astrocyte	9 studies	27% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	25% ± 11%	Explore
non-classical monocyte	8 studies	25% ± 10%	Explore
mature NK T cell	8 studies	20% ± 3%	Explore
connective tissue cell	8 studies	30% ± 8%	Explore
neuron	8 studies	42% ± 16%	Explore
mucosal invariant T cell	7 studies	20% ± 3%	Explore
GABAergic neuron	7 studies	42% ± 16%	Explore
oligodendrocyte precursor cell	7 studies	27% ± 8%	Explore
plasma cell	6 studies	30% ± 12%	Explore
plasmablast	6 studies	45% ± 21%	Explore
epithelial cell of proximal tubule	6 studies	20% ± 4%	Explore
progenitor cell	6 studies	20% ± 3%	Explore
abnormal cell	6 studies	28% ± 11%	Explore
retinal ganglion cell	6 studies	66% ± 30%	Explore
dendritic cell	6 studies	33% ± 20%	Explore
amacrine cell	6 studies	42% ± 17%	Explore
retinal rod cell	6 studies	24% ± 5%	Explore
hematopoietic precursor cell	5 studies	35% ± 18%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	39% ± 14%	Explore
classical monocyte	5 studies	28% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	23% ± 2%	Explore
erythroblast	5 studies	44% ± 18%	Explore
hematopoietic stem cell	5 studies	32% ± 9%	Explore
B cell	5 studies	22% ± 10%	Explore
retina horizontal cell	5 studies	46% ± 11%	Explore
retinal cone cell	5 studies	27% ± 10%	Explore
monocyte	5 studies	21% ± 4%	Explore
cardiac muscle cell	5 studies	33% ± 4%	Explore
endothelial cell of vascular tree	5 studies	18% ± 2%	Explore
transit amplifying cell	5 studies	25% ± 7%	Explore
interneuron	5 studies	39% ± 15%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	33% ± 11%	Explore
deuterosomal cell	4 studies	34% ± 5%	Explore
leukocyte	4 studies	23% ± 10%	Explore
exhausted T cell	4 studies	29% ± 11%	Explore
kidney loop of Henle epithelial cell	4 studies	28% ± 6%	Explore
endothelial cell of artery	4 studies	18% ± 2%	Explore
mesothelial cell	4 studies	32% ± 19%	Explore
lymphocyte	4 studies	25% ± 8%	Explore
megakaryocyte	4 studies	48% ± 18%	Explore
erythrocyte	4 studies	44% ± 20%	Explore
muscle cell	4 studies	31% ± 12%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	39% ± 9%	Explore
innate lymphoid cell	4 studies	18% ± 2%	Explore
type I pneumocyte	4 studies	24% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	33% ± 15%	Explore
enteroendocrine cell	4 studies	28% ± 15%	Explore
goblet cell	4 studies	25% ± 11%	Explore
oligodendrocyte	4 studies	21% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	21% ± 5%	Explore
memory B cell	4 studies	19% ± 4%	Explore
pancreatic A cell	3 studies	48% ± 17%	Explore
type B pancreatic cell	3 studies	51% ± 13%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	29% ± 5%	Explore
enterocyte	3 studies	18% ± 2%	Explore
neural crest cell	3 studies	35% ± 3%	Explore
vein endothelial cell	3 studies	19% ± 3%	Explore
retinal bipolar neuron	3 studies	35% ± 12%	Explore
glycinergic amacrine cell	3 studies	30% ± 13%	Explore
common myeloid progenitor	3 studies	32% ± 21%	Explore
myeloid cell	3 studies	28% ± 10%	Explore
brush cell	3 studies	27% ± 11%	Explore
club cell	3 studies	23% ± 3%	Explore
capillary endothelial cell	3 studies	23% ± 5%	Explore
pro-B cell	3 studies	19% ± 1%	Explore
Mueller cell	3 studies	20% ± 3%	Explore
OFF-bipolar cell	3 studies	48% ± 33%	Explore
ON-bipolar cell	3 studies	49% ± 33%	Explore
rod bipolar cell	3 studies	31% ± 5%	Explore
adipocyte	3 studies	23% ± 3%	Explore
pancreatic ductal cell	3 studies	43% ± 20%	Explore
granulocyte monocyte progenitor cell	3 studies	33% ± 21%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	52% ± 20%	Explore
intestinal crypt stem cell	3 studies	27% ± 8%	Explore
T follicular helper cell	3 studies	18% ± 3%	Explore
