SND1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006402Biological processmRNA catabolic process
GO_0001649Biological processosteoblast differentiation
GO_0010587Biological processmiRNA catabolic process
GO_0010564Biological processregulation of cell cycle process
GO_0031047Biological processregulatory ncRNA-mediated gene silencing
GO_0016020Cellular componentmembrane
GO_0070062Cellular componentextracellular exosome
GO_0097433Cellular componentdense body
GO_0031332Cellular componentRNAi effector complex
GO_0005829Cellular componentcytosol
GO_0042470Cellular componentmelanosome
GO_0005634Cellular componentnucleus
GO_0004521Molecular functionRNA endonuclease activity
GO_0004519Molecular functionendonuclease activity
GO_0016894Molecular functionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
GO_0045296Molecular functioncadherin binding
GO_0003712Molecular functiontranscription coregulator activity
GO_1905172Molecular functionRISC complex binding
GO_0004518Molecular functionnuclease activity
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSND1
Protein nameStaphylococcal nuclease domain-containing protein (EC 3.1.31.1)
Staphylococcal nuclease domain-containing protein 1 (EC 3.1.31.1) (100 kDa coactivator) (EBNA2 coactivator p100) (Tudor domain-containing protein 11) (p100 co-activator)
Staphylococcal nuclease and tudor domain containing 1
SynonymshCG_32326
TDRD11
DescriptionFUNCTION: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs . As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition . Functions as a bridging factor between STAT6 and the basal transcription factor . Plays a role in PIM1 regulation of MYB activity . Functions as a transcriptional coactivator for STAT5 (By similarity). .; FUNCTION: (Microbial infection) Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2). .; FUNCTION: (Microbial infection) Promotes SARS-CoV-2 RNA synthesis by binding to negative-sense RNA and the viral protein nsp9. .

FUNCTION: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. .

AccessionsENST00000486037.1
Q7KZF4
A0A140VK49
H7C597
ENST00000354725.8