TMEM14C | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	33 studies	38% ± 14%	Explore
macrophage	29 studies	37% ± 11%	Explore
endothelial cell	27 studies	36% ± 14%	Explore
conventional dendritic cell	26 studies	43% ± 12%	Explore
pericyte	24 studies	39% ± 12%	Explore
smooth muscle cell	23 studies	37% ± 13%	Explore
epithelial cell	18 studies	41% ± 20%	Explore
dendritic cell	17 studies	48% ± 21%	Explore
basal cell	17 studies	40% ± 18%	Explore
endothelial cell of lymphatic vessel	16 studies	44% ± 12%	Explore
connective tissue cell	16 studies	41% ± 13%	Explore
mast cell	15 studies	28% ± 13%	Explore
ciliated cell	15 studies	41% ± 17%	Explore
non-classical monocyte	15 studies	28% ± 10%	Explore
plasmacytoid dendritic cell	15 studies	33% ± 10%	Explore
classical monocyte	14 studies	26% ± 10%	Explore
CD4-positive, alpha-beta T cell	13 studies	24% ± 6%	Explore
myofibroblast cell	13 studies	43% ± 13%	Explore
monocyte	13 studies	28% ± 10%	Explore
capillary endothelial cell	12 studies	27% ± 9%	Explore
vein endothelial cell	11 studies	32% ± 11%	Explore
B cell	11 studies	20% ± 8%	Explore
regulatory T cell	11 studies	22% ± 5%	Explore
plasma cell	10 studies	28% ± 10%	Explore
secretory cell	10 studies	38% ± 18%	Explore
endothelial cell of artery	10 studies	24% ± 5%	Explore
mesothelial cell	10 studies	53% ± 20%	Explore
progenitor cell	9 studies	42% ± 12%	Explore
abnormal cell	9 studies	39% ± 15%	Explore
endothelial cell of vascular tree	9 studies	31% ± 7%	Explore
myeloid cell	9 studies	38% ± 17%	Explore
type I pneumocyte	8 studies	38% ± 11%	Explore
club cell	7 studies	36% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	22% ± 5%	Explore
epithelial cell of proximal tubule	7 studies	34% ± 12%	Explore
goblet cell	7 studies	29% ± 14%	Explore
CD8-positive, alpha-beta T cell	7 studies	21% ± 6%	Explore
type II pneumocyte	6 studies	40% ± 16%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	21% ± 4%	Explore
T cell	6 studies	26% ± 14%	Explore
ionocyte	6 studies	34% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	19% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	18% ± 2%	Explore
kidney loop of Henle epithelial cell	6 studies	37% ± 11%	Explore
renal alpha-intercalated cell	6 studies	42% ± 5%	Explore
enterocyte	6 studies	30% ± 7%	Explore
erythroblast	6 studies	55% ± 22%	Explore
leukocyte	6 studies	32% ± 13%	Explore
gamma-delta T cell	6 studies	28% ± 15%	Explore
erythrocyte	6 studies	53% ± 25%	Explore
memory B cell	6 studies	18% ± 2%	Explore
alveolar macrophage	5 studies	37% ± 8%	Explore
respiratory goblet cell	5 studies	24% ± 9%	Explore
mononuclear phagocyte	5 studies	43% ± 22%	Explore
enteroendocrine cell	5 studies	35% ± 15%	Explore
intestinal crypt stem cell	5 studies	33% ± 7%	Explore
transit amplifying cell	5 studies	27% ± 11%	Explore
mucosal invariant T cell	5 studies	20% ± 2%	Explore
neuron	5 studies	43% ± 17%	Explore
astrocyte	5 studies	29% ± 19%	Explore
plasmablast	4 studies	41% ± 18%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	50% ± 5%	Explore
retinal ganglion cell	4 studies	49% ± 28%	Explore
hematopoietic stem cell	4 studies	44% ± 9%	Explore
microglial cell	4 studies	30% ± 12%	Explore
adventitial cell	4 studies	30% ± 7%	Explore
T follicular helper cell	4 studies	20% ± 3%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	37% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	20% ± 5%	Explore
hematopoietic precursor cell	3 studies	52% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	19% ± 3%	Explore
deuterosomal cell	3 studies	25% ± 10%	Explore
duct epithelial cell	3 studies	35% ± 11%	Explore
precursor cell	3 studies	50% ± 9%	Explore
squamous epithelial cell	3 studies	34% ± 25%	Explore
pancreatic A cell	3 studies	40% ± 3%	Explore
type B pancreatic cell	3 studies	51% ± 8%	Explore
glomerular endothelial cell	3 studies	25% ± 5%	Explore
neural crest cell	3 studies	48% ± 8%	Explore