secretory cell	3 studies	34% ± 19%	Explore
T-helper 1 cell	3 studies	34% ± 18%	Explore
double negative thymocyte	3 studies	36% ± 18%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	12 studies	23% ± 6%	Explore
lung	10 studies	29% ± 13%	Explore
brain	10 studies	31% ± 16%	Explore
eye	9 studies	26% ± 8%	Explore
intestine	7 studies	23% ± 11%	Explore
kidney	6 studies	20% ± 2%	Explore
heart	5 studies	19% ± 2%	Explore
liver	5 studies	33% ± 22%	Explore
bone marrow	4 studies	21% ± 4%	Explore
pancreas	3 studies	48% ± 13%	Explore
lymph node	3 studies	24% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	3398.08	459 / 459	100%	131.66	1118 / 1118
esophagus	100%	5370.19	1445 / 1445	100%	92.34	183 / 183
intestine	100%	5696.35	966 / 966	100%	114.95	527 / 527
ovary	100%	2998.69	180 / 180	100%	98.40	430 / 430
stomach	100%	3524.69	359 / 359	100%	102.63	286 / 286
uterus	100%	3788.63	170 / 170	100%	120.81	458 / 459
thymus	100%	4444.58	653 / 653	100%	82.81	603 / 605
bladder	100%	4236.38	21 / 21	100%	111.33	502 / 504
kidney	100%	3942.06	89 / 89	100%	84.82	897 / 901
skin	100%	3621.04	1804 / 1809	100%	91.09	471 / 472
brain	99%	5974.07	2627 / 2642	100%	108.02	705 / 705
prostate	100%	3378.18	244 / 245	100%	72.26	501 / 502
lung	99%	3348.89	574 / 578	100%	115.11	1154 / 1155
adrenal gland	100%	4489.92	258 / 258	99%	86.45	228 / 230
pancreas	98%	2181.47	323 / 328	100%	71.52	178 / 178
liver	100%	2593.06	226 / 226	98%	62.47	398 / 406
lymph node	0%	0	0 / 0	100%	90.01	29 / 29
muscle	100%	15565.22	803 / 803	0%	0	0 / 0
spleen	100%	4130.63	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	103.22	45 / 45
ureter	0%	0	0 / 0	100%	61.01	1 / 1
adipose	100%	3606.47	1203 / 1204	0%	0	0 / 0
blood vessel	100%	4262.33	1331 / 1335	0%	0	0 / 0
heart	98%	9243.12	840 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	96%	57.56	77 / 80
peripheral blood	82%	3358.57	765 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0001662	Biological process	behavioral fear response
GO_0007283	Biological process	spermatogenesis
GO_0007270	Biological process	neuron-neuron synaptic transmission
GO_0015853	Biological process	adenine transport
GO_0007612	Biological process	learning
GO_0098656	Biological process	monoatomic anion transmembrane transport
GO_0120317	Biological process	sperm mitochondrial sheath assembly
GO_0005741	Cellular component	mitochondrial outer membrane
GO_0070062	Cellular component	extracellular exosome
GO_0045202	Cellular component	synapse
GO_0016020	Cellular component	membrane
GO_0046930	Cellular component	pore complex
GO_0005739	Cellular component	mitochondrion
GO_0005634	Cellular component	nucleus
GO_0015288	Molecular function	porin activity
GO_0005515	Molecular function	protein binding
GO_0008308	Molecular function	voltage-gated monoatomic anion channel activity
GO_0000166	Molecular function	nucleotide binding

IV. Literature review

[source]

Gene name	VDAC3
Protein name	Voltage-dependent anion-selective channel protein 3 Voltage-dependent anion channel Voltage dependent anion channel 3 Voltage-dependent anion-selective channel protein 3 (VDAC-3) (hVDAC3) (Outer mitochondrial membrane protein porin 3)
Synonyms
Description	FUNCTION: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity). Involved in male fertility and sperm mitochondrial sheath formation (By similarity). .
Accessions	ENST00000522010.1 ENST00000518495.5 ENST00000022615.9 [Q9Y277-1] E5RJN6 ENST00000522069.5 ENST00000518563.5 ENST00000521158.5 [Q9Y277-2] ENST00000522572.5 E5RHE1 Q9Y277 ENST00000520115.5 E5RK27 E5RFP6 Q36731 E5RHZ6 E5RFL1

VDAC3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review