RBM17 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045292Biological processmRNA cis splicing, via spliceosome
GO_0000380Biological processalternative mRNA splicing, via spliceosome
GO_0005654Cellular componentnucleoplasm
GO_0005681Cellular componentspliceosomal complex
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRBM17
Protein nameRNA binding motif protein 17
Alternative protein RBM17
Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)
Splicing factor 45 (RNA-binding motif protein 17)
SynonymsSPF45
hCG_24832
DescriptionFUNCTION: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. .

FUNCTION: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. .

AccessionsENST00000447032.1
H0Y6J6
Q5W009
Q5W010
Q96I25
ENST00000379888.9
Q5W011
ENST00000437845.6
ENST00000432931.5
Q5W012
ENST00000446108.5
L8EAL0
ENST00000418631.5