extravillous trophoblast	3 studies	39% ± 10%	Explore
placental villous trophoblast	3 studies	46% ± 14%	Explore
lymphocyte	3 studies	30% ± 7%	Explore
brush cell	3 studies	33% ± 13%	Explore
neuroendocrine cell	3 studies	37% ± 14%	Explore
retinal cone cell	3 studies	52% ± 15%	Explore
retinal rod cell	3 studies	31% ± 12%	Explore
serous secreting cell	3 studies	35% ± 2%	Explore
Mueller cell	3 studies	41% ± 12%	Explore
muscle cell	3 studies	32% ± 19%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	24% ± 4%	Explore
intermediate monocyte	3 studies	34% ± 6%	Explore
myoepithelial cell	3 studies	40% ± 18%	Explore
luminal cell of prostate epithelium	3 studies	33% ± 8%	Explore
pancreatic ductal cell	3 studies	50% ± 10%	Explore
oligodendrocyte precursor cell	3 studies	32% ± 11%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	58% ± 23%	Explore
innate lymphoid cell	3 studies	19% ± 1%	Explore
glial cell	3 studies	41% ± 22%	Explore
hepatocyte	3 studies	40% ± 31%	Explore
group 3 innate lymphoid cell	3 studies	33% ± 14%	Explore
keratinocyte	3 studies	19% ± 3%	Explore
T-helper 17 cell	3 studies	19% ± 4%	Explore
natural killer cell	3 studies	20% ± 3%	Explore
naive B cell	3 studies	18% ± 4%	Explore
progenitor cell of mammary luminal epithelium	3 studies	32% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	34% ± 16%	Explore
intestine	11 studies	31% ± 13%	Explore
kidney	9 studies	29% ± 9%	Explore
peripheral blood	8 studies	22% ± 5%	Explore
eye	6 studies	29% ± 13%	Explore
uterus	5 studies	41% ± 14%	Explore
breast	4 studies	29% ± 5%	Explore
pancreas	3 studies	46% ± 4%	Explore
placenta	3 studies	37% ± 16%	Explore
ovary	3 studies	21% ± 5%	Explore
bone marrow	3 studies	24% ± 7%	Explore
liver	3 studies	50% ± 27%	Explore
lymph node	3 studies	31% ± 13%	Explore
brain	3 studies	29% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3847.50	1445 / 1445	100%	154.46	183 / 183
liver	100%	2226.72	226 / 226	100%	210.64	406 / 406
lung	100%	3660.43	578 / 578	100%	232.67	1155 / 1155
ovary	100%	4264.62	180 / 180	100%	338.17	430 / 430
pancreas	100%	2099.87	328 / 328	100%	206.36	178 / 178
prostate	100%	5198.59	245 / 245	100%	261.20	502 / 502
stomach	100%	3491.28	359 / 359	100%	196.86	286 / 286
skin	100%	4203.50	1808 / 1809	100%	297.80	472 / 472
kidney	100%	4622.82	89 / 89	100%	236.47	900 / 901
brain	100%	2793.01	2638 / 2642	100%	231.04	705 / 705
thymus	100%	4561.90	653 / 653	100%	283.22	604 / 605
intestine	100%	4291.62	966 / 966	100%	222.73	526 / 527
uterus	100%	4511.69	170 / 170	100%	253.38	458 / 459
adrenal gland	100%	6310.58	258 / 258	100%	222.60	229 / 230
breast	100%	4777.83	459 / 459	100%	263.09	1113 / 1118
bladder	100%	4035.52	21 / 21	99%	229.77	501 / 504
adipose	100%	4920.37	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5018.29	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	257.21	80 / 80
lymph node	0%	0	0 / 0	100%	152.30	29 / 29
muscle	100%	3545.17	803 / 803	0%	0	0 / 0
spleen	100%	2801.42	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	177.20	45 / 45
ureter	0%	0	0 / 0	100%	123.95	1 / 1
heart	99%	3804.14	854 / 861	0%	0	0 / 0
peripheral blood	49%	1108.68	458 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0030218	Biological process	erythrocyte differentiation
GO_0070453	Biological process	regulation of heme biosynthetic process
GO_0006839	Biological process	mitochondrial transport
GO_0006783	Biological process	heme biosynthetic process
GO_0071705	Biological process	nitrogen compound transport
GO_0031966	Cellular component	mitochondrial membrane
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005515	Molecular function	protein binding

Gene name	TMEM14C
Protein name	Transmembrane protein 14C
Synonyms	C6orf53 HSPC194
Description	FUNCTION: Required for normal heme biosynthesis. .
Accessions	ENST00000229563.6 ENST00000541412.5 Q9P0S9 ENST00000642513.1 ENST00000643226.2

TMEM14C report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review